Search Results - "ZATZ, Roberto"

Inflammation in Renal Diseases: New and Old Players by Andrade-Oliveira, Vinicius, Foresto-Neto, Orestes, Watanabe, Ingrid Kazue Mizuno, Zatz, Roberto, Câmara, Niels Olsen Saraiva

“…Inflammation, a process intimately linked to renal disease, can be defined as a complex network of interactions between renal parenchymal cells and resident…”
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In Memoriam: Professor Marcello Marcondes by Jorgetti, Vanda, Zatz, Roberto

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Evaluation of glomerular sirtuin-1 and claudin-1 in the pathophysiology of nondiabetic focal segmental glomerulosclerosis by Lopes-Gonçalves, Guilherme, Costa-Pessoa, Juliana Martins, Pimenta, Ruan, Tostes, Ana Flavia, da Silva, Eloisa Martins, Ledesma, Felipe Lourenço, Malheiros, Denise Maria Avancini Costa, Zatz, Roberto, Thieme, Karina, Câmara, Niels Olsen Saraiva, Oliveira-Souza, Maria

“…Focal segmental glomerulosclerosis (FSGS) is the leading cause of nephrotic syndrome, which is characterized by podocyte injury. Given that the pathophysiology…”
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NF-κB System Is Chronically Activated and Promotes Glomerular Injury in Experimental Type 1 Diabetic Kidney Disease by Foresto-Neto, Orestes, Albino, Amanda Helen, Arias, Simone Costa Alarcon, Faustino, Viviane Dias, Zambom, Fernanda Florencia Fregnan, Cenedeze, Marcos Antonio, Elias, Rosilene Motta, Malheiros, Denise Maria Avancini Costa, Camara, Niels Olsen Saraiva, Fujihara, Clarice Kazue, Zatz, Roberto

“…High glucose concentration can activate TLR4 and NF-κB, triggering the production of proinflammatory mediators. We investigated whether the NF-κB pathway is…”
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FGF-23 as a Predictor of Renal Outcome in Diabetic Nephropathy by Titan, Silvia M, Zatz, Roberto, Graciolli, Fabiana G, dos Reis, Luciene M, Barros, Rui T, Jorgetti, Vanda, Moysés, Rosa M A

“…Fibroblast growth factor 23 (FGF-23) has emerged as a new factor in mineral metabolism in chronic kidney disease (CKD). An important regulator of phosphorus…”
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In memoriam: Professor Gerhard Malnic by Rebouças, Nancy Amaral, Zatz, Roberto, Helou, Claudia Maria de Barros

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1,5-Anhydroglucitol predicts CKD progression in macroalbuminuric diabetic kidney disease: results from non-targeted metabolomics by Tavares, Gesiane, Venturini, Gabriela, Padilha, Kallyandra, Zatz, Roberto, Pereira, Alexandre C., Thadhani, Ravi I., Rhee, Eugene P., Titan, Silvia M. O.

“…Introduction Metabolomics allows exploration of novel biomarkers and provides insights on metabolic pathways associated with disease. To date, metabolomics…”
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Renal Inflammation and Innate Immune Activation Underlie the Transition From Gentamicin-Induced Acute Kidney Injury to Renal Fibrosis by Albino, Amanda Helen, Zambom, Fernanda Florencia Fregnan, Foresto-Neto, Orestes, Oliveira, Karin Carneiro, Ávila, Victor Ferreira, Arias, Simone Costa Alarcon, Seguro, Antonio Carlos, Malheiros, Denise Maria Avancini Costa, Camara, Niels Olsen Saraiva, Fujihara, Clarice Kazue, Zatz, Roberto

“…Subjects recovering from acute kidney injury (AKI) are at risk of developing chronic kidney disease (CKD). The mechanisms underlying this transition are…”
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Altered KLOTHO and NF-κB-TNF-α Signaling Are Correlated with Nephrectomy-Induced Cognitive Impairment in Rats by Degaspari, Sabrina, Tzanno-Martins, Carmen Branco, Fujihara, Clarice Kazue, Zatz, Roberto, Branco-Martins, João Paulo, Viel, Tania Araujo, Buck, Hudson de Souza, Orellana, Ana Maria Marques, Böhmer, Ana Elisa, Lima, Larissa de Sá, Andreotti, Diana Zukas, Munhoz, Carolina Demarchi, Scavone, Cristoforo, Kawamoto, Elisa Mitiko

“…Renal insufficiency can have a negative impact on cognitive function. Neuroinflammation and changes in klotho levels associate with chronic kidney disease…”
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Pivotal role of Toll-like receptors 2 and 4, its adaptor molecule MyD88, and inflammasome complex in experimental tubule-interstitial nephritis by Correa-Costa, Matheus, Braga, Tarcio Teodoro, Semedo, Patricia, Hayashida, Caroline Yuri, Bechara, Luiz Roberto Grassmann, Elias, Rosa Maria, Barreto, Claudiene Rodrigues, Silva-Cunha, Claudia, Hyane, Meire Ioshie, Gonçalves, Giselle Martins, Brum, Patricia Chakur, Fujihara, Clarice, Zatz, Roberto, Pacheco-Silva, Alvaro, Zamboni, Dario S, Camara, Niels Olsen Saraiva

