Search Results - "ZEA, Arnold H"

Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients by KO, Jennifer S, ZEA, Arnold H, DREICER, Robert, BUKOWSKI, Ronald, FINKE, James H, RINI, Brian I, IRELAND, Joanna L, ELSON, Paul, COHEN, Peter, GOLSHAYAN, Ali, RAYMAN, Patricia A, WOOD, Laura, GARCIA, Jorge

“…Purpose: Immune dysfunction reported in renal cell carcinoma (RCC) patients may contribute to tumor progression. Myeloid-derived suppressor cells (MDSC)…”
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Arginase, Prostaglandins, and Myeloid-Derived Suppressor Cells in Renal Cell Carcinoma by Ochoa, Augusto C, Zea, Arnold H, Hernandez, Claudia, Rodriguez, Paulo C

“…Tumor-induced tolerance is a well-established phenomenon in cancer patients that can severely impair the therapeutic efficacy of immunotherapy. One mechanism…”
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Arginase-producing myeloid suppressor cells in renal cell carcinoma patients : A mechanism of tumor evasion by ZEA, Arnold H, RODRIGUEZ, Paulo C, MIER, James, OCHOA, Augusto C, ATKINS, Michael B, HERNANDEZ, Claudia, SIGNORETTI, Sabina, ZABALETA, Jovanny, MCDERMON, David, QUICENO, David, YOUMANS, Amanda, O'NEILL, Anne

“…Myeloid suppressor cells with high arginase activity are found in tumors and spleen of mice with colon and lung cancer. These cells, described as macrophages…”
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PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice by Ghonim, Mohamed A, Pyakurel, Kusma, Ibba, Salome V, Wang, Jeffrey, Rodriguez, Paulo, Al-Khami, Amir A, Lammi, Matthew R, Kim, Hogyoung, Zea, Arnold H, Davis, Christian, Okpechi, Samuel, Wyczechowska, Dorota, Al-Ghareeb, Kamel, Mansy, Moselhy S, Ochoa, Augusto, Naura, Amarjit S, Boulares, A Hamid

“…Our laboratory established a role for poly(ADP-ribose)polymerase (PARP) in asthma. To increase the clinical significance of our studies, it is imperative to…”
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Activation of the IL-2 Receptor in Podocytes: A Potential Mechanism for Podocyte Injury in Idiopathic Nephrotic Syndrome? by Zea, Arnold H, Stewart, Tyrus, Ascani, Jeannine, Tate, David J, Finkel-Jimenez, Beatriz, Wilk, Anna, Reiss, Krzysztof, Smoyer, William E, Aviles, Diego H

“…The renal podocyte plays an important role in maintaining the structural integrity of the glomerular basement membrane. We have previously reported that…”
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The High-Risk Human Papillomavirus E6 Oncogene Exacerbates the Negative Effect of Tryptophan Starvation on the Development of Chlamydia trachomatis by Sherchand, Shardulendra P, Ibana, Joyce A, Zea, Arnold H, Quayle, Alison J, Aiyar, Ashok

“…Chlamydia trachomatis is an obligate intracellular pathogen that requires specific essential nutrients from the host cell, one of which is the amino acid…”
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Influence of the tryptophan-indole-IFNγ axis on human genital Chlamydia trachomatis infection: role of vaginal co-infections by Aiyar, Ashok, Quayle, Alison J, Buckner, Lyndsey R, Sherchand, Shardulendra P, Chang, Theresa L, Zea, Arnold H, Martin, David H, Belland, Robert J

“…The natural history of genital Chlamydia trachomatis infections can vary widely; infections can spontaneously resolve but can also last from months to years,…”
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Inhibition of Indoleamine 2,3-Dioxygenase Activity by Levo-1-Methyl Tryptophan Blocks Gamma Interferon-Induced Chlamydia trachomatis Persistence in Human Epithelial Cells by IBANA, Joyce A, BELLAND, Robert J, ZEA, Arnold H, SCHUST, Danny J, NAGAMATSU, Takeshi, ABDELRAHMAN, Yasser M, TATE, David J, BEATTY, Wandy L, AIYAR, Ashok A, QUAYLE, Alison J

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Morphologic and molecular evaluation of Chlamydia trachomatis growth in human endocervix reveals distinct growth patterns by Lewis, Maria E, Belland, Robert J, AbdelRahman, Yasser M, Beatty, Wandy L, Aiyar, Ashok A, Zea, Arnold H, Greene, Sheila J, Marrero, Luis, Buckner, Lyndsey R, Tate, David J, McGowin, Chris L, Kozlowski, Pamela A, O'Brien, Michelle, Lillis, Rebecca A, Martin, David H, Quayle, Alison J

“…In vitro models of Chlamydia trachomatis growth have long been studied to predict growth in vivo. Alternative or persistent growth modes in vitro have been…”
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Toll-like receptor-2 expression is upregulated in antigen-presenting cells from patients with psoriatic arthritis: a pathogenic role for innate immunity? by CANDIA, Liliana, MARQUEZ, Javier, HERNANDEZ, Claudia, ZEA, Arnold H, ESPINOZA, Luis R

