Search Results - "ZACCHINO, Susana"

Plant phenolics and terpenoids as adjuvants of antibacterial and antifungal drugs by Zacchino, Susana A., Butassi, Estefania, Liberto, Melina Di, Raimondi, Marcela, Postigo, Agustina, Sortino, Maximiliano

“…The intensive use of antibacterial and antifungal drugs has dramatically increased the microbial resistance and has led to a higher number of…”
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Hybrid combinations containing natural products and antimicrobial drugs that interfere with bacterial and fungal biofilms by Zacchino, Susana A., Butassi, Estefanía, Cordisco, Estefanía, Svetaz, Laura A.

“…Biofilms contribute to the pathogenesis of many chronic and difficult-to eradicate infections whose treatment is complicated due to the intrinsic resistance to…”
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Celebration of the 50th anniversary of the Korean society of Pharmacognosy (KSP) by Zacchino, Prof Susana A.

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Synthesis and Antifungal in Vitro Evaluation of Pyrazolo[3,4-b]pyridines Derivatives Obtained by Aza-Diels–Alder Reaction and Microwave Irradiation by Quiroga, Jairo, Villarreal, Yazmín, Gálvez, Jaime, Ortíz, Alejandro, Insuasty, Braulio, Abonia, Rodrigo, Raimondi, Marcela, Zacchino, Susana

“…A series of pyrazolo[3,4-b]pyridines were prepared by a microwave-assisted aza-Diels–Alder reaction between pyrazolylformimidamides 1 and β-nitrostyrenes 2 in…”
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Eco-friendly synthesis and antifungal evaluation of N-substituted benzimidazoles by Vargas-Oviedo, Diana, Butassi, Estefanía, Zacchino, Susana, Portilla, Jaime

“…A convenient synthesis of N -phenacylbenzimidazoles in high yields (90–95%) by the N -alkylation reaction of 1 H -benzimidazole with phenacyl bromides is…”
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Synthesis, Structural Characterization, and In Vitro and In Silico Antifungal Evaluation of Azo-Azomethine Pyrazoles (PhN2(PhOH)CHN(C3N2(CH3)3)PhR, R = H or NO2) by Fernandez, Dorancelly, Restrepo-Acevedo, Andrés, Rocha-Roa, Cristian, Le Lagadec, Ronan, Abonia, Rodrigo, Zacchino, Susana A., Gómez Castaño, Jovanny A., Cuenú-Cabezas, Fernando

“…The azo-azomethine imines, R1-N=N-R2-CH=N-R3, are a class of active pharmacological ligands that have been prominent antifungal, antibacterial, and antitumor…”
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Microwave-Assisted Synthesis of Novel Pyrazolo[3,4-g][1,8]naphthyridin-5-amine with Potential Antifungal and Antitumor Activity by Acosta, Paola, Butassi, Estefanía, Insuasty, Braulio, Ortiz, Alejandro, Abonia, Rodrigo, Zacchino, Susana A, Quiroga, Jairo

“…The microwave assisted reaction between heterocyclic o-aminonitriles 1 and cyclic ketones 2 catalyzed by zinc chloride led to new series of pyrazolo[3,4-b]…”
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Prenylated Flavonoids with Potential Antimicrobial Activity: Synthesis, Biological Activity, and In Silico Study by Osorio, Mauricio, Carvajal, Marcela, Vergara, Alejandra, Butassi, Estefania, Zacchino, Susana, Mascayano, Carolina, Montoya, Margarita, Mejías, Sophia, Martín, Marcelo Cortez-San, Vásquez-Martínez, Yesseny

“…Prenylated flavonoids are an important class of naturally occurring flavonoids with important biological activity, but their low abundance in nature limits…”
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Synthesis and Characterization of New Bases Derived from Nitrophenylpyrazoles, Coordination to Palladium and Antifungal Activity and Catalytic Activity in Mizoroki–Heck Reactions by Jennifer Londoño-Salazar, Andrés Restrepo-Acevedo, John Eduard Torres, Rodrigo Abonia, Laura Svetaz, Susana A. Zacchino, Ronan Le Lagadec, Fernando Cuenú-Cabezas

“…In this study, we report the synthesis of eight Schiff bases (3–10) type N-heterocycle (N-het) using conventional refluxing conditions as well as different…”
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Fungal Biofilms as a Valuable Target for the Discovery of Natural Products That Cope with the Resistance of Medically Important Fungi—Latest Findings by Butassi, Estefanía, Svetaz, Laura, Carpinella, María Cecilia, Efferth, Thomas, Zacchino, Susana

“…The development of new antifungal agents that target biofilms is an urgent need. Natural products, mainly from the plant kingdom, represent an invaluable…”
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The antifungal activity and mechanisms of action of quantified extracts from berries, leaves and roots of Phytolacca tetramera by Butassi, Estefanía, Svetaz, Laura A., Zhou, Shuaizhen, Wolfender, Jean-Luc, Cortés, Juan C.G., Ribas, Juan C., Díaz, Caridad, Palacio, José Pérez-del, Vicente, Francisca, Zacchino, Susana A.

