Search Results - "Zühlke, Liesl J."

Rheumatic Heart Disease Worldwide: JACC Scientific Expert Panel by Watkins, David A, Beaton, Andrea Z, Carapetis, Jonathan R, Karthikeyan, Ganesan, Mayosi, Bongani M, Wyber, Rosemary, Yacoub, Magdi H, Zühlke, Liesl J

“…Rheumatic heart disease (RHD) is a preventable heart condition that remains endemic among vulnerable groups in many countries. After a period of relative…”
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Estimates of the Global Burden of Rheumatic Heart Disease by Zühlke, Liesl J, Steer, Andrew C

“…Abstract In this review, we make the case that currently available figures used to define the global burden of acute rheumatic fever and rheumatic heart…”
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Presence of Group A streptococcus frequently assayed virulence genes in invasive disease: a systematic review and meta-analysis by Rampersadh, Kimona, Salie, M Taariq, Engel, Kelin C, Moodley, Clinton, Zühlke, Liesl J, Engel, Mark E

“…It is currently unclear what the role of Group A streptococcus (GAS) virulence factors (VFs) is in contributing to the invasive potential of GAS. This work…”
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Pediatric systemic lupus erythematosus patients in South Africa have high prevalence and severity of cardiac and vascular manifestations by Harrison, Michael J, Zühlke, Liesl J, Lewandowski, Laura B, Scott, Christiaan

“…Pediatric onset of systemic lupus erythematosus (SLE) is associated with major organ involvement, and African patients tend to develop more aggressive disease…”
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Group A Streptococcus, Acute Rheumatic Fever and Rheumatic Heart Disease: Epidemiology and Clinical Considerations by Zühlke, Liesl J., Beaton, Andrea, Engel, Mark E., Hugo-Hamman, Christopher T., Karthikeyan, Ganesan, Katzenellenbogen, Judith M., Ntusi, Ntobeko, Ralph, Anna P., Saxena, Anita, Smeesters, Pierre R., Watkins, David, Zilla, Peter, Carapetis, Jonathan

“…Opinion statement Early recognition of group A streptococcal pharyngitis and appropriate management with benzathine penicillin using local clinical prediction…”
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Outcomes Following Neonatal Cardiac Surgery in Cape Town, South Africa by du Toit, Derrik, Swanson, Lenise C., Salie, Shamiel, Perkins, Susan, Basera, Wisdom, Lawrenson, John B., Aldersley, Thomas, Brooks, Andre, Zühlke, Liesl J.

“…Background Neonatal Cardiac Surgery has developed significantly since its advent, with improved outcomes, survival, and physiological repair. Limited programs…”
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Sex differences in the etiology and burden of heart failure across country income level: analysis of 204 countries and territories 1990–2019 by Wei, Sunny, Miranda, J Jamie, Mamas, Mamas A, Zühlke, Liesl J, Kontopantelis, Evan, Thabane, Lehana, Van Spall, Harriette G C

“…Abstract Background Heart failure (HF) is a global epidemic. Objective To assess global sex differences in HF epidemiology across country income levels…”
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Epidemiology of pharyngitis as reported by Zambian school children and their families: implications for demand-side interventions to prevent rheumatic heart disease by Musuku, John, Lungu, Joyce C, Machila, Elizabeth, Jones, Catherine, Colin, Laurence, Schwaninger, Sherri, Musonda, Patrick, Tadmor, Brigitta, Spector, Jonathan M, Engel, Mark E, Zühlke, Liesl J

“…Prompt and appropriate treatment of streptococcal pharyngitis decreases the risk of acute rheumatic fever and rheumatic heart disease (RHD). Understanding…”
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Prevalence of rheumatic heart disease in Zambian school children by Musuku, John, Engel, Mark E, Musonda, Patrick, Lungu, Joyce Chipili, Machila, Elizabeth, Schwaninger, Sherri, Mtaja, Agnes, Mulendele, Evans, Kavindele, Dorothy, Spector, Jonathan, Tadmor, Brigitta, Gutierrez, Marcelo M, Van Dam, Joris, Colin, Laurence, Long, Aidan, Fishman, Mark C, Mayosi, Bongani M, Zühlke, Liesl J

“…The large global burden of rheumatic heart disease (RHD) has come to light in recent years following robust epidemiologic studies. As an operational research…”
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The RHD Action Small Grants Programme: Small Investment, Big Return by Abdullahi, Leila, Albertus, Cleo, Perkins, Susan, Ralston, Kate, White, Alastair, Mwangi, Jeremiah, Zühlke, Liesl J

“…Rheumatic Heart Disease (RHD) remains endemic in low- and middle-income countries (LMICs) despite its virtual elimination in high-income countries. RHD Action…”
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IL27 gene expression distinguishes multisystem inflammatory syndrome in children from febrile illness in a South African cohort by Spracklen, Timothy F, Mendelsohn, Simon C, Butters, Claire, Facey-Thomas, Heidi, Stander, Raphaella, Abrahams, Debbie, Erasmus, Mzwandile, Baguma, Richard, Day, Jonathan, Scott, Christiaan, Zühlke, Liesl J, Kassiotis, George, Scriba, Thomas J, Webb, Kate

