Search Results - "Žusinaite, Eva"

Phosphorylation Sites in the Hypervariable Domain in Chikungunya Virus nsP3 Are Crucial for Viral Replication by Teppor, Mona, Žusinaite, Eva, Merits, Andres

“…Chikungunya virus (CHIKV, family ) is a mosquito-transmitted alphavirus. The positive-sense RNA genome of CHIKV encodes four nonstructural proteins (nsP1 to…”
Get full text

Reverse genetic system, genetically stable reporter viruses and packaged subgenomic replicon based on a Brazilian Zika virus isolate by Mutso, Margit, Saul, Sirle, Rausalu, Kai, Susova, Olga, Žusinaite, Eva, Mahalingam, Suresh, Merits, Andres

“…Zika virus (ZIKV, genus Flavivirus) has emerged as a major mosquito-transmitted human pathogen, with recent outbreaks associated with an increased incidence of…”
Get full text

Semliki Forest Virus Chimeras with Functional Replicase Modules from Related Alphaviruses Survive by Adaptive Mutations in Functionally Important Hot Spots by Teppor, Mona, Žusinaite, Eva, Karo-Astover, Liis, Omler, Ailar, Rausalu, Kai, Lulla, Valeria, Lulla, Aleksei, Merits, Andres

“…Alphaviruses (family ) include both human pathogens such as chikungunya virus (CHIKV) and Sindbis virus (SINV) and model viruses such as Semliki Forest virus…”
Get full text

Novel Functions of the Alphavirus Nonstructural Protein nsP3 C-Terminal Region by VARJAK, Margus, ZUSINAITE, Eva, MERITS, Andres

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication by Scholte, Florine E M, Tas, Ali, Albulescu, Irina C, Žusinaite, Eva, Merits, Andres, Snijder, Eric J, van Hemert, Martijn J

“…Stress granules (SGs) are protein-mRNA aggregates that are formed in response to environmental stresses, resulting in translational inhibition. SGs are…”
Get full text

HIV Replication Is Increased by RNA Methylation METTL3/METTL14/WTAP Complex Activators by Selberg, Simona, Žusinaite, Eva, Herodes, Koit, Seli, Neinar, Kankuri, Esko, Merits, Andres, Karelson, Mati

“…The N6-methyladenosine (m6A) modifications in both viral and host cell RNAs play an important role in HIV-1 virus genome transcription and virus replication…”
Get full text

Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease’s active site cysteine residue by Rausalu, Kai, Utt, Age, Quirin, Tania, Varghese, Finny S., Žusinaite, Eva, Das, Pratyush Kumar, Ahola, Tero, Merits, Andres

“…Chikungunya virus (CHIKV), genus Alphavirus, family Togaviridae, has a positive-stand RNA genome approximately 12 kb in length. In infected cells, the genome…”
Get full text

Bovine colostrum-derived antibodies against SARS-CoV-2 show great potential to serve as prophylactic agents by Kangro, Kadri, Kurašin, Mihhail, Gildemann, Kiira, Sankovski, Eve, Žusinaite, Eva, Lello, Laura Sandra, Pert, Raini, Kavak, Ants, Poikalainen, Väino, Lepasalu, Lembit, Kuusk, Marilin, Pau, Robin, Piiskop, Sander, Rom, Siimu, Oltjer, Ruth, Tiirik, Kairi, Kogermann, Karin, Plaas, Mario, Tiirats, Toomas, Aasmäe, Birgit, Plaas, Mihkel, Mumm, Karl, Krinka, Dagni, Talpsep, Ene, Kadaja, Meelis, Gerhold, Joachim M, Planken, Anu, Tover, Andres, Merits, Andres, Männik, Andres, Ustav, Jr, Mart, Ustav, Mart

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to impose a serious burden on health systems globally. Despite worldwide vaccination,…”
Get full text

Antibacterial and Antiviral Effects of Ag, Cu and Zn Metals, Respective Nanoparticles and Filter Materials Thereof against Coronavirus SARS-CoV-2 and Influenza A Virus by Kubo, Anna-Liisa, Rausalu, Kai, Savest, Natalja, Žusinaite, Eva, Vasiliev, Grigory, Viirsalu, Mihkel, Plamus, Tiia, Krumme, Andres, Merits, Andres, Bondarenko, Olesja

“…Due to the high prevalence of infectious diseases and their concurrent outbreaks, there is a high interest in developing novel materials with antimicrobial…”
Get full text

1,3-Thiazolbenzamide Derivatives as Chikungunya Virus nsP2 Protease Inhibitors by Ivanova, Larisa, Rausalu, Kai, Žusinaite, Eva, Tammiku-Taul, Jaana, Merits, Andres, Karelson, Mati

“…Chikungunya fever results from an infection with Chikungunya virus (CHIKV, genus Alphavirus) that is prevalent in tropical regions and is spreading fast to…”
Get full text

Prevalence of SARS-CoV-2 IgG antibodies and their association with clinical symptoms of COVID-19 in Estonia (KoroSero-EST-1 study) by Jõgi, Piia, Soeorg, Hiie, Ingerainen, Diana, Soots, Mari, Lättekivi, Freddy, Naaber, Paul, Toompere, Karolin, Peterson, Pärt, Haljasmägi, Liis, Žusinaite, Eva, Vaas, Hannes, Pauskar, Merit, Shablinskaja, Arina, Kaarna, Katrin, Paluste, Heli, Kisand, Kai, Oona, Marje, Janno, Riina, Lutsar, Irja

