Search Results - "ZÚÑIGA, TIFFANY M"

Parotid glands have a dysregulated immune response following radiation therapy by Gunning, Jordan A, Gilman, Kristy E, Zúñiga, Tiffany M, Simpson, Richard J, Limesand, Kirsten H

“…Head and neck cancer treatment often consists of surgical resection of the tumor followed by ionizing radiation (IR), which can damage surrounding tissues and…”
Get full text

Granzyme F: Exhaustion Marker and Modulator of Chimeric Antigen Receptor T Cell-Mediated Cytotoxicity by Hay, Zachary L Z, Kim, Dale D, Cimons, Jennifer M, Knapp, Jennifer R, Kohler, M Eric, Quansah, Mary, Zúñiga, Tiffany M, Camp, Faye A, Fujita, Mayumi, Wang, Xiao-Jing, O'Connor, Brian P, Slansky, Jill E

“…Granzymes are a family of proteases used by CD8 T cells to mediate cytotoxicity and other less-defined activities. The substrate and mechanism of action of…”
Get full text

Maximal Exercise Alters the Inflammatory Phenotype and Response of Mononuclear Cells by SLUSHER, AARON L, ZÚÑIGA, TIFFANY M, ACEVEDO, EDMUND O

“…PURPOSEMonocytes express the CD14 receptor that facilitates lipopolysaccharide (LPS) ligation to toll-like receptor 4 (TLR4) to elicit production of…”
Get full text

Recent COVID-19 vaccination has minimal effects on the physiological responses to graded exercise in physically active healthy people by Batatinha, Helena, Baker, Forrest L, Smith, Kyle A, Zúñiga, Tiffany M, Pedlar, Charles R, Burgess, Shane C, Katsanis, Emmanuel, Simpson, Richard J

“…Athletes are advised to receive the COVID-19 vaccination to protect themselves from SARS-CoV-2 infection during major competitions. Despite this, many athletes…”
Get full text

Inflamm-Aging Is Associated with Lower Plasma PTX3 Concentrations and an Impaired Capacity of PBMCs to Express hTERT following LPS Stimulation by Slusher, Aaron L., Acevedo, Edmund O., Zúñiga, Tiffany M.

“…Age-related elevations in proinflammatory cytokines, known as inflamm-aging, are associated with shorter immune cell telomere lengths. Purpose. This study…”
Get full text

Acute exercise mobilizes NKT-like cells with a cytotoxic transcriptomic profile but does not augment the potency of cytokine-induced killer (CIK) cells by Zúñiga, Tiffany M., Baker, Forrest L., Smith, Kyle A., Batatinha, Helena, Lau, Branden, Gustafson, Michael P., Katsanis, Emmanuel, Simpson, Richard J.

“…CD3 + /CD56 + Natural killer (NK) cell-like T-cells (NKT-like cells) represent <5% of blood lymphocytes, display a cytotoxic phenotype, and can kill various…”
Get full text

Clonal Kinetics and Single-Cell Transcriptional Profiles of T Cells Mobilized to Blood by Acute Exercise by ZÚÑIGA, TIFFANY M., BAKER, FORREST L., SMITH, KYLE A., BATATINHA, HELENA, LAU, BRANDEN, BURGESS, SHANE C., GUSTAFSON, MICHAEL P., KATSANIS, EMMANUEL, SIMPSON, RICHARD J.

“…Acute exercise redistributes large numbers of memory T cells, which may contribute to enhanced immune surveillance in regular exercisers. It is not known,…”
Get full text

Regulatory Dendritic Cells Induced by Bendamustine Are Associated With Enhanced Flt3 Expression and Alloreactive T-Cell Death by Molina, Megan S, Hoffman, Emely A, Stokes, Jessica, Kummet, Nicole, Smith, Kyle A, Baker, Forrest, Zúñiga, Tiffany M, Simpson, Richard J, Katsanis, Emmanuel

“…The growth factor Flt3 ligand (Flt3L) is central to dendritic cell (DC) homeostasis and development, controlling survival and expansion by binding to Flt3…”
Get full text

Aerobic fitness alters the capacity of mononuclear cells to produce pentraxin 3 following maximal exercise by Slusher, Aaron L., Zúñiga, Tiffany M., Acevedo, Edmund O.

“…Purpose Pentraxin 3 (PTX3) is a vital regulator of innate immune function. Although plasma PTX3 concentrations are elevated with aerobic fitness, the cellular…”
Get full text

Human lymphocytes mobilized with exercise have an anti-tumor transcriptomic profile and exert enhanced graft-versus-leukemia effects in xenogeneic mice by Batatinha, Helena, Diak, Douglass M, Niemiro, Grace M, Baker, Forrest L, Smith, Kyle A, Zúñiga, Tiffany M, Mylabathula, Preteesh L, Seckeler, Michael D, Lau, Branden, LaVoy, Emily C, Gustafson, Michael P, Katsanis, Emmanuel, Simpson, Richard J

“…Every bout of exercise mobilizes and redistributes large numbers of effector lymphocytes with a cytotoxic and tissue migration phenotype. The frequent…”
Get full text

Low sleep efficiency does not impact upper or lower limb vascular function in young adults by Scott, Matthew C., Hogwood, Austin C., Fralin, Richard C., Weggen, Jennifer B., Zúñiga, Tiffany M., Garten, Ryan S.

