Search Results - "Zámbó, Boglárka"

AAV‐delivered diacylglycerol kinase DGKk achieves long‐term rescue of fragile X syndrome mouse model by Habbas, Karima, Cakil, Oktay, Zámbó, Boglárka, Tabet, Ricardos, Riet, Fabrice, Dembele, Doulaye, Mandel, Jean‐Louis, Hocquemiller, Michaël, Laufer, Ralph, Piguet, Françoise, Moine, Hervé

“…Fragile X syndrome (FXS) is the most frequent form of familial intellectual disability. FXS results from the lack of the RNA‐binding protein FMRP and is…”
Get full text

Clinically relevant mutations in the ABCG2 transporter uncovered by genetic analysis linked to erythrocyte membrane protein expression by Zámbó, Boglárka, Bartos, Zsuzsa, Mózner, Orsolya, Szabó, Edit, Várady, György, Poór, Gyula, Pálinkás, Márton, Andrikovics, Hajnalka, Hegedűs, Tamás, Homolya, László, Sarkadi, Balázs

“…The ABCG2 membrane protein is a key xeno- and endobiotic transporter, modulating the absorption and metabolism of pharmacological agents and causing multidrug…”
Get full text

Expression, Function and Trafficking of the Human ABCG2 Multidrug Transporter Containing Mutations in an Unstructured Cytoplasmic Loop by Mózner, Orsolya, Zámbó, Boglárka, Bartos, Zsuzsa, Gergely, Anna, Szabó, Kata Sára, Jezsó, Bálint, Telbisz, Ágnes, Várady, György, Homolya, László, Hegedűs, Tamás, Sarkadi, Balázs

“…The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics, contributes to cancer drug resistance and…”
Get full text

Alterations of membrane protein expression in red blood cells of Alzheimer's disease patients by Várady, György, Szabó, Edit, Fehér, Ágnes, Németh, Adrienn, Zámbó, Boglárka, Pákáski, Magdolna, Janka, Zoltán, Sarkadi, Balázs

“…Abstract Preventive measures, prognosis, or selected therapy in multifactorial maladies, including Alzheimer's disease (AD), require the application of a wide…”
Get full text

Precisely Targeted Reporters Reveal ABCG2 Regulation in Live Lung Cancer Cells by Kovacsics, Daniella, Brózik, Anna, Tihanyi, Borbála, Matula, Zsolt, Borsy, Adrienn, Mészáros, Nikolett, Szabó, Edit, Németh, Eszter, Fóthi, Ábel, Zámbó, Boglárka, Szüts, Dávid, Várady, György, Orbán, Tamás I., Apáti, Ágota, Sarkadi, Balázs

“…Abstract only Expression of the ABCG2 multidrug transporter is a marker of cancer stem cells and an indicator of poor disease outcome. Understanding the effect…”
Get full text

Cellular expression and function of naturally occurring variants of the human ABCG2 multidrug transporter by Zámbó, Boglárka, Mózner, Orsolya, Bartos, Zsuzsa, Török, György, Várady, György, Telbisz, Ágnes, Homolya, László, Orbán, Tamás I., Sarkadi, Balázs

“…The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics; thus the relatively frequent polymorphic…”
Get full text

Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy by Zambo, Boglarka, Edelweiss, Evelina, Morlet, Bastien, Negroni, Luc, Pajkos, Matyas, Dosztanyi, Zsuzsanna, Ostergaard, Soren, Trave, Gilles, Laporte, Jocelyn, Gogl, Gergo

“…Truncation of the protein-protein interaction SH3 domain of the membrane remodeling Bridging Integrator 1 (BIN1, Amphiphysin 2) protein leads to centronuclear…”
Get full text

Modulation of the Human Erythroid Plasma Membrane Calcium Pump (PMCA4b) Expression by Polymorphic Genetic Variants by Mózner, Orsolya, Zámbó, Boglárka, Sarkadi, Balázs

“…In the human ATP2B4 gene, coding for the plasma membrane calcium pump PMCA4b, a minor haplotype results in the decreased expression of this membrane protein in…”
Get full text

Quantitative fragmentomics allow affinity mapping of interactomes by Gogl, Gergo, Zambo, Boglarka, Kostmann, Camille, Cousido-Siah, Alexandra, Morlet, Bastien, Durbesson, Fabien, Negroni, Luc, Eberling, Pascal, Jané, Pau, Nominé, Yves, Zeke, Andras, Østergaard, Søren, Monsellier, Élodie, Vincentelli, Renaud, Travé, Gilles

“…Human protein networks have been widely explored but most binding affinities remain unknown, hindering quantitative interactome-function studies. Yet…”
Get full text

