Search Results - "ZEITELS, Lauren"

An Essential Mesenchymal Function for miR-143/145 in Intestinal Epithelial Regeneration by Chivukula, Raghu R., Shi, Guanglu, Acharya, Asha, Mills, Eric W., Zeitels, Lauren R., Anandam, Joselin L., Abdelnaby, Abier A., Balch, Glen C., Mansour, John C., Yopp, Adam C., Maitra, Anirban, Mendell, Joshua T.

“…Downregulation of the miR-143/145 microRNA (miRNA) cluster has been repeatedly reported in colon cancer and other epithelial tumors. In addition,…”
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Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation by Chang, Tsung-Cheng, Zeitels, Lauren R, Hwang, Hun-Way, Chivukula, Raghu R, Wentzel, Erik A, Dews, Michael, Jung, Jason, Gao, Ping, Dang, Chi V, Beer, Michael A, Thomas-Tikhonenko, Andrei, Mendell, Joshua T

“…Direct control of microRNA (miRNA) expression by oncogenic and tumor suppressor networks results in frequent dysregulation of miRNAs in cancer cells and…”
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Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesis by Zeitels, Lauren R, Acharya, Asha, Shi, Guanglu, Chivukula, Divya, Chivukula, Raghu R, Anandam, Joselin L, Abdelnaby, Abier A, Balch, Glen C, Mansour, John C, Yopp, Adam C, Richardson, James A, Mendell, Joshua T

“…Down-regulation of miR-26 family members has been implicated in the pathogenesis of multiple malignancies. In some settings, including glioma, however,…”
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Precise let-7 expression levels balance organ regeneration against tumor suppression by Wu, Linwei, Nguyen, Liem H, Zhou, Kejin, de Soysa, T Yvanka, Li, Lin, Miller, Jason B, Tian, Jianmin, Locker, Joseph, Zhang, Shuyuan, Shinoda, Gen, Seligson, Marc T, Zeitels, Lauren R, Acharya, Asha, Wang, Sam C, Mendell, Joshua T, He, Xiaoshun, Nishino, Jinsuke, Morrison, Sean J, Siegwart, Daniel J, Daley, George Q, Shyh-Chang, Ng, Zhu, Hao

“…The in vivo roles for even the most intensely studied microRNAs remain poorly defined. Here, analysis of mouse models revealed that let-7, a large and ancient…”
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Association of the Vitamin D Metabolism Gene CYP27B1 With Type 1 Diabetes by BAILEY, Rebecca, COOPER, Jason D, NEJENTSEV, Sergey, TODD, John A, ZEITELS, Lauren, SMYTH, Deborah J, YANG, Jennie H. M, WALKER, Neil M, HYPPÖNEN, Elina, DUNGER, David B, RAMOS-LOPEZ, Elizabeth, BADENHOOP, Klaus

“…Association of the Vitamin D Metabolism Gene CYP27B1 With Type 1 Diabetes Rebecca Bailey 1 , Jason D. Cooper 1 , Lauren Zeitels 1 , Deborah J. Smyth 1 , Jennie…”
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When 19 is greater than 92 by Zeitels, Lauren R, Mendell, Joshua T

“…The gene miR-17-92 encodes six different microRNAs, with one of these acting as an internal brake that opposes the oncogenic activity of the others in some…”
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MCP-1 promoter variant −362C associated with protection from pulmonary tuberculosis in Ghana, West Africa by Thye, Thorsten, Nejentsev, Sergey, Intemann, Christopher D., Browne, Edmund N., Chinbuah, Margaret Amanua, Gyapong, John, Osei, Ivy, Owusu-Dabo, Ellis, Zeitels, Lauren R., Herb, Florian, Horstmann, Rolf D., Meyer, Christian G.

“…Current endeavour focuses on human genetic factors that contribute to susceptibility to or protection from tuberculosis (TB). Monocytes are crucial in…”
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The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes by Cooper, Jason D, Smyth, Deborah J, Bailey, Rebecca, Payne, Felicity, Downes, Kate, Godfrey, Lisa M, Masters, Jennifer, Zeitels, Lauren R, Vella, Adrian, Walker, Neil M, Todd, John A

“…As genes associated with immune-mediated diseases have an increased prior probability of being associated with other immune-mediated diseases, we tested three…”
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Factors influencing patient preferences for oral versus intravenous (IV) enzyme replacement medication by Karaa, Amel, Zeitels, Lauren, Clarke, Virginia

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Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes by Todd, John A, Walker, Neil M, Cooper, Jason D, Smyth, Deborah J, Downes, Kate, Plagnol, Vincent, Bailey, Rebecca, Nejentsev, Sergey, Field, Sarah F, Payne, Felicity, Lowe, Christopher E, Szeszko, Jeffrey S, Hafler, Jason P, Zeitels, Lauren, Yang, Jennie H M, Vella, Adrian, Nutland, Sarah, Stevens, Helen E, Schuilenburg, Helen, Coleman, Gillian, Maisuria, Meeta, Meadows, William, Smink, Luc J, Healy, Barry, Burren, Oliver S, Lam, Alex A C, Ovington, Nigel R, Allen, James, Adlem, Ellen, Leung, Hin-Tak, Wallace, Chris, Howson, Joanna M M, Guja, Cristian, Ionescu-Tîrgovi te, Constantin, Simmonds, Matthew J, Heward, Joanne M, Gough, Stephen C L, Dunger, David B, Wicker, Linda S, Clayton, David G

“…The Wellcome Trust Case Control Consortium (WTCCC) primary genome-wide association (GWA) scan on seven diseases, including the multifactorial autoimmune…”
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The Regulation and Function of miR-26 in Normal Physiology and Tumorigenesis by Zeitels, Lauren Rachel

“…It has become increasingly clear that the dysregulation of microRNAs (miRNAs), small (18-21nt) noncoding RNAs, plays an integral role in both normal physiology…”
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