Search Results - "ZELEZNA, B"

Potential neuroprotective and anti-apoptotic properties of a long-lasting stable analog of ghrelin: an in vitro study using SH-SY5Y cells by Popelová, A, Kákonová, A, Hrubá, L, Kuneš, J, Maletínská, L, Železná, B

“…Neurodegenerative disorders, such as Alzheimer's disease (AD) and Parkinson's disease (PD), are increasing in prevalence. Currently, there are no effective and…”
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Pharmacological characterization of lipidized analogs of prolactin-releasing peptide with a modified C- terminal aromatic ring by Prazienkova, V, Ticha, A, Blechova, M, Spolcova, A, Zelezna, B, Maletinska, L

“…Prolactin-releasing peptide (PrRP) is an anorexigenic neuropeptide expressed in the brain where it regulates food intake and energy expenditure. The C-terminal…”
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Estradiol supplementation helps overcome central leptin resistance of ovariectomized mice on a high fat diet by Matysková, R, Zelezná, B, Maixnerová, J, Koutová, D, Haluzík, M, Maletínská, L

“…Ovariectomized mice on a high fat diet represent a model of diet-induced obesity during estrogen deficiency. Here, we tested the hypothesis that sensitivity to…”
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Effect of ghrelin receptor agonist and antagonist on the activity of arcuate nucleus tyrosine hydroxylase containing neurons in C57BL/6 male mice exposed to normal or high fat diet by Pirnik, Z, Majercikova, Z, Holubova, M, Pirnik, R, Zelezna, B, Maletinska, L, Kiss, A

“…Catecholamines participate in the food intake regulation, however, there are no literature data available, dealing with the activity of tyrosine hydroxylase…”
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Pathophysiology of NAFLD and NASH in Experimental Models: The Role of Food Intake Regulating Peptides by Kořínková, L, Pražienková, V, Černá, L, Karnošová, A, Železná, B, Kuneš, J, Maletínská, Lenka

“…Obesity, diabetes, insulin resistance, sedentary lifestyle, and Western diet are the key factors underlying non-alcoholic fatty liver disease (NAFLD), one of…”
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Novel lipidized analogs of prolactin-releasing peptide have prolonged half-lives and exert anti-obesity effects after peripheral administration by Blechova, M, Kunes, J, Mikulaskova, B, Pirnik, Z, Maletinska, L, Lacinova, Z, Spolcova, A, Holubova, M, Zemenova, J, Haluzik, M, Zelezna, B, Nagelova, V, Ticha, A, Sykora, D

“…Objectives: Obesity is a frequent metabolic disorder but an effective therapy is still scarce. Anorexigenic neuropeptides produced and acting in the brain have…”
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Anorexigenic effect of cholecystokinin is lost but that of CART (Cocaine and Amphetamine Regulated Transcript) peptide is preserved in monosodium glutamate obese mice by Železná, B, Maixnerová, J, Matyšková, R, Haugvicová, R, Blokešová, D, Maletínská, L

“…Monosodium glutamate (MSG) treatment of neonatal mice results in a selective damage to the arcuate nucleus (ARC) and development of obesity with increased…”
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Angiotensin II Receptor Subtypes are Coupled with Distinct Signal- Transduction Mechanisms in Neurons and Astrocytes from Rat Brain by Sumners, C, Tang, W, Zelezna, B, Raizada, M K

“…Both neurons and astrocytes contain specific receptors for angiotensin II (AII). We used selective ligands for the AT1and AT2types of AII receptors to…”
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The Peptidic GHS-R antagonist [D-Lys3]GHRP-6 markedly improves adiposity and related metabolic abnormalities in a mouse model of postmenopausal obesity by Maletínská, L., Matyšková, R., Maixnerová, J., Sýkora, D., Pýchová, M., Špolcová, A., Blechová, M., Drápalová, J., Lacinová, Z., Haluzík, M., Železná, B.

“…► Estrogen deficient mice on high fat diet developed metabolic syndrome features. ► Ghrelin antagonist [D-Lys3]GHRP-6 improved metabolic parameters in these…”
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Inhibition of bacterial and boar epididymal sperm immunogenicity by boar seminal immunosuppressive component in mice by Dostal, J., Veselsky, L., Marounek, M., Zelezna, B., Jonakova, V.

