Search Results - "Zárate, Francisco"

A three-dimensional FEM–DEM technique for predicting the evolution of fracture in geomaterials and concrete by Zárate, Francisco, Cornejo, Alejandro, Oñate, Eugenio

“…This paper extends to three dimensions (3D), the computational technique developed by the authors in 2D for predicting the onset and evolution of fracture in a…”
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Exchange of functional domains between a bacterial conjugative relaxase and the integrase of the human adeno-associated virus by Agúndez, Leticia, Zárate-Pérez, Francisco, Meier, Anita F, Bardelli, Martino, Llosa, Matxalen, Escalante, Carlos R, Linden, R Michael, Henckaerts, Els

“…Endonucleases of the HUH family are specialized in processing single-stranded DNA in a variety of evolutionarily highly conserved biological processes related…”
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A simple FEM–DEM technique for fracture prediction in materials and structures by Zárate, Francisco, Oñate, Eugenio

“…This paper presents a new computational technique for predicting the onset and evolution of fracture in a continuum in a simple manner combining the finite…”
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Spontaneous pneumomediastinum in COVID-19 patients. Case series by Bolaños-Morales, Francina V, Santibáñez-Salgado, J Alfredo, Guadarrama-Pérez, Cristóbal, Herrera-Zamora, Julio de J, Armas-Zárate, Francisco J, Santillán-Doherty, Patricio J

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Combination of the finite element method and particle-based methods for predicting the failure of reinforced concrete structures under extreme water forces by Oñate, Eugenio, Cornejo, Alejandro, Zárate, Francisco, Kashiyama, Kazuo, Franci, Alessandro

“…We present a combination of the Finite Element Method (FEM), the Particle Finite Element Method (PFEM), and the Discrete Element Method (DEM) for modeling and…”
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Small angle scattering reveals the orientation of cytochrome P450 19A1 in lipoprotein nanodiscs by Hackett, John C., Krueger, Susan, Urban, Volker S., Zárate-Pérez, Francisco

“…Human aromatase (CYP19A1), the cytochrome P450 enzyme responsible for conversion of androgens to estrogens, was incorporated into lipoprotein nanodiscs (NDs)…”
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Conformational selection is present in ligand binding to cytochrome P450 19A1 lipoprotein nanodiscs by Zárate-Pérez, Francisco, Hackett, John C.

“…Cytochromes P450 (CYPs) display remarkable plasticity in their ability to bind substrates and catalyze a broad array of chemical reactions. Herein we evaluate…”
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A fully Lagrangian formulation for fluid-structure interaction problems with free-surface flows and fracturing solids by Cornejo, Alejandro, Franci, Alessandro, Zárate, Francisco, Oñate, Eugenio

“…•Fluid structure interaction.•Free surface flows and fracturing solids.•Natural disaster simulation. This paper presents a novel coupled formulation for…”
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Explicit time integration scheme with large time steps for first order transient problems using finite increment calculus by Oñate, Eugenio, de Pouplana, Ignasi, Zárate, Francisco

“…We present an explicit integration scheme for solving the transient heat conduction equation that allows larger time steps than the standard forward Euler…”
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Finite element formulation for convective–diffusive problems with sharp gradients using finite calculus by Oñate, Eugenio, Zárate, Francisco, Idelsohn, Sergio R.

“…A finite element method (FEM) for steady-state convective–diffusive problems presenting sharp gradients of the solution both in the interior of the domain and…”
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Induced Fit Describes Ligand Binding to Membrane-Associated Cytochrome P450 3A4 by Sweeney, David Tyler, Zárate-Pérez, Francisco, Stokowa-Sołtys, Kamila, Hackett, John C

“…Cytochrome P450 3A4 (CYP3A4) is the dominant P450 involved in human xenobiotic metabolism. Competition for CYP3A4 therefore underlies several adverse drug-drug…”
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The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states by Santosh, Vishaka, Musayev, Faik N, Jaiswal, Rahul, Zárate-Pérez, Francisco, Vandewinkel, Bram, Dierckx, Caroline, Endicott, Molly, Sharifi, Kamyar, Dryden, Kelly, Henckaerts, Els, Escalante, Carlos R

“…Abstract The adeno-associated virus (AAV) non-structural Rep proteins catalyze all the DNA transactions required for virus viability including, DNA…”
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Fast explicit time integration schemes for parabolic problems in mechanics by Oñate, Eugenio, Zárate, Francisco, Gimenez, Juan M., Lohner, Rainald, Idelsohn, Sergio R.

“…We present a family of fast explicit time integration schemes of first, second and third order accuracy for parabolic problems in mechanics solved via standard…”
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Combination of an adaptive remeshing technique with a coupled FEM–DEM approach for analysis of crack propagation problems by Cornejo, Alejandro, Mataix, Vicente, Zárate, Francisco, Oñate, Eugenio

“…This paper presents an enhanced coupled approach between the finite element method (FEM) and the discrete element method (DEM) in which an adaptive remeshing…”
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Development and validation of a predictive model for choledocholithiasis by Huerta‐Reyna, Raúl, Guevara‐Torres, Lorenzo, Martínez‐Jiménez, Mario Aurelio, Armas‐Zarate, Francisco, Aguilar‐García, Jorge, Waldo‐Hernández, Luis Ivan, Martínez‐Martínez, Marco Ulises

“…Background Gallstone‐related conditions affect a significant portion of the population, with varying prevalence among different ethnic groups. Complications…”
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Identification of a Functionally Relevant Adeno-Associated Virus Rep68 Oligomeric Interface by Bardelli, Martino, Zárate-Pérez, Francisco, Agúndez, Leticia, Linden, R Michael, Escalante, Carlos R, Henckaerts, Els

“…The life cycle of the human parvovirus adeno-associated virus (AAV) is orchestrated by four Rep proteins. The large Rep proteins, Rep78 and Rep68, are…”
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A coupled fluid FEM-DEM technique for predicting blasting operations in tunnels by Zárate, Francisco, Gonzalez, José M., Miquel, Juan, Löhner, Rainald, Oñate, Eugenio

“…We present recent developments in the coupling of the finite element method (FEM) and the discrete element method (DEM) for the analysis of rock blasting…”
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Pulse fracture simulation in shale rock reservoirs: DEM and FEM–DEM approaches by González, José Manuel, Zárate, Francisco, Oñate, Eugenio

“…In this paper we analyze the capabilities of two numerical techniques based on DEM and FEM–DEM approaches for the simulation of fracture in shale rock caused…”
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A local constitutive model for the discrete element method. Application to geomaterials and concrete by Oñate, Eugenio, Zárate, Francisco, Miquel, Juan, Santasusana, Miquel, Celigueta, Miguel Angel, Arrufat, Ferran, Gandikota, Raju, Valiullin, Khaydar, Ring, Lev

“…This paper presents a local constitutive model for modelling the linear and non linear behavior of soft and hard cohesive materials with the discrete element…”
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Extended rotation-free plate and beam elements with shear deformation effects by ONATE, Eugenio, ZARATE, Francisco

“…This paper describes a methodology for extending rotation‐free plate and beam elements to accounting for transverse shear deformation effects. The ingredients…”
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