Search Results - "ZAMB, Timothy"

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target by Walker, Laura M, Phogat, Sanjay K, Chan-Hui, Po-Ying, Wagner, Denise, Phung, Pham, Goss, Julie L, Wrin, Terri, Simek, Melissa D, Fling, Steven, Mitcham, Jennifer L, Lehrman, Jennifer K, Priddy, Frances H, Olsen, Ole A, Frey, Steven M, Hammond, Phillip W, Kaminsky, Stephen, Zamb, Timothy, Moyle, Matthew, Koff, Wayne C, Poignard, Pascal, Burton, Dennis R

“…Broadly neutralizing antibodies (bNAbs), which develop over time in some HIV-1-infected individuals, define critical epitopes for HIV vaccine design. Using a…”
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Enhanced Control of Pathogenic Simian Immunodeficiency Virus SIVmac239 Replication in Macaques Immunized with an Interleukin-12 Plasmid and a DNA Prime-Viral Vector Boost Vaccine Regimen by Winstone, Nicola, Wilson, Aaron J, Morrow, Gavin, Boggiano, Cesar, Chiuchiolo, Maria J, Lopez, Mary, Kemelman, Marina, Ginsberg, Arielle A, Mullen, Karl, Coleman, John W, Wu, Chih-Da, Narpala, Sandeep, Ouellette, Ian, Dean, Hansi J, Lin, Feng, Sardesai, Niranjan Y, Cassamasa, Holly, McBride, Dawn, Felber, Barbara K, Pavlakis, George N, Schultz, Alan, Hudgens, Michael G, King, C. Richter, Zamb, Timothy J, Parks, Christopher L, McDermott, Adrian B

“…DNA priming has previously been shown to elicit augmented immune responses when administered by electroporation (EP) or codelivered with a plasmid encoding…”
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HIV vaccine design: insights from live attenuated SIV vaccines by Koff, Wayne C, Johnson, Philip R, Watkins, David I, Burton, Dennis R, Lifson, Jeffrey D, Hasenkrug, Kim J, McDermott, Adrian B, Schultz, Alan, Zamb, Timothy J, Boyle, Rosanne, Desrosiers, Ronald C

“…The International AIDS Vaccine Initiative has established a consortium to elucidate mechanisms of protection conferred by live attenuated simian…”
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Neurovirulence and immunogenicity of attenuated recombinant vesicular stomatitis viruses in nonhuman primates by Clarke, David K, Nasar, Farooq, Chong, Siew, Johnson, J Erik, Coleman, John W, Lee, Margaret, Witko, Susan E, Kotash, Cheryl S, Abdullah, Rashed, Megati, Shakuntala, Luckay, Amara, Nowak, Becky, Lackner, Andrew, Price, Roger E, Little, Peter, Kalyan, Narender, Randolf, Valerie, Javadian, Ali, Zamb, Timothy J, Parks, Christopher L, Egan, Michael A, Eldridge, John, Hendry, Michael, Udem, Stephen A

“…In previous work, a prototypic recombinant vesicular stomatitis virus Indiana serotype (rVSIV) vector expressing simian immunodeficiency virus (SIV) gag and…”
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Development of a duplex real-time RT-qPCR assay to monitor genome replication, gene expression and gene insert stability during in vivo replication of a prototype live attenuated canine distemper virus vector encoding SIV gag by Coleman, John W., Wright, Kevin J., Wallace, Olivia L., Sharma, Palka, Arendt, Heather, Martinez, Jennifer, DeStefano, Joanne, Zamb, Timothy P., Zhang, Xinsheng, Parks, Christopher L.

“…•The duplex assay monitored replication, tissue distribution, and mRNA expression.•The duplex assay monitored insert genetic stability during in vivo…”
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Membrane-bound SIV envelope trimers are immunogenic in ferrets after intranasal vaccination with a replication-competent canine distemper virus vector by Zhang, Xinsheng, Wallace, Olivia, Wright, Kevin J, Backer, Martin, Coleman, John W, Koehnke, Rebecca, Frenk, Esther, Domi, Arban, Chiuchiolo, Maria J, DeStefano, Joanne, Narpala, Sandeep, Powell, Rebecca, Morrow, Gavin, Boggiano, Cesar, Zamb, Timothy J, Richter King, C, Parks, Christopher L

