Esophageal achalasia: possible pathogenic concepts from the perspective of modern notions

Esophageal achalasia is an esophageal motility disease characterized by impaired relaxation of lower esophageal sphincter (LES) and severe clinical symptoms. The main etiological factors and other essential aspects of pathogenesis and progression of this disorder are actively studied. To date, the q...

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Bibliographic Details
Published in:	Hirurgija (Moskva) no. 5; p. 104
Main Authors:	Gallyamov, E A, Erin, S A, Burmistrov, A I, Chicherina, M A, Gololobov, G Yu, Yurkuliev, N A
Format:	Journal Article
Language:	English Russian
Published:	Russia (Federation) 2021
Subjects:	Esophageal Achalasia - diagnosis Esophageal Achalasia - etiology Esophageal Sphincter, Lower Humans Manometry pathogenesis of progressive cardiospasm viruses and achalasia esophageal achalasia autoimmunity and characteristic changes of the esophagus
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Summary:	Esophageal achalasia is an esophageal motility disease characterized by impaired relaxation of lower esophageal sphincter (LES) and severe clinical symptoms. The main etiological factors and other essential aspects of pathogenesis and progression of this disorder are actively studied. To date, the question of significance of etiological factors is experimental and requires further study. In this review, the authors analyzed and summarized the modern data on etiology and pathogenesis of this disease considering the new researches devoted to this issue.
ISSN:	0023-1207
DOI:	10.17116/hirurgia2021051104