Search Results - "ZEISIG, R"

Impact of intratumoral heterogeneity of renal cancer on drug response and development of resistance in patient derived xenografts by Zeisig, R, Flechsig, S, Wulf-Goldenberg, A, Schmees, C, Jandrig, B, Hennenlotter, J, Bedke, J, Stenzl, A, Schostak, M, Becker, M, Fichtner, I, Hoffmann, J

“…Background: Patients with advanced renal cell carcinoma (RCC) have a poor prognosis due to fast onset of resistance towards Standard of Care (SoC) drugs…”
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In vivo models for endocrine-dependent breast carcinomas : special considerations of clinical relevance by Fichtner, I, Becker, M, Zeisig, R, Sommer, A

“…Tumours in hormone-regulated organs such as the breast, prostate or ovaries are among the most frequent malignancies. Because of their endocrine-dependent…”
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Blocking of integrin-mediated human MV3 melanoma cell binding by commercial and modified heparins by Schlesinger, M, Naggi, A, Torri, G, Zeisig, R, Alexander, M, Schmitz, P, Casu, B, Bendas, G

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429 Design and development of nanocarrier for efficient drug delivery into the brain by Orthmann, A, Zeisig, R, Fichtner, I

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Liposomal Bleomycin: Increased Therapeutic Activity and Decreased Pulmonary Toxicity in Mice by Arndt, D, Zeisig, R, Bechtel, D, Fichtner, I

“…Conventional and sterically stabilized liposomes derived from phosphatidylcholine or the antitumor agents, hexadecylphosphocholine and…”
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Sialyl Lewis(x)-liposomes as vehicles for site-directed, E-selectin-mediated drug transfer into activated endothelial cells by Stahn, R, Grittner, C, Zeisig, R, Karsten, U, Felix, S B, Wenzel, K

“…E-selectin, exclusively expressed on activated endothelial cells, is a potential target for site-directed delivery of agents. We and others have shown that…”
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THE INFLUENCE OF CHOLESTEROL AND CHARGE ON THE MEMBRANE DOMAINS OF ALKYLPHOSPHOLIPID LIPOSOMES AS STUDIED BY EPR by Koklic, T., Šentjurc, M., Zeisig, R.

“…ABSTRACT Alkylphospholipids are physiologically active derivatives of lipids effective in the treatment of breast cancer. Among them,…”
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The composition-dependent presence of free (micellar) alkylphospholipid in liposomal formulations of octadecyl-1,1-dimethyl-piperidino-4-yl-phosphate affects its cytotoxic activity in vitro by Zeisig, R, Müller, K, Maurer, N, Arndt, D, Fahr, A

“…This study was performed to investigate the effect of cholesterol content, surface charge and sterical stabilization on the physico-chemical properties of…”
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Pharmacokinetics of sterically stabilized hexadecylphosphocholine liposomes versus conventional liposomes and free hexadecylphosphocholine in tumor-free and human breast carcinoma bearing mice by ARNDT, D, ZEISIG, R, FICHTNER, I, TEPPKE, A. D, FAHR, A

“…The pharmacokinetics of free and different liposomal formulations of hexadecylphosphocholine (HPC) was investigated in tumor-bearing (human mammary tumor MaTu)…”
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Sialyl Lewisx-liposomes as vehicles for site-directed, E-selectin-mediated drug transfer into activated endothelial cells by Stahn, R., Grittner, C., Zeisig, R., Karsten, U., Felix, S. B., Wenzel, K.

“…E-selectin, exclusively expressed on activated endothelial cells, is a potential target for site-directed delivery of agents. We and others have shown that…”
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Phospholipid- and fatty acid-composition in the erythrocyte membrane of the one-humped camel [Camelus dromedarius] and its influence on vesicle properties prepared from these lipids by Warda, M, Zeisig, R

“…The lipid composition of the membrane of erythrocytes from the one-humped camel (Camelus dromedarius) concerning the different lipid classes and the fatty…”
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Antineoplastic activity of sterically stabilized alkylphosphocholine liposomes in human breast carcinomas by ARNDT, D, ZEISIG, R, EUE, I, STERNBERG, B, FICHTNER, I

“…New sterically stabilized liposomes derived from the antitumor agent hexadecylphosphocholine with reduced uptake by the mononuclear phagocyte system and…”
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Impact of intratumoral heterogeneity of renal cancer on drug response and development of resistance in patient derived xenografts by Bedke, J, Flechsig, S, Hennenlotter, J, Wulf-Goldenberg, A, Jandrig, A, Schostak, M, Becker, M, Fichtner, I, Zeisig, R, Hoffmann, J, Schmees, C, Stenzl, A

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Phospholipid analogues: side chain- and polar head group-dependent effects on phosphatidylcholine biosynthesis by Geilen, C C, Haase, A, Wieder, T, Arndt, D, Zeisig, R, Reutter, W

“…In recent studies we showed that the phospholipid analogue hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis by affecting the translocation of…”
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212 - Impact of intratumoral heterogeneity of renal cancer on drug response and development of resistance in patient derived xenografts by Zeisig, R., Flechsig, S., Wulf-Goldenberg, A., Schmees, C., Jandrig, B., Hennenlotter, J., Bedke, J., Stenzl, A., Schostak, M., Becker, M., Fichtner, I., Hoffmann, J.

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Cytotoxic effects of alkylphosphocholines or alkylphosphocholine-liposomes and macrophages on tumor cells by Zeisig, R, Jungmann, S, Fichtner, I, Daemen, T, Arndt, D

“…The influence of the alkylphosphocholines (APC) on macrophage activation to tumor cytotoxicity was investigated in vitro with both mouse peritoneal and rat…”
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Antitumor effects of alkylphosphocholines in different murine tumor models: use of liposomal preparations by Zeisig, R, Fichtner, I, Arndt, D, Jungmann, S

“…Hexadecylphosphocholine (HPC) and its analogs with a longer alkyl chain (C18 and C20) were examined for antineoplastic activity in the murine tumor models P388…”
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Antineoplastic activity of alkylphosphocholines (APC) in human breast carcinomas in vivo and in vitro ; use of liposomes by FICHTNER, I, ZEISIG, R, NAUNDORF, H, JUNGMANN, S, ASONGWE, G, DOUBLE, J. A, BIBBY, M. C

“…This study examines the in vitro and in vivo activity of alkylphosphocholines (APC) in experimental human breast carcinomas. Three analogs,…”
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Cancerostatic octadecylpiperidinoylphosphate liposomes: effect of composition on uptake by and toxicity to J774 mouse macrophage cells and MT1 breast cancer cells in vitro by Zeisig, R, Stahn, R, Teppke, A D, Arndt, D

“…Liposomes prepared from the cancerostatic octadecyl-(N,N-dimethylpiperidino-4-yl)-phosphate (OPP) were investigated in order to characterize the influence of…”
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Antineoplastic activity in vitro of free and liposomal alkylphosphocholines by Zeisig, R, Jungmann, S, Arndt, D, Schütt, A, Nissen, E

“…We investigated the liposome forming properties of three homologues of alkylphosphocholines: hexadecylphosphocholine (HPC), octadecylphosphocholine (OPC) and…”
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