Search Results - "ZAGA, Veronica"
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Prolactin modifies the in vitro LPS‐induced chemotactic capabilities in human fetal membranes at the term of gestation
Published in American journal of reproductive immunology (1989) (01-08-2021)“…Problem Immune responses of fetal membranes involve the production of chemoattractant mediators causing infiltration of maternal and fetal leukocytes,…”
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2
New Insights into the Role of Matrix Metalloproteinases in Preeclampsia
Published in International journal of molecular sciences (20-07-2017)“…Preeclampsia is a severe pregnancy complication globally, characterized by poor placentation triggering vascular dysfunction. Matrix metalloproteinases (MMPs)…”
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3
Matrix Metalloproteinase-3 (MMP-3) Is an Endogenous Activator of the MMP-9 Secreted by Placental Leukocytes: Implication in Human Labor
Published in PloS one (29-12-2015)“…The activity of matrix degrading enzymes plays a leading role in the rupture of the fetal membranes under normal and pathological human labor, and matrix…”
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4
In vitro secretion and activity profiles of matrix metalloproteinases, MMP-9 and MMP-2, in human term extra-placental membranes after exposure to Escherichia coli
Published in Reproductive biology and endocrinology (25-01-2011)“…Premature rupture of fetal membranes (PROM) complicated with intrauterine infection has been associated to alterations of the extracellular matrix (ECM)…”
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5
Immunoendocrine Dysregulation during Gestational Diabetes Mellitus: The Central Role of the Placenta
Published in International journal of molecular sciences (01-08-2021)“…Gestational Diabetes Mellitus (GDM) is a transitory metabolic condition caused by dysregulation triggered by intolerance to carbohydrates, dysfunction of…”
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6
Pandemic-induced healthcare shifts: an observational analysis of maternal and neonatal outcomes in adolescent pregnancies
Published in Frontiers in medicine (15-10-2024)“…The COVID-19 pandemic caused widespread changes in healthcare delivery, particularly affecting vulnerable populations such as pregnant adolescents. These…”
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Key Clinical Factors Predicting Adipokine and Oxidative Stress Marker Concentrations among Normal, Overweight and Obese Pregnant Women Using Artificial Neural Networks
Published in International journal of molecular sciences (28-12-2017)“…Maternal obesity has been related to adverse neonatal outcomes and fetal programming. Oxidative stress and adipokines are potential biomarkers in such…”
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8
Innate Immune Cells and Toll-like Receptor-Dependent Responses at the Maternal-Fetal Interface
Published in International journal of molecular sciences (26-07-2019)“…During pregnancy, the placenta, the mother and the fetus exploit several mechanisms in order to avoid fetal rejection and to maintain an immunotolerant…”
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Interaction between Pathogenic Bacteria and Intrauterine Leukocytes Triggers Alternative Molecular Signaling Cascades Leading to Labor in Women
Published in Infection and Immunity (01-11-2010)“…Increased risk of preterm labor has been linked to cervicovaginal infection with Ureaplasma urealyticum and group B streptococci. Although various experimental…”
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Preserved ex vivo inflammatory status in decidual cells from women with preterm labor and subclinical intrauterine infection
Published in PloS one (22-08-2012)“…To compare the inflammatory response preserved ex vivo by decidual cells isolated from women who experienced preterm labor with and without subclinical…”
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Placentas associated with female neonates from pregnancies complicated by urinary tract infections have higher cAMP content and cytokines expression than males
Published in American journal of reproductive immunology (1989) (01-09-2021)“…Problem The cAMP pathway is involved in important biological processes including immune regulation and hormone signaling. At the feto‐maternal unit, cAMP…”
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12
Immunomodulatory role of decidual prolactin on the human fetal membranes and placenta
Published in Frontiers in immunology (09-06-2023)“…The close interaction between fetal and maternal cells during pregnancy requires multiple immune-endocrine mechanisms to provide the fetus with a tolerogenic…”
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13
Galectin-1 Elicits a Tissue-Specific Anti-Inflammatory and Anti-Degradative Effect Upon LPS-Induced Response in an Ex Vivo Model of Human Fetal Membranes Modeling an Intraamniotic Inflammation
Published in American journal of reproductive immunology (1989) (01-11-2024)“…Intrauterine infection is one of the most jeopardizing conditions associated with adverse outcomes, including preterm birth; however, multiple tolerance…”
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14
Prolactin Protects the Structural Integrity of Human Fetal Membranes by Downregulating Inflammation-induced Secretion of Matrix Metalloproteinases
Published in Immunological investigations (04-07-2022)“…Prolactin (PRL) is a pleiotropic hormone with a key role in pregnancy. In fetal membranes, PRL can regulate the secretion of pro-inflammatory factors, which…”
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A time-course regulatory and kinetic expression study of steroid metabolizing enzymes by calcitriol in primary cultured human placental cells
Published in The Journal of steroid biochemistry and molecular biology (01-03-2017)“…•Syncytiotrophoblasts shows higher expression of the steroideogenic enzymes than cytotrophoblasts.•Short time calcitriol treatment increases the CYP11A1,…”
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High Glucose Promotes Inflammation and Weakens Placental Defenses against E. coli and S. agalactiae Infection: Protective Role of Insulin and Metformin
Published in International journal of molecular sciences (09-03-2023)“…Placentas from gestational diabetes mellitus (GDM) patients undergo significant metabolic and immunologic adaptations due to hyperglycemia, which results in an…”
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Compartmentalized Innate Immune Response of Human Fetal Membranes against Escherichia coli Choriodecidual Infection
Published in International journal of molecular sciences (10-03-2022)“…An infectious process into the uterine cavity represents a major endangered condition that compromises the immune privilege of the maternal-fetal unit and…”
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18
Cadmium induces α1collagen (I) and metallothionein II gene and alters the antioxidant system in rat hepatic stellate cells
Published in Toxicology (Amsterdam) (01-01-2002)Get full text
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Regulation of CYP27B1 and CYP24A1 gene expression by recombinant pro-inflammatory cytokines in cultured human trophoblasts
Published in The Journal of steroid biochemistry and molecular biology (01-10-2014)“…•Cytokines regulate calcitriol metabolism in human placenta.•INFγ contributes to calcitriol anabolism.•TNFα favors the catabolism of calcitriol. Placenta is an…”
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Cord Serum Calcitriol Inversely Correlates with Maternal Blood Pressure in Urinary Tract Infection-Affected Pregnancies: Sex-Dependent Immune Implications
Published in Nutrients (04-09-2021)“…Urinary tract infections (UTI) during pregnancy are frequently associated with hypertensive disorders, increasing the risk of perinatal morbidity. Calcitriol,…”
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