Search Results - "ZAKERI, ZAHRA"

Flavivirus NS4A-induced Autophagy Protects Cells against Death and Enhances Virus Replication by McLean, Jeffrey E., Wudzinska, Aleksandra, Datan, Emmanuel, Quaglino, Daniela, Zakeri, Zahra

“…Flaviviruses include the most prevalent and medically challenging viruses. Persistent infection with flaviviruses of epithelial cells and hepatocytes that do…”
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Atorvastatin restricts the ability of influenza virus to generate lipid droplets and severely suppresses the replication of the virus by Episcopio, Donna, Aminov, Sarah, Benjamin, Shawna, Germain, Gabrielle, Datan, Emmanuel, Landazuri, Joselyn, Lockshin, Richard A., Zakeri, Zahra

“…ABSTRACT Influenza virus causes infected cells to generate large numbers of lipid droplets. Because the virus envelope contains substantial cholesterol, we…”
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Andrew H. Wyllie, a pioneer in the field of apoptosis by Zakeri, Zahra, Lockshin, Richard A

“…Abstract We mourn, and briefly describe the life and contributions of, Andrew H. Wyllie, who was a co-author of the first paper to describe apoptosis, and a…”
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Association of P2X7 receptor genetic polymorphisms and expression with rheumatoid arthritis susceptibility in a sample of the Iranian population: a case-control study by Bahari, Gholamreza, Tabasi, Farhad, Hashemi, Mohammad, Zakeri, Zahra, Taheri, Mohsen

“…Objective Rheumatoid arthritis (RA) is a complex inflammatory autoimmune disease with joint eruption, systemic manifestation, and numerous predisposing genetic…”
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Cell death in health and disease by Lockshin, Richard A, Zakeri, Zahra

“…•  Cell death is important in medicine •  Why do we not have a medicine based on apoptosis? •  The machinery of cell death •  Cells have many options other…”
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Ceramide from sphingomyelin hydrolysis induces neuronal differentiation, whereas de novo ceramide synthesis and sphingomyelin hydrolysis initiate apoptosis after NGF withdrawal in PC12 Cells by Kagan, Terri, Stoyanova, Gloria, Lockshin, Richard A, Zakeri, Zahra

“…Ceramide, important for both neuronal differentiation and dedifferentiation, resides in several membranes, is synthesized in the endoplasmic reticulum,…”
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Lack of Bax Prevents Influenza A Virus-Induced Apoptosis and Causes Diminished Viral Replication by MCLEAN, Jeffrey E, DATAN, Emmanuel, MATASSOV, Demetrius, ZAKERI, Zahra F

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Zika virus triggers autophagy to exploit host lipid metabolism and drive viral replication by Stoyanova, Gloria, Jabeen, Sidra, Landazuri Vinueza, Joselyn, Ghosh Roy, Sounak, Lockshin, Richard A, Zakeri, Zahra

“…Zika virus (ZIKV), an arbovirus of global concern, has been associated with neurological complications including microcephaly in newborns and Guillain-Barré…”
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4‐{3‐[(Pyridin‐4‐ylmethyl)amino]‐[1,2,4]triazolo[4,3‐b][1,2,4]triazin‐6‐yl}phenol: An improved anticancer agent in hepatocellular carcinoma and a selective MDR1/MRP modulator by Khatir, Zahra Zakeri, Di Sotto, Antonella, Percaccio, Ester, Tuylu Kucukkilinc, Tuba, Ercan, Ayse, Chippindale, Ann M., Valipour, Mehdi, Irannejad, Hamid

“…Hepatocellular carcinoma is the most common type of primary liver cancer. However, multidrug resistance (MDR) is a major obstacle to the effective chemotherapy…”
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Reduced sperm telomere length in individuals with varicocele is associated with reduced genomic integrity by Tahamtan, Sahar, Tavalaee, Marziyeh, Izadi, Tayebeh, Barikrow, Nooshin, Zakeri, Zahra, Lockshin, Richard A., Abbasi, Homayoun, Nasr- Esfahani, Mohammad Hosseini