“…New Findings What is the central question of this study? We sought to investigate whether young adults reporting low sleep quality possessed lower vascular…”
Get full text

COVID-19 vaccination produces exercise-responsive SARS-CoV-2 specific T-cells regardless of infection history by Smith, Kyle A., Zúñiga, Tiffany M., Baker, Forrest L., Batatinha, Helena, Pedlar, Charles R., Burgess, Shane C., Gustafson, Michael P., Katsanis, Emmanuel, Simpson, Richard J.

“…•Acute exercise after vaccination robustly mobilized SARS-CoV-2–specific T-cells to blood in an intensity-dependent manner.•The synthetic immunity group…”
Get full text

Acute exercise increases immune responses to SARS CoV-2 in a previously infected man by Baker, Forrest L., Smith, Kyle A., Zúñiga, Tiffany M., Batatinha, Helena, Niemiro, Grace M., Pedlar, Charles R., Burgess, Shane C., Katsanis, Emmanuel, Simpson, Richard J.

“…Evidence is emerging that exercise and physical activity provides protection against severe COVID-19 disease in patients infected with SARS-CoV-2, but it is…”
Get full text

Exercise mobilizes diverse antigen specific T-cells and elevates neutralizing antibodies in humans with natural immunity to SARS CoV-2 by Baker, Forrest L., Zúñiga, Tiffany M., Smith, Kyle A., Batatinha, Helena, Kulangara, Terese S., Seckeler, Michael D., Burgess, Shane C., Katsanis, Emmanuel, Simpson, Richard J.

“…Epidemiological data suggest that physical activity protects against severe COVID-19 and improves clinical outcomes, but how exercise augments the SARS-CoV-2…”
Get full text

Exercise-induced β2-adrenergic Receptor Activation Enhances the Antileukemic Activity of Expanded γδ T-Cells via DNAM-1 Upregulation and PVR/Nectin-2 Recognition by Baker, Forrest L, Smith, Kyle A, Mylabathula, Preetesh L, Zúñiga, Tiffany M, Diak, Douglass M, Batatinha, Helena, Niemiro, Grace M, Seckeler, Michael D, Pedlar, Charles R, O'Connor, Daniel P, Colombo, Jamie, Katsanis, Emmanuel, Simpson, Richard J

“…Exercise mobilizes cytotoxic lymphocytes to blood which may allow superior cell products to be harvested and manufactured for cancer therapy. Gamma-Delta (γδ)…”
Get full text

Aerobic Training Status Enhances the Pentraxin 3-Mediated Innate Immune Response Following Maximal Exercise: 960 Board #221 May 30 3: 30 PM - 5: 00 PM by Slusher, Aaron L., Zúñiga, Tiffany M., Acevedo, Edmund O.

Get full text

Clonal Kinetics and Single-Cell Transcriptional Profiles of T Cells Mobilized to Blood by Acute Exercise by Zúñiga, Tiffany M., Baker, Forrest L., Smith, Kyle A., Batatinha, Helena, Lau, Branden, Burgess, Shane C., Gustafson, Michael P., Katsanis, Emmanuel, Simpson, Richard J.

Get full text

Acute Exercise Mobilizes Functional SARS-CoV-2 Specific T-Cells And Elevates Neutralizing Antibodies In Previously Infected Individuals: 1265 by Baker, Forrest L., Smith, Kyle A., Zúñiga, Tiffany M., Batatinha, Helena, Pedlar, Charles R., Burgess, Shane C., Katsanis, Emmanuel, Simpson, Richard J.

Get full text

Acute Exercise Mobilizes Functional SARS-CoV-2 Specific T-Cells And Elevates Neutralizing Antibodies In Previously Infected Individuals: 1265 by Baker, Forrest L., Smith, Kyle A., Zúñiga, Tiffany M., Batatinha, Helena, Pedlar, Charles R., Burgess, Shane C., Katsanis, Emmanuel, Simpson, Richard J.

Get full text

Human Lymphocytes Mobilized With Exercise Extend Survival And Lower Leukemic Burden In Xenogeneic Mice: 1134 by Batatinha, Helena, Diak, Douglass M., Niemiro, Grace M., Mylabathula, Preteesh, Baker, Forrest L., Smith, Kyle A., Zúñiga, Tiffany M., Park, Yoonjung, LaVoy, Emily C., Katsanis, Emmanuel, Simpson, Richard J.

Get full text