Genetic polymorphisms and decreased protein expression of ABCG2 urate transporters are associated with susceptibility to gout, disease severity and renal-overload hyperuricemia by Pálinkás, Márton, Szabó, Edit, Kulin, Anna, Mózner, Orsolya, Rásonyi, Rita, Juhász, Péter, Nagy, Krisztina, Várady, György, Vörös, Dóra, Zámbó, Boglárka, Sarkadi, Balázs, Poór, Gyula

“…Gout is a common crystal induced disease of high personal and social burden, characterised by severe arthritis and comorbidity if untreated. Impaired function…”
Get full text

Author Correction: Quantitative fragmentomics allow affinity mapping of interactomes by Gogl, Gergo, Zambo, Boglarka, Kostmann, Camille, Cousido-Siah, Alexandra, Morlet, Bastien, Durbesson, Fabien, Negroni, Luc, Eberling, Pascal, Jané, Pau, Nominé, Yves, Zeke, Andras, Østergaard, Søren, Monsellier, Élodie, Vincentelli, Renaud, Travé, Gilles

Get full text

Precision-engineered reporter cell lines reveal ABCG2 regulation in live lung cancer cells by Kovacsics, Daniella, Brózik, Anna, Tihanyi, Borbála, Matula, Zsolt, Borsy, Adrienn, Mészáros, Nikolett, Szabó, Edit, Németh, Eszter, Fóthi, Ábel, Zámbó, Boglárka, Szüts, Dávid, Várady, György, Orbán, Tamás I., Apáti, Ágota, Sarkadi, Balázs

“…[Display omitted] Expression of the ABCG2 multidrug transporter is a marker of cancer stem cells and a predictor of recurrent malignant disease. Understanding…”
Get full text

Decreased calcium pump expression in human erythrocytes is connected to a minor haplotype in the ATP2B4 gene by Zámbó, Boglárka, Várady, György, Padányi, Rita, Szabó, Edit, Németh, Adrienn, Langó, Tamás, Enyedi, Ágnes, Sarkadi, Balázs

“…Graphical abstract…”
Get full text

Cellular Processing of the ABCG2 Transporter-Potential Effects on Gout and Drug Metabolism by Mózner, Orsolya, Bartos, Zsuzsa, Zámbó, Boglárka, Homolya, László, Hegedűs, Tamás, Sarkadi, Balázs

“…The human ABCG2 is an important plasma membrane multidrug transporter, involved in uric acid secretion, modulation of absorption of drugs, and in drug…”
Get full text

Molecules interact. But how strong and how much? by Weimer, Kathleen, Zambo, Boglarka, Gogl, Gergo

“…Interactomics aims to characterize all interactions formed between molecules that comprise our body. Although it emerged from quantitative biophysics, it has…”
Get full text

Comparative analysis of PDZ‐binding motifs in the diacylglycerol kinase family by Zambo, Boglarka, Gogl, Gergo, Morlet, Bastien, Eberling, Pascal, Negroni, Luc, Moine, Hervé, Travé, Gilles

“…Diacylglycerol kinases (DGKs) control local and temporal amounts of diacylglycerol (DAG) and phosphatidic acid (PA) by converting DAG to PA through…”
Get full text

Characterization of a newly identified polymorphic variant (M71V) of ABCG2 multidrug transporter by Homolya, Laszlo, Bartos, Zsuzsa, Zambo, Boglarka, Mozner, Orsolya, Sarkadi, Balazs

“…The ABCG2 is a membrane transporter protein, which expels endo‐ and xenobiotics from the cells. Since its overexpression in tumor cells can confer resistance…”
Get full text

Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy by Zambo, Boglarka, Edelweiss, Evelina, Morlet, Bastien, Negroni, Luc, Pajkos, Matyas, Dosztanyi, Zsuzsanna, Ostergaard, Soren, Trave, Gilles, Laporte, Jocelyn, Gogl, Gergo

“…Truncation of the protein-protein interaction SH3 domain of the membrane remodeling Bridging Integrator 1 (BIN1, Amphiphysin 2) protein leads to centronuclear…”
Get full text

Native holdup (nHU) to measure binding affinities from cell extracts by Zambo, Boglarka, Morlet, Bastien, Negroni, Luc, Trave, Gilles, Gogl, Gergo

“…Characterizing macromolecular interactions is essential for understanding cellular processes, yet most methods currently used to detect protein interactions…”
Get full text

Quantitative fragmentomics allow affinity mapping of interactomes by Gogl, Gergo, Zambo, Boglarka, Kostmann, Camille, Cousido-Siah, Alexandra, Morlet, Bastien, Durbesson, Fabien, Negroni, Luc, Eberling, Pascal, Jané, Pau, Nominé, Yves, Zeke, Andras, Østergaard, Søren, Monsellier, Élodie, Vincentelli, Renaud, Travé, Gilles

“…Abstract Human protein networks have been widely explored but most binding affinities remain unknown, hindering quantitative interactome-function studies. Yet…”
Get full text