Search Results - "Zögg, Thomas"

The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier by Ruprecht, Jonathan J., King, Martin S., Zögg, Thomas, Aleksandrova, Antoniya A., Pardon, Els, Crichton, Paul G., Steyaert, Jan, Kunji, Edmund R.S.

“…Mitochondrial ADP/ATP carriers transport ADP into the mitochondrial matrix for ATP synthesis, and ATP out to fuel the cell, by cycling between cytoplasmic-open…”
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Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM by Uchański, Tomasz, Masiulis, Simonas, Fischer, Baptiste, Kalichuk, Valentina, López-Sánchez, Uriel, Zarkadas, Eleftherios, Weckener, Miriam, Sente, Andrija, Ward, Philip, Wohlkönig, Alexandre, Zögg, Thomas, Remaut, Han, Naismith, James H., Nury, Hugues, Vranken, Wim, Aricescu, A. Radu, Pardon, Els, Steyaert, Jan

“…Nanobodies are popular and versatile tools for structural biology. They have a compact single immunoglobulin domain organization, bind target proteins with…”
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Allosteric nanobodies to study the interactions between SOS1 and RAS by Fischer, Baptiste, Uchański, Tomasz, Sheryazdanova, Aidana, Gonzalez, Simon, Volkov, Alexander N., Brosens, Elke, Zögg, Thomas, Kalichuk, Valentina, Ballet, Steven, Versées, Wim, Sablina, Anna A., Pardon, Els, Wohlkönig, Alexandre, Steyaert, Jan

“…Protein-protein interactions (PPIs) are central in cell metabolism but research tools for the structural and functional characterization of these PPIs are…”
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An improved yeast surface display platform for the screening of nanobody immune libraries by Uchański, Tomasz, Zögg, Thomas, Yin, Jie, Yuan, Daopeng, Wohlkönig, Alexandre, Fischer, Baptiste, Rosenbaum, Daniel M., Kobilka, Brian K., Pardon, Els, Steyaert, Jan

“…Fusions to the C-terminal end of the Aga2p mating adhesion of Saccharomyces cerevisiae have been used in many studies for the selection of affinity reagents by…”
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Structural Basis of the Cofactor- and Substrate-Assisted Activation of Human Coagulation Factor IXa by Zögg, Thomas, Brandstetter, Hans

“…Human coagulation factor IX serves both to maintain and to control blood coagulation. The dual function of this hemophilic factor is implemented by a tiered…”
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Structural basis of purine nucleotide inhibition of human uncoupling protein 1 by Jones, Scott A, Gogoi, Prerana, Ruprecht, Jonathan J, King, Martin S, Lee, Yang, Zögg, Thomas, Pardon, Els, Chand, Deepak, Steimle, Stefan, Copeman, Danielle M, Cotrim, Camila A, Steyaert, Jan, Crichton, Paul G, Moiseenkova-Bell, Vera, Kunji, Edmund R S

“…Mitochondrial uncoupling protein 1 (UCP1) gives brown adipose tissue of mammals its specialized ability to burn calories as heat for thermoregulation. When…”
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Maturation of coagulation factor IX during Xase formation as deduced using factor VIII‐derived peptides by Fang, Han, Zögg, Thomas, Brandstetter, Hans

“…Blood coagulation involves extrinsic and intrinsic pathways, which merge at the activation step of blood coagulation factor X to factor Xa. This step is…”
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Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis by Zögg, Thomas, Sponring, Michael, Schindler, Sabrina, Koll, Maria, Schneider, Rainer, Brandstetter, Hans, Auer, Bernhard

“…Npro is a key effector protein of pestiviruses such as bovine viral diarrhea virus and abolishes host cell antiviral defense mechanisms. Synthesized as the…”
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A biosensor-based phage display selection method for automated, high-throughput Nanobody discovery by De Keyser, Phebe, Kalichuk, Valentina, Zögg, Thomas, Wohlkönig, Alexandre, Schenck, Stephan, Brunner, Janine, Pardon, Els, Steyaert, Jan

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The structural mechanism of transport by the mitochondrial ADP/ATP carrier by Kunji, Edmund R.S., Ruprecht, Jonathan J., King, Martin S., Zögg, Thomas, Aleksandrova, Antoniya A., Pardon, Els, Crichton, Paul G., Steyaert, Jan

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The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers by Dahms, Sven O., Creemers, John W. M., Schaub, Yvonne, Bourenkov, Gleb P., Zögg, Thomas, Brandstetter, Hans, Than, Manuel E.

“…Proprotein Convertases (PCs) represent highly selective serine proteases that activate their substrates upon proteolytic cleavage. Their inhibition is a…”
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Activation mechanisms of coagulation factor IX by Zögg, Thomas, Brandstetter, Hans

“…Blood haemostasis is accomplished by a complex network of coagulatory and fibrinolytic processes. These processes have to be delicately balanced, as clinically…”
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Complex Assemblies of Factors IX and X Regulate the Initiation, Maintenance, and Shutdown of Blood Coagulation by Zögg, Thomas, Brandstetter, Hans

“…Blood hemostasis is accomplished by a complex network of (anti-)coagulatory and fibrinolytic processes. These physiological processes are implemented by the…”
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Npro autoprotease fusion technology (NAFT), a platform for industrial peptide/protein production in E. coli by Auer, Bernhard, Schneider, Rainer, Heel, Thomas, Sponring, Michael, Koll, Maria, Schindler, Sabrina, Zögg, Thomas, Brandstetter, Hans

“…The human enterobacterium Escherichia coli is still one of the most used hosts for protein/peptide production in industry because of the advantage of short…”
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