“…Phytolacca tetramera is an endemic plant from Argentina that is currently at serious risk because its environment is subjected to a high anthropic impact. A…”
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Synthesis, antiproliferative and antifungal activities of 1,2,3-triazole-substituted carnosic Acid and carnosol derivatives by Pertino, Mariano Walter, Theoduloz, Cristina, Butassi, Estefania, Zacchino, Susana, Schmeda-Hirschmann, Guillermo

“…Abietane diterpenes exhibit an array of interesting biological activities, which have generated significant interest among the pharmacological community…”
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Value of the ethnomedical information for the discovery of plants with antifungal properties. A survey among seven Latin American countries by Svetaz, Laura, Zuljan, Federico, Derita, Marcos, Petenatti, Elisa, Tamayo, Giselle, Cáceres, Armando, Cechinel Filho, Valdir, Giménez, Alberto, Pinzón, Roberto, Zacchino, Susana A., Gupta, Mahabir

“…From the evaluation of 327 plant species from seven Latin American countries, a significantly higher probability of detecting plants with antifungal activity…”
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Antimicrobial, Anti-Inflammatory and Antioxidant Activities of Polyoxygenated Chalcones by Vásquez-Martínez, Yesseny, Osorio, Mauricio, San Martín, Diego, Carvajal, Marcela, Vergara, Alejandra, Sanchez, Elizabeth, Raimondi, Marcela, Zacchino, Susana, Mascayano, Carolina, Torrent, Claudia, Cabezas, Francisco, Mejias, Sophia, Montoya, Margarita, Cortez-San Martín, Marcelo

“…It was synthesized nine polyoxygenated chalcones with a potential and safe use as antioxidant, antimicrobial and anti-inflammatory therapies. Chalcones…”
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Structural requirements for the antifungal activities of natural drimane sesquiterpenes and analogues, supported by conformational and electronic studies by Derita, Marcos, Montenegro, Iván, Garibotto, Francisco, Enriz, Ricardo D, Fritis, Mauricio Cuellar, Zacchino, Susana A

“…Seventeen drimanes including polygodial (1), isopolygodial (2), drimenol (3) and confertifolin (4) obtained from natural sources and the semi-synthetic…”
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Approaches to the mechanism of antifungal activity of Zuccagnia punctata-Larrea nitida bi-herbal combination by Butassi, Estefanía, Svetaz, Laura A., Sortino, Maximiliano A., Quiroga, Ariel D., Carvalho, Vanessa S.D., Cortés, Juan C.G., Ribas, Juan C., Zacchino, Susana A.

“…In our previous study the synergism of four combinations of Zuccagnia punctata (ZpE) and Larrea nitida (LnE) exudates with the reliable statistical-based…”
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Antifungal activity of eugenol analogues. Influence of different substituents and studies on mechanism of action by Carrasco, Héctor, Raimondi, Marcela, Svetaz, Laura, Di Liberto, Melina, Rodriguez, María V, Espinoza, Luis, Madrid, Alejandro, Zacchino, Susana

“…Twenty one phenylpropanoids (including eugenol and safrole) and synthetic analogues, thirteen of them new compounds, were evaluated for antifungal properties,…”
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Synthesis, antifungal and antitumor activity of novel (Z)-5-hetarylmethylidene-1,3-thiazol-4-ones and (z)-5-ethylidene-1,3-thiazol-4-ones by Insuasty, Alberto, Ramírez, Juan, Raimondi, Marcela, Echeverry, Carlos, Quiroga, Jairo, Abonia, Rodrigo, Nogueras, Manuel, Cobo, Justo, Rodríguez, María Victoria, Zacchino, Susana A, Insuasty, Braulio

“…New hetaryl- and alkylidenerhodanine derivatives 3a-d, 3e, and 4a-d were prepared from heterocyclic aldehydes 1a-d or acetaldehyde 1e. The treatment of several…”
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Hybrid Molecules Containing a 7-Chloro-4-aminoquinoline Nucleus and a Substituted 2-Pyrazoline with Antiproliferative and Antifungal Activity by Montoya, Alba, Quiroga, Jairo, Abonia, Rodrigo, Derita, Marcos, Sortino, Maximiliano, Ornelas, Alfredo, Zacchino, Susana, Insuasty, Braulio

“…Twenty-four new hybrid analogues (15-38) containing 7-chloro-4-aminoquinoline and 2-pyrazoline N-heterocyclic fragments were synthesized. Twelve of the new…”
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Synthesis and DFT Calculations of Novel Vanillin-Chalcones and Their 3-Aryl-5-(4-(2-(dimethylamino)-ethoxy)-3-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbaldehyde Derivatives as Antifungal Agents by Illicachi, Luis Alberto, Montalvo-Acosta, Joel José, Insuasty, Alberto, Quiroga, Jairo, Abonia, Rodrigo, Sortino, Maximiliano, Zacchino, Susana, Insuasty, Braulio

“…Novel ( )-1-(aryl)-3-(4-(2-(dimethylamino)ethoxy)-3-methoxyphenyl) prop-2-en-1-ones were synthesized by a Claisen-Schmidt reaction of…”
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