“…Intravenous deposition of the immunosuppressive component, isolated from boar seminal vesicle secretion, led to suppression of primary and secondary antibody…”
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Ghrelin agonists impact on Fos protein expression in brain areas related to food intake regulation in male C57BL/6 mice by Pirnik, Z., Bundziková, J., Holubová, M., Pýchová, M., Fehrentz, J.A., Martinez, J., Železná, B., Maletínská, L., Kiss, A.

“…► We studied three ghrelin agonist analogs on Fos expression in different brain areas. ► Each of the ghrelin agonists induced strong food intake increase. ►…”
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Comparison of the obesity phenotypes related to monosodium glutamate effect on arcuate nucleus and/or the high fat diet feeding in C57BL/6 and NMRI mice by Matyšková, R, Maletínská, L, Maixnerová, J, Pirník, Z, Kiss, A, Železná, B

“…In this study, susceptibility of inbred C57BL/6 and outbred NMRI mice to monosodium glutamate (MSG) obesity or diet-induced obesity (DIO) was compared in terms…”
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Triazole GHS-R1a antagonists JMV4208 and JMV3002 attenuate food intake, body weight, and adipose tissue mass in mice by Holubová, M., Nagelová, V., Lacinová, Z., Haluzík, M., Sýkora, D., Moulin, A., Blayo, A.L., Fehrentz, J.A., Martinez, J., Stofkova, A., Jurčovičová, J., Železná, B., Maletínská, L.

“…•JMV4208 and JMV3002 decrease fasting-induced food intake in lean mice.•Both drugs promptly enter the blood stream and their half-life is 90 and 60min.•14-Day…”
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Changes in FGF21 serum concentrations and liver mRNA expression in an experimental model of complete lipodystrophy and insulin-resistant diabetes by Spolcová, A, Holubová, M, Mikulášková, B, Nagelová, V, Stofková, A, Lacinová, Z, Jurčovičová, J, Haluzík, M, Maletínská, L, Zelezná, B

“…Patients with obesity and type 2 diabetes often display high levels of the anti-diabetic factor fibroblast growth factor-21 (FGF21), suggesting that the…”
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Effects of Boar Seminal Immunosuppressive Fraction on Production of Cytokines by Concanavalin A-Stimulated Spleen Cells and on Proliferation of B Lymphoma Cell Lines by VESELSKY, L, HOLAN, V, ZAJICOVA, A, DOSTAL, J, ZELEZNA, B

“…PROBLEM:  The immunosuppressive fraction (ISF) of boar seminal vesicle fluid has recently been demonstrated to inhibit mitogen‐stimulated proliferation of…”
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Suppression of adjuvant arthritis in rats by boar seminal immunosuppressive fraction by VESELSKY, L, ZELEZNA, B, DOSTAL, J, STANCIKOVA, M, SVIK, K, ROKYTA, R, JURCOVICOVA, J

“…The effect of the immunosuppressive fraction of boar seminal vesicle fluid (ISF) was tested on the manifestation of adjuvant arthritis (AA) in rats. The…”
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Ghrelin agonist JMV 1843 increases food intake, body weight and expression of orexigenic neuropeptides in mice by Holubová, M, Spolcová, A, Demianová, Z, Sýkora, D, Fehrentz, J A, Martinez, J, Stofková, A, Jurčovičová, J, Drápalová, J, Lacinová, Z, Haluzík, M, Zelezná, B, Maletínská, L

“…Ghrelin and agonists of its receptor GHS-R1a are potential substances for the treatment of cachexia. In the present study, we investigated the acute and long…”
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Reaction Sequence and Molecular Mass of a Cl--Translocating P-Type ATPase by Gerencser, George A., Zelezna, Blanka

“…The basolateral membranes of Aplysia californica foregut absorptive cells contain both Cl--stimulated ATPase and ATP-dependent Cl-transport activities, and…”
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Effect of boar seminal immunosuppressive fraction on B lymphocytes and on primary antibody response by VESELSKY, L, DOSTAL, J, HOLAN, V, SOUCEK, J, ZELEZNA, B

“…Repeated i.p. or rectal treatment of male and female mice with an immunosuppressive component isolated from boar seminal vesicle secretion reduced responses of…”
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Direct evidence for an angiotensin AT1 receptor type in rat vas deferens by MALETINSKA, L, SLANINOVA, J, KUNES, J, ZELEZNA, B

“…Physiological experiments suggest that the angiotensin AT1 receptor type predominates in rat vas deferens. Membrane binding experiments, using…”
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