Search Results - "Ząbczyńska, Marta"
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Raman-based spectrophenotyping of the most important cells of the immune system
Published in Journal of advanced research (01-11-2022)“…[Display omitted] •Raman spectroscopy was able to differentiate between white blood cells.•Bands of carotenoids and nucleic acids are specific Raman markers…”
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Decreased Immunoglobulin G Core Fucosylation, A Player in Antibody-dependent Cell-mediated Cytotoxicity, is Associated with Autoimmune Thyroid Diseases
Published in Molecular & cellular proteomics (01-05-2020)“…The glycosylation profile for IgG and PBMC and their associations with AITD and one of its biomarkers, TPOAb, have been determined in three independent…”
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Glycosylation in the Thyroid Gland: Vital Aspects of Glycoprotein Function in Thyrocyte Physiology and Thyroid Disorders
Published in International journal of molecular sciences (17-09-2018)“…The key proteins responsible for hormone synthesis in the thyroid are glycosylated. Oligosaccharides strongly affect the function of glycosylated proteins…”
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The Contribution of IgG Glycosylation to Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) and Complement-Dependent Cytotoxicity (CDC) in Hashimoto's Thyroiditis: An in Vitro Model of Thyroid Autoimmunity
Published in Biomolecules (Basel, Switzerland) (22-01-2020)“…Antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) are involved in destruction of thyroid tissue in Hashimoto's…”
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Altered N-glycan profile of IgG-depleted serum proteins in Hashimoto's thyroiditis
Published in Biochimica et biophysica acta. General subjects (01-03-2020)“…Hashimoto's thyroiditis (HT) is an autoimmune disease characterized by chronic inflammation of thyroid gland. Although HT is the most common cause of…”
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Towards Raman-Based Screening of Acute Lymphoblastic Leukemia-Type B (B-ALL) Subtypes
Published in Cancers (31-10-2021)“…Acute lymphoblastic leukemia (ALL) is the most common type of malignant neoplasms in the pediatric population. B-cell precursor ALLs (BCP-ALLs) are derived…”
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IgG glycosylation in autoimmune diseases
Published in Postȩpy higieny i medycyny doświadczalnej (12-11-2018)“…Immunoglobulin G (IgG) is the most abundant glycoprotein in human serum. All IgG subclasses have a single-conserved N-linked glycosylation site at Asn297 of…”
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The role of protein glycosylation in immune system
Published in Postępy biochemii (2015)“…Glycosylation is one of the most frequent post-translational modifications of proteins. The majority of cell surface and secreted proteins involved in immune…”
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Immunosuppressive Drugs Affect High-Mannose/Hybrid N-Glycans on Human Allostimulated Leukocytes
Published in Analytical cellular pathology (Amsterdam) (01-01-2015)“…N-glycosylation plays an important role in the majority of physiological and pathological processes occurring in the immune system. Alteration of the type and…”
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β1,6-branched complex-type N-glycans affect FAK signaling in metastatic melanoma cells
Published in Cancer investigation (02-01-2016)“…Integrin-dependent binding of the cell to extracellular matrix (ECM) is a key activator of the focal adhesion kinase (FAK) signaling pathway. N-glycosylation…”
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Decreased Immunoglobulin G Core Fucosylation, A Player in Antibody-dependent Cell-mediated Cytotoxicity, is Associated with Autoimmune Thyroid Diseases
Published in Molecular & cellular proteomics (01-05-2020)“…Autoimmune thyroid diseases (AITD) are the most common group of autoimmune diseases, associated with lymphocyte infiltration and the production of thyroid…”
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Raman spectroscopy can recognize the KMT2A rearrangement as a distinct subtype of leukemia
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-06-2024)“…[Display omitted] •Raman spectroscopy distinguishes normal and leukemic cells.•KMT2A-r BCP-ALL blasts can be identified in a label-free way.•The 1040/1008 cm−1…”
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