“…Multisystem inflammatory syndrome in children (MIS-C) is a severe acute inflammatory reaction to SARS-CoV-2 infection in children. There is a lack of data…”
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Mortality and Heart Transplantation After Hybrid Palliation of Hypoplastic Left Heart Syndrome: A Systematic Review and Meta-Analysis by Jacquemyn, Xander, Singh, Tajinder P., Gossett, Jeffrey G., Averin, Konstantin, Kutty, Shelby, Zühlke, Liesl J., Abdullahi, Leila H., Kulkarni, Aparna

“…Background Newborns with hypoplastic left heart syndrome (HLHS) who are considered at increased risk for death following Norwood/Sano surgery often undergo…”
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Evaluation of a focussed protocol for hand-held echocardiography and computer-assisted auscultation in detecting latent rheumatic heart disease in scholars by Zühlke, Liesl J, Engel, Mark E, Nkepu, Simpiwe, Mayosi, Bongani M

“…Introduction Echocardiography is the diagnostic test of choice for latent rheumatic heart disease. The utility of echocardiography for large-scale screening is…”
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Integrating the Prevention and Control of Rheumatic Heart Disease into Country Health Systems: A Systematic Review and Meta-Analysis by Abrams, Jessica, Watkins, David A, Abdullahi, Leila H, Zühlke, Liesl J, Engel, Mark E

“…National and international political commitments have been made recently on rheumatic heart disease (RHD), a preventable heart condition that is endemic in…”
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Serum Immune Responses to Group A Streptococcal Antigens following Pharyngeal Acquisitions among Children in Cape Town, South Africa by Salie, M Taariq, Muhamed, Babu, Engel, Kélin, Rampersadh, Kimona, Daniels, Rezeen, Mhlanti, Lwazi, Penfound, Thomas A, Sable, Craig A, Zühlke, Liesl J, Dale, James B, Engel, Mark E

“…There is limited information on the human immune response following infection with group A (Strep A). Animal studies have shown, in addition to the M protein,…”
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The Importance of Awareness and Education in Prevention and Control of RHD by Zühlke, Liesl J, Engel, Mark E

“…Abstract Acute rheumatic fever and rheumatic heart disease are diseases of poverty, low socioeconomic status, and inadequate access to health care. These…”
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Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases by Salie, M Taariq, Yang, Jing, Ramírez Medina, Carlos R, Zühlke, Liesl J, Chishala, Chishala, Ntsekhe, Mpiko, Gitura, Bernard, Ogendo, Stephen, Okello, Emmy, Lwabi, Peter, Musuku, John, Mtaja, Agnes, Hugo-Hamman, Christopher, El-Sayed, Ahmed, Damasceno, Albertino, Mocumbi, Ana, Bode-Thomas, Fidelia, Yilgwan, Christopher, Amusa, Ganiyu A, Nkereuwem, Esin, Shaboodien, Gasnat, Da Silva, Rachael, Lee, Dave Chi Hoo, Frain, Simon, Geifman, Nophar, Whetton, Anthony D, Keavney, Bernard, Engel, Mark E

“…Rheumatic heart disease (RHD) remains a major source of morbidity and mortality in developing countries. A deeper insight into the pathogenetic mechanisms…”
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Utility of Human Immune Responses to GAS Antigens as a Diagnostic Indicator for ARF: A Systematic Review by Salie, M Taariq, Rampersadh, Kimona, Muhamed, Babu, Engel, Kélin C, Zühlke, Liesl J, Dale, James B, Engel, Mark E

“…Previous studies have established that streptococcal antibody titer is correlated with a diagnosis of acute rheumatic fever (ARF). However, results vary in the…”
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Association of Novel Locus With Rheumatic Heart Disease in Black African Individuals: Findings From the RHDGen Study by Machipisa, Tafadzwa, Chong, Michael, Muhamed, Babu, Chishala, Chishala, Shaboodien, Gasnat, Pandie, Shahiemah, de Vries, Jantina, Laing, Nakita, Joachim, Alexia, Daniels, Rezeen, Ntsekhe, Mpiko, Hugo-Hamman, Christopher T, Gitura, Bernard, Ogendo, Stephen, Lwabi, Peter, Okello, Emmy, Damasceno, Albertino, Novela, Celia, Mocumbi, Ana O, Madeira, Goeffrey, Musuku, John, Mtaja, Agnes, ElSayed, Ahmed, Elhassan, Huda H M, Bode-Thomas, Fidelia, Okeahialam, Basil N, Zühlke, Liesl J, Mulder, Nicola, Ramesar, Raj, Lesosky, Maia, Parks, Tom, Cordell, Heather J, Keavney, Bernard, Engel, Mark E, Paré, Guillaume

“…Rheumatic heart disease (RHD), a sequela of rheumatic fever characterized by permanent heart valve damage, is the leading cause of cardiac surgery in Africa…”
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The Namibian Children's Heart Project: a South-South partnership to provide cardiac care by Shidhika, Fenny F, Hugo-Hamman, Christopher T, Lawrenson, John B, Du Toit, Henning J, Vosloo, Susan M, Brooks, Andre, Pribut, Harold S, Perkins, Susan R, Zühlke, Liesl J

“…IntroductionCongenital and acquired heart diseases are highly prevalent in developing countries despite limited specialised care. Namibia established a…”
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