“…Varicocele, defined as enlarged varicose veins in the scrotum, is the most common identifiable cause of male infertility. There are significant correlations…”
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Metabolomics approach reveals urine biomarkers and pathways associated with the pathogenesis of lupus nephritis by Kalantari, Shiva, Chashmniam, Saeed, Nafar, Mohsen, Zakeri, Zahra, Parvin, Mahmoud

“…lupus nephritis (LN) is a severe form of systemic lupus erythematosus (SLE) with renal complications. Current diagnosis is based on invasive renal biopsy and…”
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Design, synthesis, α-glucosidase inhibition and hypoglycemic activity of 3-aceto(benzo)hydrazide-1,2,4-triazines as potential anti-diabetic agents by Valipour, Mehdi, Zakeri Khatir, Zahra, Kiadaliry, Kaveh, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Sayyad, Mohammad Shokati, Seyedabadi, Mohammad, Ghasemian, Majid, Hashemi, Seyedeh Mahdieh, Irannejad, Hamid

“…Type 2 diabetes is a common condition that causes the level of glucose in the blood to become too high and α-glucosidase inhibitors are therapeutic agents in…”
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Caspase-independent cell death? by Lockshin, Richard A, Zakeri, Zahra

“…Many cells die with apoptotic morphology and with documented activation of an effector caspase, but there are also many exceptions. Cells frequently display…”
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New trends in cell death: overview of the International Society of Cell Death (ICDS) annual meeting in Johannesburg South Africa (May 19-22, 2023) by Cronjé, Marianne J, Gadiyar, Varsha, Chipuk, Jerry Edward, Bagci-Onder, Tugba, Krysko, Dmitri, Birge, Raymond B, Lockshin, Richard A, Zakeri, Zahra

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Higher sensitivity of female cells to ethanol: methylation of DNA lowers Cyp2e1, generating more ROS by Penaloza, Carlos G, Cruz, Mayra, Germain, Gabrielle, Jabeen, Sidra, Javdan, Mohammad, Lockshin, Richard A, Zakeri, Zahra

“…Cells taken from mouse embryos before sex differentiation respond to insults according to their chromosomal sex, a difference traceable to differential…”
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mTOR/p70S6K signaling distinguishes routine, maintenance-level autophagy from autophagic cell death during influenza A infection by Datan, Emmanuel, Shirazian, Alireza, Benjamin, Shawna, Matassov, Demetrius, Tinari, Antonella, Malorni, Walter, Lockshin, Richard A, Garcia-Sastre, Adolfo, Zakeri, Zahra

“…Abstract Autophagy, a stress response activated in influenza A virus infection helps the cell avoid apoptosis. However, in the absence of apoptosis infected…”
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Association between chemerin rs17173608 and vaspin rs2236242 gene polymorphisms and the metabolic syndrome, a preliminary report by Hashemi, Mohammad, Rezaei, Hamzeh, Eskandari-Nasab, Ebrahim, kaykhaei, Mahmoud Ali, Zakeri, Zahra, Taheri, Mohsen

“…Metabolic syndrome (MeS) is associated with increased risk for type 2 diabetes mellitus (T2DM) and cardiovascular disease. There is some evidence indicating…”
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Programmed cell death and apoptosis: origins of the theory by Lockshin, Richard A, Zakeri, Zahra

“…Interest in the study of apoptosis grew with the recognition that it is a highly regulated process. Such a change in attitude allowed the intellectual and…”
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Deoxyribonuclease I gene polymorphism and susceptibility to systemic lupus erythematosus by Mohammadoo-Khorasani, Milad, Musavi, Mahsa, Mousavi, Mahdieh, Moossavi, Maryam, Khoddamian, Maryam, Sandoughi, Mahnaz, Zakeri, Zahra

“…The DNASE1 gene is regarded as one of the susceptible genes for systemic lupus erythematosus (SLE). Recent studies have detected the presence of a variable…”
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Association of FAS and FAS Ligand Genes Polymorphism and Risk of Systemic Lupus Erythematosus by Zakeri, Zahra, Sandoughi, Mahnaz, Farajian-Mashhadi, Farzaneh, Salimi, Saeedeh, Moudi, Bita

“…FAS/FASL pathway plays a critical role in maintaining peripheral immune tolerance; therefore, the apoptosis genes, Fas and Fas ligand (FasL), could be suitable…”
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