Search Results - "ZELLNER, James L"

A matrix metalloproteinase induction/activation system exists in the human left ventricular myocardium and is upregulated in heart failure by SPINALE, Francis G, COKER, Mytsi L, HEUNG, Lena J, BOND, Brian R, GUNASINGHE, Himali R, ETOH, Takuma, GOLDBERG, Aron T, ZELLNER, James L, CRUMBLEY, A. Jackson

“…Matrix metalloproteinases (MMPs) contribute to matrix remodeling in disease states such as tumor metastases. Extracellular matrix metalloproteinase inducer…”
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Selective endothelin-1 receptor type A inhibition in subjects undergoing cardiac surgery with preexisting left ventricular dysfunction: Influence on early postoperative hemodynamics by Toole, John M., MD, Ikonomidis, John S., MD, PhD, Szeto, Wilson Y., MD, Zellner, James L., MD, Mulcahy, John, BA, Deardorff, Rachael L., BS, Spinale, Francis G., MD, PhD

“…Objective A robust release of endothelin-1 with subsequent endothelin-A subtype receptor activation occurs in patients after cardiac surgery requiring…”
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Early and long-term results of coronary artery bypass grafting in dialysis patients by Franga, Dion L, Kratz, John M, Crumbley, A.Jackson, Zellner, James L, Stroud, Martha R, Crawford, Fred A

“…Background. Dialysis patients frequently present with debilitating coronary artery disease but are regarded as challenging patients for coronary artery bypass…”
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Endothelin-1 during and after cardiopulmonary bypass: Association to graft sensitivity and postoperative recovery by Bond, Brian R., Dorman, B.Hugh, Clair, Mark J., Walker, C.Allyson, Pinosky, Mark L., Reeves, Scott T., Walton, Scott, Kratz, John M., Zellner, James L., Crumbley, A.Jackson, Multani, Marlina M., Spinale, Francis G.

“…Objective: Our objectives are 2-fold: (1) to serially measure the release of endothelin and graft-conduit endothelin sensitivity during and after coronary…”
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Increased matrix metalloproteinase activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy by THOMAS, C. V, COKER, M. L, ZELLNER, J. L, HANDY, J. R, CRUMBLEY, A. J, SPINALE, F. G

“…One of the hallmarks of dilated cardiomyopathy (DCM) is left ventricular (LV) remodeling. The matrix metalloproteinases (MMPs) are a family of enzymes that…”
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Temporal synthesis and release of endothelin within the systemic and myocardial circulation during and after cardiopulmonary bypass: Relation to postoperative recovery by Dorman, B.Hugh, Bond, Brian R., Clair, Mark J., Walker, Courtney A., Pinosky, Mark L., Reeves, Scott T., Kratz, John M., Zellner, James L., Crumbley, Andrew J., Multani, Marlina M., Spinale, Francis G.

“…Objective: To determine endothelin levels in arterial, pulmonary, and myocardial vascular compartments in patients undergoing coronary artery bypass graft…”
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Differential Effects of Epsilon-aminocaproic Acid and Aprotinin on Matrix Metalloproteinase Release in Patients Following Cardiopulmonary Bypass by Dorman, Bruce H, Stroud, Robert E, Wyckoff, Michael M, Zellner, James L, Botta, Don, Leonardi, Amy H, Ikonomidis, John S, Spinale, Francis G

“…This study examined whether differential effects of 2 agents commonly used for hemostatic purposes during cardiac surgery, aprotinin and epsilon-aminocaproic…”
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Papaverine Delivery to the Internal Mammary Artery Pedicle Effectively Treats Spasm by Girard, Dhru S., Sutton, John P., Williams, Timothy H., Crumbley, Arthur J., Zellner, James L., Kratz, John M., Crawford, Fred A.

