Search Results - "ZARKOVIC, Kamelija"

Contribution of the HNE-immunohistochemistry to modern pathological concepts of major human diseases by Zarkovic, Kamelija, Jakovcevic, Antonia, Zarkovic, Neven

“…Excessive production of reactive oxygen species can induce peroxidation of the polyunsaturated fatty acids thus generating reactive aldehydes like…”
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The relevance of pathophysiological alterations in redox signaling of 4-hydroxynonenal for pharmacological therapies of major stress-associated diseases by Jaganjac, Morana, Milkovic, Lidija, Gegotek, Agnieszka, Cindric, Marina, Zarkovic, Kamelija, Skrzydlewska, Elzbieta, Zarkovic, Neven

“…Modern analytical methods combined with the modern concepts of redox signaling revealed 4-hydroxy-2-nonenal (4-HNE) as particular growth regulating factor…”
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Pathophysiological relevance of aldehydic protein modifications by Zarkovic, Neven, Cipak, Ana, Jaganjac, Morana, Borovic, Suzana, Zarkovic, Kamelija

“…There is growing body of evidence that oxidative stress, i.e. excess in production of reactive oxygen species, can lead to covalent modification of proteins…”
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Biomarkers of oxidative and nitro‐oxidative stress: conventional and novel approaches by Cipak Gasparovic, Ana, Zarkovic, Neven, Zarkovic, Kamelija, Semen, Khrystyna, Kaminskyy, Danylo, Yelisyeyeva, Olha, Bottari, Serge P.

“…The concept of oxidative stress (OS) that connects altered redox biology with various diseases was introduced 30 years ago and has generated intensive research…”
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The 4-Hydroxynonenal-Protein Adducts and Their Biological Relevance: Are Some Proteins Preferred Targets? by Milkovic, Lidija, Zarkovic, Neven, Marusic, Zlatko, Zarkovic, Kamelija, Jaganjac, Morana

“…It is well known that oxidative stress and lipid peroxidation (LPO) play a role in physiology and pathology. The most studied LPO product with pleiotropic…”
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SFRP4 protein expression is reduced in high grade astrocytomas which is not caused by the methylation of its promoter by Kafka, Anja, Pećina-Šlaus, Nives, Drmić, Denis, Bukovac, Anja, Njirić, Niko, Žarković, Kamelija, Jakovčević, Antonia

“…Epigenetics play a vital role in stratifying CNS tumors and gliomas. The importance of studying Secreted frizzled-related protein 4 (SFRP4) in gliomas is to…”
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The Appearance of 4-Hydroxy-2-Nonenal (HNE) in Squamous Cell Carcinoma of the Oropharynx by Jakovčević, Antonia, Žarković, Kamelija, Jakovčević, Danica, Rakušić, Zoran, Prgomet, Drago, Waeg, Georg, Šunjić, Suzana Borović, Žarković, Neven

“…Tumor growth is associated with oxidative stress, which causes lipid peroxidation. The most intensively studied product of lipid peroxidation is…”
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4-Hydroxynonenal Modulates Blood-Brain Barrier Permeability In Vitro through Changes in Lipid Composition and Oxidative Status of Endothelial Cells and Astrocytes by Cindrić, Marina, Čipak Gašparović, Ana, Milković, Lidija, Bujak, Ivana Tartaro, Mihaljević, Branka, Žarković, Neven, Žarković, Kamelija

“…Blood brain barrier (BBB) is a dynamic interface responsible for proper functioning of brain, but also a major obstacle for effective treatment of neurological…”
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Preliminary Findings on the Association of the Lipid Peroxidation Product 4-Hydroxynonenal with the Lethal Outcome of Aggressive COVID-19 by Žarković, Neven, Orehovec, Biserka, Milković, Lidija, Baršić, Bruno, Tatzber, Franz, Wonisch, Willibald, Tarle, Marko, Kmet, Marta, Mataić, Ana, Jakovčević, Antonia, Vuković, Tea, Talić, Danijela, Waeg, Georg, Lukšić, Ivica, Skrzydlewska, Elzbieta, Žarković, Kamelija

“…Major findings of the pilot study involving 21 critically ill patients during the week after admission to the critical care unit specialized for COVID-19 are…”
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Lipid mediators involved in the oxidative stress and antioxidant defence of human lung cancer cells by Gęgotek, Agnieszka, Nikliński, Jacek, Žarković, Neven, Žarković, Kamelija, Waeg, Georg, Łuczaj, Wojciech, Charkiewicz, Radosław, Skrzydlewska, Elżbieta

“…The oxidative modifications of bioactive macromolecules have important roles in carcinogenesis. Of particular interest are lipid peroxidation products, which…”
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Advances in methods for the determination of biologically relevant lipid peroxidation products by Spickett, Corinne M, Wiswedel, Ingrid, Siems, Werner, Zarkovic, Kamelija, Zarkovic, Neven