“…In Estonia, during the first wave of COVID-19 total number of cases confirmed by PCR was 13.3/10,000, similar in most regions, including capital Tallinn, but…”
Get full text

Novel Analogues of the Chikungunya Virus Protease Inhibitor: Molecular Design, Synthesis, and Biological Evaluation by Ivanova, Larisa, Rausalu, Kai, Ošeka, Maksim, Kananovich, Dzmitry G, Žusinaite, Eva, Tammiku-Taul, Jaana, Lopp, Margus, Merits, Andres, Karelson, Mati

“…The Chikungunya virus (CHIKV) is an arbovirus belonging to the genus Alphavirus of the Togaviridae family. CHIKV is transmitted by the mosquitoes and causes…”
Get full text

Posaconazole inhibits dengue virus replication by targeting oxysterol-binding protein by Meutiawati, Febrina, Bezemer, Bodine, Strating, Jeroen R.P.M., Overheul, Gijs J., Žusinaite, Eva, van Kuppeveld, Frank J.M., van Cleef, Koen W.R., van Rij, Ronald P.

“…Dengue virus (DENV) is associated with an estimated 390 million infections per year, occurring across approximately 100 countries in tropical and sub-tropical…”
Get full text

Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in non-human primates by Hermet, Paule, Delache, Benoît, Herate, Cecile, Wolf, Esther, Kivi, Gaily, Juronen, Erkki, Mumm, Karl, Žusinaite, Eva, Kainov, Denis, Sankovski, Eve, Virumäe, Kai, Planken, Anu, Merits, Andres, Besaw, Jessica E, Yee, Ai Woon, Morizumi, Takefumi, Kim, Kyumhyuk, Kuo, Anling, Berriche, Asma, Dereuddre-Bosquet, Nathalie, Sconosciuti, Quentin, Naninck, Thibaut, Relouzat, Francis, Cavarelli, Mariangela, Ustav, Mart, Wilson, Derek, Ernst, Oliver P, Männik, Andres, LeGrand, Roger, Ustav, Jr, Mart

“…The COVID-19 pandemic represents a global challenge that has impacted and is expected to continue to impact the lives and health of people across the world for…”
Get full text

Basic insights into Zika virus infection of neuroglial and brain endothelial cells by Mutso, Margit, St John, James A, Ling, Zheng Lung, Burt, Felicity J, Poo, Yee Suan, Liu, Xiang, Žusinaite, Eva, Grau, Georges E, Hueston, Linda, Merits, Andres, King, Nicholas J C, Ekberg, Jenny A K, Mahalingam, Suresh

“…Zika virus (ZIKV) has recently emerged as an important human pathogen due to the strong evidence that it causes disease of the central nervous system,…”
Get full text

Reverse genetic system, genetically stable reporter viruses and packaged subgenomic replicon based on a Brazilian Zika virus isolate by Mutso, Margit, Saul, Sirle, Rausalu, Kai, Susova, Olga, Žusinaite, Eva, Mahalingam, Suresh, Merits, Andres

Get full text

RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications by Mutso, Margit, Nikonov, Andrei, Pihlak, Arno, Žusinaite, Eva, Viru, Liane, Selyutina, Anastasia, Reintamm, Tõnu, Kelve, Merike, Saarma, Mart, Karelson, Mati, Merits, Andres

“…The inhibitory potency of an antisense oligonucleotide depends critically on its design and the accessibility of its target site. Here, we used an RNA…”
Get full text

Protective antibodies and T cell responses to Omicron variant after the booster dose of BNT162b2 vaccine by Naaber, Paul, Tserel, Liina, Kangro, Kadri, Punapart, Marite, Sepp, Epp, Jürjenson, Virge, Kärner, Jaanika, Haljasmägi, Liis, Haljasorg, Uku, Kuusk, Marilin, Sankovski, Eve, Planken, Anu, Ustav, Mart, Žusinaite, Eva, Gerhold, Joachim M., Kisand, Kai, Peterson, Pärt

“…The high number of mutations in the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes its immune escape. We report a…”
Get full text

Mutations at the palmitoylation site of non-structural protein nsP1 of Semliki Forest virus attenuate virus replication and cause accumulation of compensatory mutations by Zusinaite, Eva, Tints, Kairit, Kiiver, Kaja, Spuul, Pirjo, Karo-Astover, Liis, Merits, Andres, Sarand, Inga

“…1 Institute of Molecular and Cell Biology, University of Tartu, Nooruse 1, 50411 Tartu, Estonia 2 Estonian Biocentre, Riia Street 23, 51010 Tartu, Estonia 3…”
Get full text

The infection of mammalian and insect cells with SFV bearing nsP1 palmitoylation mutations by Karo-Astover, Liis, Šarova, Oksana, Merits, Andres, Žusinaite, Eva

“…Semliki Forest virus (SFV), an alphavirus, replicates in vertebrate host and mosquito vector cells. The virus-specific part of the replicase complex…”
Get full text