“…Left internal mammary artery spasm is well recognized during coronary artery bypass operations. Papaverine has been used by many surgeons to maximize mammary…”
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Long-term experience with the St. Jude medical valve prosthesis by Zellner, James L, Kratz, John M, Crumbley, Arthur J, Stroud, Martha R, Bradley, Scott M, Sade, Robert M, Crawford, Fred A

“…Background. All patients undergoing St. Jude Medical valve replacement at the Medical University of South Carolina since January 1979 have been followed…”
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Differential effects of calcium channel antagonists in the amelioration of radial artery vasospasm by Bond, B R, Zellner, J L, Dorman, B H, Multani, M M, Kratz, J M, Crumbley, 3rd, A J, Crawford, Jr, F A, Spinale, F G

“…Radial artery (RA) is being used for coronary artery bypass grafting (CABG) with greater frequency. However, RA is prone to post-CABG vasospasm, which may be…”
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Endothelin receptor pathway in human left ventricular myocytes: relation to contractility by Goldberg, Aron T, Bond, Brian R, Mukherjee, Rupak, New, R.Brent, Zellner, James L, Crawford, Fred A, Spinale, Francis G

“…Background. Increased synthesis and release of the potent bioactive peptide endothelin-1 (ET-1) occurs during and after cardiac surgery. However, the cellular…”
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Effects of adrenomedullin on human myocyte contractile function and beta-adrenergic response by Mukherjee, Rupak, Multani, M Marlina, Sample, Jeffrey A, Dowdy, Kathryn B, Zellner, James L, Hoover, Donald B, Spinale, Francis G

“…Adrenomedullin has been demonstrated to cause systemic vasodilation, and increased plasma adrenomedullin levels have been observed in cardiovascular disease…”
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Pneumoperitoneum to Treat Air Leaks and Spaces After a Lung Volume Reduction Operation by Handy, John R, Judson, Marc A, Zellner, James L

“…Lung volume reduction surgery is an option for the management of end-stage emphysema. The most frequent surgical complication of lung volume reduction is…”
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ATP-sensitive potassium channel activation before cardioplegia. Effects on ventricular and myocyte function by Dorman, B H, Hebbar, L, Zellner, J L, New, R B, Houck, W V, Acsell, J, Nettles, C, Hendrick, J W, Sampson, A P, Mukherjee, R, Spinale, F G

“…Pretreatment with potassium channel openers (PCOs) has been shown to provide protective effects in the setting of myocardial ischemia. The goal of the present…”
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Isolated left ventricular myocyte contractility in patients undergoing cardiac operations by New, R.Brent, Zellner, James L., Hebbar, Latha, Mukherjee, Rupak, Sampson, Angela C., Hendrick, Jennifer W., Handy, John R., Crawford, Fred, Spinale, Francis G.

“…Background: Because of methods required for obtaining isolated left ventricular myocytes, evaluation of the contractile function of isolated left ventricular…”
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Cardiopulmonary bypass in a gravid patient: perioperative changes in endothelin levels by Zellner, James L, Kribbs, Scott B, Dorman, B.Hugh, Spinale, Francis G

“…Transient elevations of the potent vasoconstrictive peptide endothelin have been reported to occur with the institution of cardiopulmonary bypass. We measured…”
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Coronary artery bypass grafting with and without cardiopulmonary bypass: a comparison analysis by Kirk, K C, Aldridge, R A, Sistino, J J, Zellner, J L, Crumbley, A J, Kratz, J M, Crawford, Jr, F A, Reeves, S T

“…Coronary artery bypass grafting (CABG) using stabilization devices in place of the heart-lung machine is being performed on a wide range of patients. This…”
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Chronic amlodipine treatment during the development of heart failure by SPINALE, F. G, MUKHERJEE, R, KROMBACH, R. S, CLAIR, M. J, HENDRICK, J. W, HOUCK, W. V, HEBBAR, L, KRIBBS, S. B, ZELLNER, J. L, DODD, M. G

“…This study examined the effects of chronic amlodipine treatment on left ventricular (LV) pump function, systemic hemodynamics, neurohormonal status, and…”
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Beneficial effects of myocyte preconditioning on contractile processes after cardioplegic arrest by Zellner, James L., Hebbar, Latha, Crawford, Fred A., Mukherjee, Rupak, Spinale, Francis G.

“…Myocardial preconditioning, which can be achieved through short intervals of ischemia or hypoxia followed by reperfusion, protects the myocardium with…”
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Temporal Relation of ATP-Sensitive Potassium-Channel Activation and Contractility Before Cardioplegia by Hebbar, Latha, Houck, Ward V., Zellner, James L., Dorman, B.Hugh, Spinale, Francis G.

“…Background. Pharmacologic treatment using potassium-channel openers (PCOs) before cardioplegic arrest has been demonstrated to provide beneficial effects on…”
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