“…OBJECTIVE: To study Toll-like receptor-2 (TLR-2) and TLR-4 expression in antigen-presenting cells from patients with psoriatic arthritis (PsA). METHODS: We…”
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Post-exposure therapeutic efficacy of COX-2 inhibition against Burkholderia pseudomallei by Asakrah, Saja, Nieves, Wildaliz, Mahdi, Zaid, Agard, Mallory, Zea, Arnold H, Roy, Chad J, Morici, Lisa A

“…Burkholderia pseudomallei is a Gram-negative, facultative intracellular bacillus and the etiologic agent of melioidosis, a severe disease in Southeast Asia and…”
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Decreased Expression of CD3ζ and Nuclear Transcription Factor κB in Patients with Pulmonary Tuberculosis: Potential Mechanisms and Reversibility with Treatment by Zea, Arnold H., Culotta, Kirk S., Ali, Juzar, Mason, Carol, Park, Hae-Joon, Zabaleta, Jovanny, Garcia, Luis F., Ochoa, Augusto C.

“…BackgroundThe protective immune response against Mycobacterium tuberculosis relies both on antigen-presenting cells and on T lymphocytes. In patients with…”
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Optimal Transactivation by Epstein-Barr Nuclear Antigen 1 Requires the UR1 and ATH1 Domains by SINGH, Gyanendra, ARAS, Siddhesh, ZEA, Arnold H, KOOCHEKPOUR, Shahriar, AIYAR, Ashok

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Interferon-gamma-induced nitric oxide inhibits the proliferation of murine renal cell carcinoma cells by Tate, Jr, David J, Patterson, John R, Velasco-Gonzalez, Cruz, Carroll, Emily N, Trinh, Janie, Edwards, Daniel, Aiyar, Ashok, Finkel-Jimenez, Beatriz, Zea, Arnold H

“…Renal cell carcinoma (RCC) remains one of the most resistant tumors to systemic chemotherapy, radiotherapy, and immunotherapy. Despite great progress in…”
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Downregulation of protein S in patients with severe COVID-19 augments the prothrombotic state by Melancon, Devin, Nguyen, Tina, Pereira, Verima, Harman, Jarrod, Chatterjee, Sabyasachi, Zea, Arnold H., Majumder, Samarpan, Majumder, Rinku

“…•We present the novel finding that the anticoagulant, Protein S is significantly downregulated by COVID-19.•Downregulation of Protein S partly explains the…”
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Patient-Derived Xenografts as an Innovative Surrogate Tumor Model for the Investigation of Health Disparities in Triple Negative Breast Cancer by Matossian, Margarite D, Giardina, Alexandra A, Wright, Maryl K, Elliott, Steven, Loch, Michelle M, Nguyen, Khoa, Zea, Arnold H, Lau, Frank H, Moroz, Krzysztof, Riker, Adam I, Jones, Steven D, Martin, Elizabeth C, Bunnell, Bruce A, Miele, Lucio, Collins-Burow, Bridgette M, Burow, Matthew E

“…Despite a decline in overall incidence rates for cancer in the past decade, due in part to impressive advancements in both diagnosis and treatment, breast…”
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Serine deamination by human serine racemase synergizes with antibiotics to curtail the replication of Chlamydia trachomatis by Mott, Patricia D., Zea, Arnold H., Lewis, Jamiya, Mirzalieva, Oygul, Aiyar, Ashok A.

“…The obligate intracellular bacterium, Chlamydia trachomatis, has evolved to depend on its human host for many metabolites, including most amino acids and three…”
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Effect of arginase II on L-arginine depletion and cell growth in murine cell lines of renal cell carcinoma by Tate, Jr, David J, Vonderhaar, Derek J, Caldas, Yupanqui A, Metoyer, Toye, Patterson, 4th, John R, Aviles, Diego H, Zea, Arnold H

“…L-arginine is the common substrate for the two isoforms of arginase. Arginase I, highly expressed in the liver and arginase II mainly expressed in the kidney…”
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ISGylation is increased in the peripheral blood mononuclear cells derived from symptomatic COVID-19 patients by Schwartzenburg, Joshua, Reed, Ryan, Koul, Hari, Zea, Arnold H, Shellito, Judd, Miele, Lucio, Crabtree, Judy S, Desai, Shyamal

“…Cytokine-driven hyper inflammation has been identified as a critical factor behind poor outcomes in patients severely infected with SARS-CoV-2 virus. Notably,…”
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Obesity facilitated colon cancer progression is mediated by increased diacylglycerol o-acyltransferases 1 and 2 (DGAT1/2) levels by Ghimire, Jenisha, Collins, Morgan E., Snarski, Patricia, King, Angelle N., Ruiz, Emmanuelle, Iftikhar, Rida, Penrose, Harrison M., Moroz, Krzysztof, Rorison, Tyler, Baddoo, Melody, Naeem, Muhammad Anas, Zea, Arnold H., Magness, Scott T., Flemington, Erik F., Crawford, Susan E., Savkovic, Suzana D.

“…The obesity epidemic is associated with increased colon cancer progression. As lipid droplets (LDs) fuel tumor growth, we aim to determine the significance of…”
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