Search Results - "Yunna, Chen"

Macrophage M1/M2 polarization by Yunna, Chen, Mengru, Hu, Lei, Wang, Weidong, Chen

“…Macrophages can be affected by a variety of factors to change their phenotype and thus affect their function. Activated macrophages are usually divided into…”
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Carbon dots derived from Poria cocos polysaccharide as an effective “on-off” fluorescence sensor for chromium (VI) detection by Huang, Qianqian, Bao, Qianqian, Wu, Chengyuan, Hu, Mengru, Chen, Yunna, Wang, Lei, Chen, Weidong

“…Chromium is a harmful contaminant showing mutagenicity and carcinogenicity. Therefore, detection of chromium requires the development of low-cost and…”
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Emerging strategies against tumor-associated fibroblast for improved the penetration of nanoparticle into desmoplastic tumor by Yunna, Chen, Mengru, Hu, Fengling, Wang, Lei, Wang, Weidong, Chen

“…[Display omitted] The therapeutic effect of nanoparticles is limited in solid tumors, especially desmoplastic tumors, because the tumor matrix hinders the…”
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Preparation of 5-fluorouracil-loaded chitosan nanoparticles and study of the sustained release in vitro and in vivo by Sun, Li, Chen, Yunna, Zhou, Yali, Guo, Dongdong, Fan, Yufan, Guo, Fangyan, Zheng, Yufeng, Chen, Weidong

“…The nanoparticles were prepared by chitosan as carrier and were characterized. In addition, in vitro release studies and in vivo pharmacokinetic studies of…”
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Enhancing cancer immunotherapy: Nanotechnology-mediated immunotherapy overcoming immunosuppression by Chen, Yunna, Zhou, Qianqian, Jia, Zongfang, Cheng, Nuo, Zhang, Sheng, Chen, Weidong, Wang, Lei

“…Immunotherapy is an important cancer treatment method that offers hope for curing cancer patients. While immunotherapy has achieved initial success, a major…”
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Tumor-Derived Extracellular Vesicles Regulate Cancer Progression in the Tumor Microenvironment by Bao, Qianqian, Huang, Qianqian, Chen, Yunna, Wang, Qiang, Sang, Ran, Wang, Lei, Xie, Ying, Chen, Weidong

“…Extracellular vesicles (EVs) are nanosized particles released by numerous kinds of cells, which are now increasingly considered as essential vehicles of…”
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Paeoniflorin alleviates 17α-ethinylestradiol-induced cholestasis via the farnesoid X receptor-mediated bile acid homeostasis signaling pathway in rats by Wang, Rulin, Yuan, Tengteng, Sun, Jing, Yang, Menghuan, Chen, Yunna, Wang, Lei, Wang, Yanyan, Chen, Weidong, Peng, Daiyin

“…Cholestasis, characterized by disturbance of bile formation, is a common pathological condition that can induce several serious liver diseases. As a kind of…”
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Effects of mulberry leaf extracts on activity and mRNA expression of five cytochrome P450 enzymes in rat by Sheng, Chenming, Shi, Xiaoyan, Ding, Zexian, Chen, Yunna, Shi, Xiaoqian, Wu, Yifan, Zhang, Wenjing, Chen, Weidong

“…Adverse side effects of drug-drug interactions induced by human cytochrome P450 (CYP450) inhibition is an important consideration in drug discovery. Mulberry…”
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Activation/Inactivation of Anticancer Drugs by CYP3A4: Influencing Factors for Personalized Cancer Therapy by Wang, Fengling, Zhang, Xue, Wang, Yanyan, Chen, Yunna, Lu, Huiyu, Meng, Xiangyun, Ye, Xi, Chen, Weidong

“…Cytochrome P450 3A4 (CYP3A4), one of the most important members of the cytochrome P450 subfamily, is a crucial catalyst in the metabolism of numerous drugs. As…”
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Activation of CYP3A by Accelerated Blood Clearance Phenomenon Potentiates the Hepatocellular Carcinoma-Targeting Therapeutic Effects of PEGylated Anticancer Prodrug Liposomes by Zhang, Xue, Pan, Jianquan, Ye, Xi, Chen, Yunna, Wang, Lei, Meng, Xiangyun, Chen, Weidong, Wang, Fengling

“…Reduced enzyme activity in hepatocellular carcinoma (HCC) and poor targeting limit the application of enzyme-activating prodrugs, which is also detrimental to…”
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Salvianolic acid B-loaded polydopamine-modified hollow mesoporous organic silica nanoparticles for treatment of breast cancer metastasis via suppressing cancer-associated fibroblasts by Hu, Mengru, Cheng, Nuo, Wang, Siwei, Li, Ruoqing, Liu, Yu, Wang, Lei, Chen, Weidong, Chen, Yunna