“…Abstract We are investigating canine distemper virus (CDV) as a vaccine vector for the delivery of HIV envelope (Env) that closely resembles the native…”
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The stem of vesicular stomatitis virus G can be replaced with the HIV-1 Env membrane-proximal external region without loss of G function or membrane-proximal external region antigenic properties by Lorenz, Ivo C, Nguyen, Hanh T, Kemelman, Marina, Lindsay, Ross W, Yuan, Maoli, Wright, Kevin J, Arendt, Heather, Back, Jaap Willem, DeStefano, Joanne, Hoffenberg, Simon, Morrow, Gavin, Jurgens, Christy K, Phogat, Sanjay K, Zamb, Timothy J, Parks, Christopher L

“…The structure of the HIV-1 envelope membrane-proximal external region (MPER) is influenced by its association with the lipid bilayer on the surface of virus…”
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Corrigendum to “Membrane-bound SIV envelope trimmers are immunogenic in ferrets after intranasal vaccination with a replication-competent canine distemper virus vector” [Virology 446 (2013) 25–36] by Zhang, Xinsheng, Wallace, Olivia, Wright, Kevin J, Backer, Martin, Coleman, John W, Koehnke, Rebecca, Frenk, Esther, Domi, Arban, Chiuchiolo, Maria J, DeStefano, Joanne, Narpala, Sandeep, Powell, Rebecca, Morrow, Gavin, Boggiano, Cesar, Zamb, Timothy J, Richter King, C, Parks, Christopher L

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Genetic and phenotypic stability of cold-adapted influenza viruses in a trivalent vaccine administered to children in a day care setting by Buonagurio, Deborah A., O'Neill, Robert E., Shutyak, Leonid, D'Arco, Gail A., Bechert, Thomas M., Kazachkov, Yuriy, Wang, Hai-Ping, DeStefano, Joanne, Coelingh, Kathleen L., August, Marilyn, Parks, Christopher L., Zamb, Timothy J., Sidhu, Mohinder S., Udem, Stephen A.

“…The genetic and phenotypic stability of viruses isolated from young children following intranasal administration of the trivalent live-attenuated influenza…”
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Herpes Simplex Virus Type 2 UL24 Gene Is a Virulence Determinant in Murine and Guinea Pig Disease Models by BLAKENEY, Susan, KOWALSKI, Jacek, VISALLI, Robert J, TUMMOLO, Donna, DESTEFANO, Joanne, COOPER, David, MIN GUO, GANGOLLI, Seema, LONG, Deborah, ZAMB, Timothy, NATUK, Robert J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Genetic stability of live, cold-adapted influenza virus components of the FluMist ®/CAIV-T vaccine throughout the manufacturing process by Buonagurio, Deborah A., Bechert, Thomas M., Yang, Chin-Fen, Shutyak, Leonid, D’Arco, Gail A., Kazachkov, Yuriy, Wang, Hai-Ping, Rojas, Eduardo A., O’Neill, Robert E., Spaete, Richard R., Coelingh, Kathleen L., Zamb, Timothy J., Sidhu, Mohinder S., Udem, Stephen A.

“…FluMist ® is a live-attenuated, trivalent influenza vaccine (LAIV) recently approved for intranasal administration. To demonstrate genetic stability during…”
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Phenotypic properties resulting from directed gene segment reassortment between wild-type A/Sydney/5/97 influenza virus and the live attenuated vaccine strain by Parks, Christopher L, Latham, Theresa, Cahill, Adriana, O'Neill, Robert E, Passarotti, Christopher J, Buonagurio, Deborah A, Bechert, Thomas M, D'Arco, Gail A, Neumann, Gabriele, DeStefano, Joanne, Arendt, Heather E, Obregon, Jennifer, Shutyak, Leonid, Hamm, Stefan, Sidhu, Mohinderjit S, Zamb, Timothy J, Udem, Stephen A

“…Abstract Widespread use of a live-attenuated influenza vaccine (LAIV) in the United States (licensed as FluMist) raises the possibility that vaccine viruses…”
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Quantitative multiplex assay for simultaneous detection of the Indiana serotype of vesicular stomatitis virus and HIV gag by Coleman, John W., Ogin-Wilson, Eleanor, Johnson, J. Erik, Nasar, Farooq, Zamb, Timothy P., Clarke, David K., Hendry, R. Michael, Udem, Stephen A.