“…Lipid peroxidation is recognized to be an important contributor to many chronic diseases, especially those of an inflammatory pathology. In addition to their…”
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Overview of the Lipid Peroxidation Measurements in Patients by the Enzyme-Linked Immunosorbent Assay Specific for the 4-Hydroxynonenal-Protein Adducts (4-HNE-ELISA) by Žarković, Neven, Gęgotek, Agnieszka, Łuczaj, Wojciech, Jaganjac, Morana, Šunjić, Suzana Borović, Žarković, Kamelija, Skrzydlewska, Elzbieta

“…Oxidative stress often affects the structure and metabolism of lipids, which in the case of polyunsaturated free fatty acids (PUFAs) leads to a self-catalysed…”
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Post-mortem Findings of Inflammatory Cells and the Association of 4-Hydroxynonenal with Systemic Vascular and Oxidative Stress in Lethal COVID-19 by Zarkovic, Neven, Jakovcevic, Antonia, Mataic, Ana, Jaganjac, Morana, Vukovic, Tea, Waeg, Georg, Zarkovic, Kamelija

“…A recent comparison of clinical and inflammatory parameters, together with biomarkers of oxidative stress, in patients who died from aggressive COVID-19 and…”
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Different behaviour of DVL1, DVL2, DVL3 in astrocytoma malignancy grades and their association to TCF1 and LEF1 upregulation by Kafka, Anja, Bačić, Mateja, Tomas, Davor, Žarković, Kamelija, Bukovac, Anja, Njirić, Niko, Mrak, Goran, Krsnik, Željka, Pećina‐Šlaus, Nives

“…Key regulators of the Wnt signalling, DVL1, DVL2 and DVL3, in astrocytomas of different malignancy grades were investigated. Markers for DVL1, DVL2 and DVL3…”
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Relationship between 4-Hydroxynonenal (4-HNE) as Systemic Biomarker of Lipid Peroxidation and Metabolomic Profiling of Patients with Prostate Cancer by Perkovic, Matea Nikolac, Jaganjac, Morana, Milkovic, Lidija, Horvat, Tea, Rojo, David, Zarkovic, Kamelija, Ćorić, Marijana, Hudolin, Tvrtko, Waeg, Georg, Orehovec, Biserka, Zarkovic, Neven

“…An oxidative degradation product of the polyunsaturated fatty acids, 4-hydroxynonenal (4-HNE), is of particular interest in cancer research due to its…”
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Foam cell‐derived 4‐hydroxynonenal induces endothelial cell senescence in a TXNIP‐dependent manner by Riahi, Yael, Kaiser, Nurit, Cohen, Guy, Abd‐Elrahman, Ihab, Blum, Galia, Shapira, Oz M., Koler, Tomer, Simionescu, Maya, Sima, Anca V., Zarkovic, Neven, Zarkovic, Kamelija, Orioli, Marica, Aldini, Giancarlo, Cerasi, Erol, Leibowitz, Gil, Sasson, Shlomo

“…Vascular endothelial cell (VEC) senescence is considered an early event in the development of atherosclerotic lesions. Stressful stimuli, in particular…”
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Association between aryl hydrocarbon receptor and 4-hydroxynonenal in oxidative stress-mediated chronic rhinosinusitis with nasal polyps by Kvarantan, Aigerim, Balta, Vedran, Zarkovic, Neven, Horvat, Tea, Vukovic, Tea, Zarkovic, Kamelija, Kalogjera, Livije

“…Objective Сhronic rhinosinusitis with nasal polyps (CRSwNPs) is a distinct entity within the chronic rhinosinusitis group of diseases, which are chronic upper…”
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Elastin aging and lipid oxidation products in human aorta by Zarkovic, Kamelija, Larroque-Cardoso, Pauline, Pucelle, Mélanie, Salvayre, Robert, Waeg, Georg, Nègre-Salvayre, Anne, Zarkovic, Neven

“…Vascular aging is associated with structural and functional modifications of the arteries, and by an increase in arterial wall thickening in the intima and the…”
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Methylation Patterns of DKK1, DKK3 and GSK3β Are Accompanied with Different Expression Levels in Human Astrocytoma by Kafka, Anja, Bukovac, Anja, Brglez, Emilija, Jarmek, Ana-Marija, Poljak, Karolina, Brlek, Petar, Žarković, Kamelija, Njirić, Niko, Pećina-Šlaus, Nives

“…In the present study, we investigated genetic and epigenetic changes and protein expression levels of negative regulators of Wnt signaling, DKK1, DKK3, and APC…”
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Positron emission tomography-computed tomography and 4-hydroxynonenal-histidine immunohistochemistry reveal differential onset of lipid peroxidation in primary lung cancer and in pulmonary metastasis of remote malignancies by Živković, Nevenka Piskač, Petrovečki, Mladen, Lončarić, Čedna Tomasović, Nikolić, Igor, Waeg, Georg, Jaganjac, Morana, Žarković, Kamelija, Žarković, Neven

“…The Aim of the study was to reveal if PET-CT analysis of primary and of secondary lung cancer could be related to the onset of lipid peroxidation in cancer and…”
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