Search Results - "Yusef, Yamil R"
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Voltage-dependent and -independent titration of specific residues accounts for complex gating of a ClC chloride channel by extracellular protons
Published in The Journal of physiology (01-04-2009)“…The ClC transport protein family comprises both Cl â ion channel and H + /Cl â and H + /NO 3 â exchanger members. Structural studies on a bacterial ClC…”
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2
A SNAP-25 cleaving chimera of botulinum neurotoxin /A and /E prevents TNFα−induced elevation of the activities of native TRP channels on early postnatal rat dorsal root ganglion neurons
Published in Neuropharmacology (01-08-2018)“…Transient receptor potential (TRP) vallinoid 1 (TRPV1) and ankyrin 1 (TRPA1) are two transducing channels expressed on peripheral sensory nerves involved in…”
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3
Removal of gating in voltage-dependent ClC-2 chloride channel by point mutations affecting the pore and C-terminus CBS-2 domain
Published in The Journal of physiology (01-04-2006)“…Functional and structural studies demonstrate that Cl â channels of the ClC family have a dimeric double-barrelled structure, with each monomer contributing…”
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Aldosterone-induced ENaC and basal Na+/K+-ATPase trafficking via protein kinase D1-phosphatidylinositol 4-kinaseIIIβ trans Golgi signalling in M1 cortical collecting duct cells
Published in Molecular and cellular endocrinology (15-06-2013)“…•Aldosterone induces rapid PKD1-dependent ENaCγ membrane trafficking in M1 cells.•Na+/K+-ATPase activity and localization is impaired in shRNA-PKD1 knockdown…”
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5
Physiological techniques in the study of rapid aldosterone effects
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2014)“…Molecular imaging and electrophysiological techniques are powerful tools to analyze the responses stimulated by aldosterone and other hormones in target…”
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Estrogen regulation of epithelial ion transport: Implications in health and disease
Published in Steroids (01-08-2012)“…[Display omitted] ► Ion transport responses to estrogen in epithelia are female sex-specific. ► The anti-secretory effects of estrogen underlie extracellular…”
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Estrogen increases ENaC activity via PKCδ signaling in renal cortical collecting duct cells
Published in Physiological reports (01-05-2014)“…The most active estrogen, 17β‐estradiol (E2), has previously been shown to stimulate a female sex‐specific antisecretory response in the intestine. This effect…”
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8
Protein kinase D1 modulates aldosterone-induced ENaC activity in a renal cortical collecting duct cell line
Published in Molecular and cellular endocrinology (30-08-2010)“…Aldosterone treatment of M1-CCD cells stimulated an increase in epithelial Na + channel (ENaC) α-subunit expression that was mainly localized to the apical…”
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9
Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: Role of a tyrosine endocytosis motif in surface retrieval
Published in Journal of cellular physiology (01-12-2009)“…ClC‐2 chloride channel is present in the brain and some transporting epithelia where its function is poorly understood. We have now demonstrated that the…”
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10
Functional evaluation of human ClC-2 chloride channel mutations associated with idiopathic generalized epilepsies
Published in Physiological genomics (16-09-2004)“…Centro de Estudios Científicos, Valdivia, Chile The ClC-2 Cl channel has been postulated to play a role in the inhibitory GABA response in neurons or to…”
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11
Aldosterone-induced ENaC and basal Na super(+)/K super(+)-ATPase trafficking via protein kinase D1-phosphatidylinositol 4-kinaseIII beta trans Golgi signalling in M1 cortical collecting duct cells
Published in Molecular and cellular endocrinology (01-06-2013)“…Aldosterone regulates Na super(+) transport in the distal nephron through multiple mechanisms that include the transcriptional control of epithelial sodium…”
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12
Estrogen increases EN aC activity via PKC δ signaling in renal cortical collecting duct cells
Published in Physiological reports (01-05-2014)“…The most active estrogen, 17β‐estradiol (E2), has previously been shown to stimulate a female sex‐specific antisecretory response in the intestine. This effect…”
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