Search Results - "Yusoff, Nur Zahirah binte M."
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Isolation and Propagation of Human Corneal Stromal Keratocytes for Tissue Engineering and Cell Therapy
Published in Cells (Basel, Switzerland) (05-01-2022)“…The human corneal stroma contains corneal stromal keratocytes (CSKs) that synthesize and deposit collagens and keratan sulfate proteoglycans into the stromal…”
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Combined Therapy Using Human Corneal Stromal Stem Cells and Quiescent Keratocytes to Prevent Corneal Scarring after Injury
Published in International journal of molecular sciences (01-07-2022)“…Corneal blindness due to scarring is conventionally treated by corneal transplantation, but the shortage of donor materials has been a major issue affecting…”
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Decellularization of human stromal refractive lenticules for corneal tissue engineering
Published in Scientific reports (23-05-2016)“…Small incision lenticule extraction (SMILE) becomes a procedure to correct myopia. The extracted lenticule can be used for other clinical scenarios. To prepare…”
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Impact of keratocyte differentiation on corneal opacity resolution and visual function recovery in male rats
Published in Nature communications (11-06-2024)“…Intrastromal cell therapy utilizing quiescent corneal stromal keratocytes (qCSKs) from human donor corneas emerges as a promising treatment for corneal…”
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Mesenchymal Stem Cell Exosomes as Immunomodulatory Therapy for Corneal Scarring
Published in International journal of molecular sciences (01-04-2023)“…Corneal scarring is a leading cause of worldwide blindness. Human mesenchymal stem cells (MSC) have been reported to promote corneal wound healing through…”
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Postnatal periodontal ligament as a novel adult stem cell source for regenerative corneal cell therapy
Published in Journal of cellular and molecular medicine (01-06-2018)“…Corneal opacities are a leading cause of global blindness. They are conventionally treated by the transplantation of donor corneal tissue, which is, restricted…”
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Experiment-Based Validation of Corneal Lenticule Banking in a Health Authority-Licensed Facility
Published in Tissue engineering. Part A (01-01-2022)“…With the expected rise in patients undergoing refractive lenticule extraction worldwide, the number of discarded corneal stromal lenticules will increase…”
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Ex Vivo Propagation of Human Corneal Stromal "Activated Keratocytes" for Tissue Engineering
Published in Cell transplantation (01-09-2015)“…Keratoconus is a corneal disorder characterized by a thinning of stromal tissue, and the affected patients have induced astigmatism and visual impairment. It…”
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Effect of corneal stromal lenticule customization on neurite distribution and excitatory property
Published in Journal of advanced research (01-05-2022)“…A Schematic overview of this study from the SMILE lenticule creation and extraction to lenticule customization: excimer laser reshaping/thinning, ultraviolet A…”
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Characterization of Human Transition Zone Reveals a Putative Progenitor-Enriched Niche of Corneal Endothelium
Published in Cells (Basel, Switzerland) (12-10-2019)“…The corneal endothelium regulates corneal hydration to maintain the transparency of cornea. Lacking regenerative capacity, corneal endothelial cell loss due to…”
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Electron beam-irradiated donor cornea for on-demand lenticule implantation to treat corneal diseases and refractive error
Published in Acta biomaterialia (01-10-2023)“…The cornea is the major contributor to the refractive power of the eye, and corneal diseases are a leading cause of reversible blindness. The main treatment…”
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Safety and Feasibility of Intrastromal Injection of Cultivated Human Corneal Stromal Keratocytes as Cell-Based Therapy for Corneal Opacities
Published in Investigative ophthalmology & visual science (02-07-2018)“…To evaluate the safety and feasibility of intrastromal injection of human corneal stromal keratocytes (CSKs) and its therapeutic effect on a rodent early…”
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Nerve regeneration by human corneal stromal keratocytes and stromal fibroblasts
Published in Scientific reports (28-03-2017)“…Laser refractive surgeries reshape corneal stroma to correct refractive errors, but unavoidably affect corneal nerves. Slow nerve regeneration and atypical…”
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