“…Tubule-interstitial nephritis (TIN) results in decreased renal function and interstitial inflammation, which ultimately leads to fibrosis. Excessive adenine…”
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The Protein-Independent Role of Phosphate in the Progression of Chronic Kidney Disease by Duayer, Irene Faria, Duque, Eduardo Jorge, Fujihara, Clarice Kazue, de Oliveira, Ivone Braga, Dos Reis, Luciene Machado, Machado, Flavia Gomes, Graciolli, Fabiana Giorgetti, Jorgetti, Vanda, Zatz, Roberto, Elias, Rosilene Motta, Moysés, Rosa Maria Affonso

“…Several factors contribute to renal-function decline in CKD patients, and the role of phosphate content in the diet is still a matter of debate. This study…”
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Innate And Adaptive Immunity are Progressively Activated in Parallel with Renal Injury in the 5/6 Renal Ablation Model by Fanelli, Camilla, Arias, Simone C. A., Machado, Flavia G., Okuma, Jessica K., Malheiros, Denise M. A. C., Azevedo, Hatylas, Moreira-Filho, Carlos A., Camara, Niels O. S., Fujihara, Clarice K., Zatz, Roberto

“…The mechanisms triggering renal inflammation in chronic kidney disease (CKD) are unclear. We performed a detailed analysis of the time course of innate and…”
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Regression of albuminuria and hypertension and arrest of severe renal injury by a losartan-hydrochlorothiazide association in a model of very advanced nephropathy by Arias, Simone Costa Alarcon, Valente, Carla Perez, Machado, Flavia Gomes, Fanelli, Camilla, Origassa, Clarice Silvia Taemi, de Brito, Thales, Camara, Niels Olsen Saraiva, Malheiros, Denise Maria Avancini Costa, Zatz, Roberto, Fujihara, Clarice Kazue

“…Treatments that effectively prevent chronic kidney disease (CKD) when initiated early often yield disappointing results when started at more advanced phases…”
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Pathogenic role of angiotensin II and the NF-κB system in a model of malignant hypertensive nephrosclerosis by Ávila, Victor F, Foresto-Neto, Orestes, Arias, Simone C A, Faustino, Viviane D, Malheiros, Denise M A C, Camara, Niels O S, Zatz, Roberto, Fujihara, Clarice K

“…We previously reported that rats treated with an NF-κB inhibitor, pyrrolidine dithiocarbamate (PDTC), during lactation developed hypertension in adult life,…”
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A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy by Fujihara, Clarice K., Kowala, M. C., Breyer, M. D., Sena, Claudia R., Rodrigues, Mariliza V., Arias, Simone C. A., Fanelli, Camilla, Malheiros, Denise M., Jadhav, P. K., Montrose-Rafizadeh, Chahrzad, Krieger, Jose E., Zatz, Roberto

“…Aldosterone antagonists slow the progression of chronic kidney disease (CKD), but their use is limited by hyperkalemia, especially when associated with RAS…”
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Influence of low free thyroxine on progression of chronic kidney disease by de Souza, Alexandre Barbosa Câmara, Arantes, Marcia Fernanda, Zatz, Roberto, Elias, Rosilene Motta, Lopes, Roberto Iglesias, Macedo, Etienne

“…Hypothyroidism is highly prevalent in patients with chronic kidney disease (CKD) and has been associated with poorer clinical outcomes, including faster…”
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Renal and Myocardial Histopathology and Morphometry in Rats with Adenine - Induced Chronic Renal Failure: Influence of Gum Acacia by Ali, Badreldin H., Inuwa, Ibrahim, Al Za'abi, Mohamed, Al Bahlani, Shadia, Al Issaei, Halima, Ramkumar, Aishwarya, Madanagopal, Thulasi, Nemmar, Abedrrahim, Malheiros, Denise M., Zatz, Roberto

“…Background/Aim: Chronic kidney disease (CKD) is associated with increased occurrence of cardiovascular system dysfunction. Previous studies have revealed a…”
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Sustained kidney biochemical derangement in treated experimental diabetes: a clue to metabolic memory by de Oliveira, Antonio Anax F., de Oliveira, Tiago F., Bobadilla, Larissa L., Garcia, Camila C. M., Berra, Carolina Maria, de Souza-Pinto, Nadja C., Medeiros, Marisa H. G., Di Mascio, Paolo, Zatz, Roberto, de M. Loureiro, Ana Paula

“…The occurrence of biochemical alterations that last for a long period of time in diabetic individuals even after adequate handling of glycemia is an intriguing…”
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Design and methodology of the Aging Nephropathy Study (AGNES): a prospective cohort study of elderly patients with chronic kidney disease by Coelho, Venceslau A, Santos, Giovani Gn, Avesani, Carla M, Bezerra, Cicero Italo L, Silva, Luana Cristina A, Lauar, Julia C, Lindholm, Bengt, Stenvinkel, Peter, Jacob-Filho, Wilson, Noronha, Irene L, Zatz, Roberto, Moysés, Rosa M A, Elias, Rosilene M

“…Renal replacement therapy (RRT) is usually indicated for patients with chronic kidney disease (CKD) with glomerular filtration rate below 10 ml/ml/min/1.73m …”
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Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth of murine melanoma by Otake, Andréia Hanada, Mattar, Ana Lucia, Freitas, Helano Carioca, Machado, Camila Maria Longo, Nonogaki, Suely, Fujihara, Clarice Kazue, Zatz, Roberto, Chammas, Roger

“…Purpose We evaluated the involvement of angiotensin II (AngII)-dependent pathways in melanoma growth, through the pharmacological blockage of AT1 receptor by…”
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