“…Assessment of in vivo viral replication of live attenuated recombinant vesicular stomatitis virus (rVSV) vaccine vector candidates encoding HIV gag requires…”
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Corrigendum to “Phenotypic properties resulting from directed gene segment reassortment between wild-type A/Sydney/5/97 influenza virus and the live attenuated vaccine strain” [Virology 367 (2007) 275–287] by Parks, Christopher L, Latham, Theresa, Cahill, Adriana, O'Neill, Robert E, Passarotti, Christopher J, Buonagurio, Deborah A, Bechert, Thomas M, D'Arco, Gail A, Neumann, Gabriele, DeStefano, Joanne, Arendt, Heather E, Obregon, Jennifer, Shutyak, Leonid, Hamm, Stefan, Sidhu, Mohinderjit S, Zamb, Timothy J, Udem, Stephen A

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Synthetic luteinizing hormone releasing hormone (LHRH) vaccine for effective androgen deprivation and its application to prostate cancer immunotherapy by Finstad, Connie L, Wang, Chang Yi, Kowalski, Jacek, Zhang, Meilun, Li, Ming Lie, Li, Xuan Mao, Xia, Wei Guo, Bosland, Maarten C, Murthy, Krishna K, Walfield, Alan M, Koff, Wayne C, Zamb, Timothy J

“…We have designed a peptide-based immunotherapeutic vaccine for treatment of androgen-responsive prostate cancer. The vaccine targets the luteinizing…”
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Transfection-independent production of alphavirus replicon particles based on poxvirus expression vectors by Kovacs, Gerald R, Vasilakis, Nikos, Falvey, Darlene, Gangolli, Seema S, Coleman, John, Kowalski, Jacek, Udem, Stephen A, Zamb, Timothy J

“…This report describes a transfection-independent system for packaging alphavirus replicon vectors using modified vaccinia virus Ankara (MVA) vectors to express…”
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A modified cholera holotoxin CT-E29H enhances systemic and mucosal immune responses to recombinant Norwalk virus–virus like particle vaccine by Periwal, Sangeeta B, Kourie, Kristin R, Ramachandaran, Nandini, Blakeney, Susan J, DeBruin, Sylvia, Zhu, Duzhang, Zamb, Timothy J, Smith, Larry, Udem, Steve, Eldridge, John H, Shroff, Khushroo E, Reilly, Patricia A

“…In this study, we evaluated the potential of a genetically modified cholera toxin, CT-E29H as an adjuvant for recombinant Norwalk virus like particle (NV-VLP)…”
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A method of alphavirus replicon particle titration based on expression of functional replicase/transcriptase by Gangolli, Seema S., Vasilakis, Nikolaos, Kovacs, Gerald R., Zamb, Timothy J., Kowalski, Jacek

“…Alphavirus replicon particles are being exploited for a variety of purposes both in vitro as gene expression vectors, and in vivo as vaccines or gene therapy…”
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Crystal Structure of the Oligomerization Domain of NSP4 from Rotavirus Reveals a Core Metal-binding Site by Bowman, Gregory D., Nodelman, Ilana M., Levy, Orlie, Lin, Shuo L., Tian, Peng, Zamb, Timothy J., Udem, Stephen A., Venkataraghavan, Babu, Schutt, Clarence E.

“…During the maturation of rotaviral particles, non-structural protein 4 (NSP4) plays a critical role in the translocation of the immature capsid into the lumen…”
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Genetic stability of live, cold-adapted influenza virus components of the FluMist super([registered])/CAIV-T vaccine throughout the manufacturing process by Buonagurio, Deborah A, Bechert, Thomas M, Yang, Chin-Fen, Shutyak, Leonid, D'Arco, Gail A, Kazachkov, Yuriy, Wang, Hai-Ping, Rojas, Eduardo A, O'Neill, Robert E, Spaete, Richard R, Coelingh, Kathleen L, Zamb, Timothy J, Sidhu, Mohinder S, Udem, Stephen A

“…FluMist super([registered]) is a live-attenuated, trivalent influenza vaccine (LAIV) recently approved for intranasal administration. To demonstrate genetic…”
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