“…Drug Delivery System was constructed using dopamine-coated organic-inorganic hybrid hollow mesoporous organic silica nanoparticles (HMON-PDA) as drug carriers…”
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Dendrobium huoshanense in the treatment of ulcerative colitis: Network pharmacology and experimental validation by Yao, Liang, Fang, Jing, Zhao, Junwei, Yu, Jiao, Zhang, Xiaoqian, Chen, Weidong, Han, Lan, Peng, Daiyin, Chen, Yunna

“…Dendrobium huoshanense C. Z. Tang et S. J. Cheng (DH) is a traditional medicinal herb with a long history of medicinal use. DH has been recorded as protecting…”
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Nano-delivery of salvianolic acid B induces the quiescence of tumor-associated fibroblasts via interfering with TGF-β1/Smad signaling to facilitate chemo- and immunotherapy in desmoplastic tumor by Chen, Yunna, Hu, Mengru, Wang, Siwei, Wang, Qiang, Lu, Huiyu, Wang, Fengling, Wang, Lei, Peng, Daiyin, Chen, Weidong

“…[Display omitted] As the key stromal cells that mediate the desmoplastic reaction, tumor-associated fibroblasts (TAFs) play a critical role in the limited…”
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Co-delivery of hypoxia inducible factor-1[alpha] small interfering RNA and 5-fluorouracil to overcome drug resistance in gastric cancer SGC-7901 cells by Chen, Yunna, Sun, Li, Guo, Dongdong, Wu, Ziteng, Chen, Weidong

“…Background Drug resistance cancer cells have become a major problem in chemotherapy. To solve this problem, the co-delivery of small interefering RNA (siRNA)…”
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Co‐delivery of hypoxia inducible factor‐1α small interfering RNA and 5‐fluorouracil to overcome drug resistance in gastric cancer SGC‐7901 cells by Chen, Yunna, Sun, Li, Guo, Dongdong, Wu, Ziteng, Chen, Weidong

“…Background Drug resistance cancer cells have become a major problem in chemotherapy. To solve this problem, the co‐delivery of small interefering RNA (siRNA)…”
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Acidity and Glutathione Dual‐Responsive Polydopamine‐Coated Organic‐Inorganic Hybrid Hollow Mesoporous Silica Nanoparticles for Controlled Drug Delivery by Chen, Qi, Chen, Yunna, Zhang, Wenjing, Huang, Qianqian, Hu, Mengru, Peng, Daiyin, Peng, Can, Wang, Lei, Chen, Weidong

“…Controversial biodegradability and nonspecific pre‐drug leakage are major limitations for inorganic nanoparticles in cancer treatment. To solve these problems,…”
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Lotus Root-Like SiO2 Nanofibers for High-Temperature Flexible Thermal Insulation by Li, Qingyang, Zhang, Wenlu, Chen, Yunna, Li, Wenbin, He, Chong

“…Large-scale spinning of high-performance SiO2 porous nanofibers remains a pivotal challenge in facilitating their utilization for flexible thermal insulation…”
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Construction and Biological Evaluation of Multiple Modification Hollow Mesoporous Silicone Doxorubicin Nanodrug Delivery System by Hu, Mengru, Zhang, Wenjing, Chen, Weidong, Chen, Yunna, Huang, Qianqian, Bao, Qianqian, Lin, Tongyuan, Wang, Lei, Zhang, Shantang

“… The combination of functionalized nanoparticles and chemotherapy drugs can effectively target tumor tissue, which can improve efficacy and reduce toxicity…”
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Polymer Blend Blow Spinning of Flexible Porous Carbon Nanofibers Capable for Multiapplication by Zhang, Wenlu, Song, Chao, Li, Qingyang, Chen, Yunna, Li, Wenbin, He, Chong

“…Highly efficient production of porous carbon nanofibers (PCNFs) is indispensable for applications in adsorption, thermal insulation, catalysis, batteries, etc…”
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A rapid and efficient technique for liposomal and nonliposomal drug pharmacokinetics studies using magnetic nanoprobes and its application to leakage kinetics of liposomes by Chen, Yunna, Wang, Lei, Guo, Dongdong, Sheng, Chenming, Dai, Haozhi, Shi, Xiaoyan, Zhang, Wenjing, Huang, Qianqian, Peng, Can, Chen, Weidong

“…•SA-Fe3O4@PDA are first used to isolate liposomal and non-liposomal drug.•SA-Fe3O4@PDA were successfully used for the separation of liposome in…”
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