Search Results - "Yung, Theodora"

Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals by Yung, Theodora, Poon, Frankie, Liang, Minggao, Coquenlorge, Sabrina, McGaugh, Emily C., Hui, Chi-chung, Wilson, Michael D., Nostro, M. Cristina, Kim, Tae-Hee

“…Human embryonic stem cell-derived beta cells offer a promising cell-based therapy for diabetes. However, efficient stem cell to beta cell differentiation has…”
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Single-cell chromatin profiling of the primitive gut tube reveals regulatory dynamics underlying lineage fate decisions by Smith, Ryan J., Zhang, Hongpan, Hu, Shengen Shawn, Yung, Theodora, Francis, Roshane, Lee, Lilian, Onaitis, Mark W., Dirks, Peter B., Zang, Chongzhi, Kim, Tae-Hee

“…Development of the gastrointestinal system occurs after gut tube closure, guided by spatial and temporal control of gene expression. However, it remains…”
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Epigenetic control of cellular crosstalk defines gastrointestinal organ fate and function by Smith, Ryan J., Liang, Minggao, Loe, Adrian Kwan Ho, Yung, Theodora, Kim, Ji-Eun, Hudson, Matthew, Wilson, Michael D., Kim, Tae-Hee

“…Epithelial-mesenchymal signaling in the gastrointestinal system is vital in establishing regional identity during organogenesis and maintaining adult stem cell…”
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GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis by Coquenlorge, Sabrina, Yin, Wen-Chi, Yung, Theodora, Pan, Jingyi, Zhang, Xiaoyun, Mo, Rong, Belik, Jaques, Hui, Chi-Chung, Kim, Tae-Hee

“…Gut mesenchyme provides key stem cell niche signals such as Wnt ligands, but how these signals are regulated is unclear. Because Hedgehog (Hh) signaling is…”
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IRX3/5 regulate mitotic chromatid segregation and limb bud shape by Tao, Hirotaka, Lambert, Jean-Philippe, Yung, Theodora M, Zhu, Min, Hahn, Noah A, Li, Danyi, Lau, Kimberly, Sturgeon, Kendra, Puviindran, Vijitha, Zhang, Xiaoyun, Gong, Wuming, Chen, Xiao Xiao, Anderson, Gregory, Garry, Daniel J, Henkelman, R Mark, Sun, Yu, Iulianella, Angelo, Kawakami, Yasuhiko, Gingras, Anne-Claude, Hui, Chi-Chung, Hopyan, Sevan

“…Pattern formation is influenced by transcriptional regulation as well as by morphogenetic mechanisms that shape organ primordia, although factors that link…”
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A fibronectin gradient remodels mixed-phase mesoderm by Zhu, Min, Gu, Bin, Thomas, Evan C, Huang, Yunyun, Kim, Yun-Kyo, Tao, Hirotaka, Yung, Theodora M, Chen, Xin, Zhang, Kaiwen, Woolaver, Elizabeth K, Nevin, Mikaela R, Huang, Xi, Winklbauer, Rudolph, Rossant, Janet, Sun, Yu, Hopyan, Sevan

“…Physical processes ultimately shape tissue during development. Two emerging proposals are that cells migrate toward stiffer tissue (durotaxis) and that the…”
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Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer by Francis, Roshane, Guo, Haiyang, Streutker, Catherine, Ahmed, Musaddeque, Yung, Theodora, Dirks, Peter B, He, Housheng Hansen, Kim, Tae-Hee

“…Transcription factors (TFs) are spatially and temporally regulated during gut organ specification. Although accumulating evidence shows aberrant reactivation…”
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Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion by Polsani, Nikaya, Yung, Theodora, Thomas, Evan, Phung-Rojas, Melissa, Gupta, Isha, Denker, Julie, Lau, Kimberly, Feng, Xiaotian, Ibarra, Beatriz, Hopyan, Sevan, Atit, Radhika P

“…Apical expansion of calvarial osteoblast progenitors from the cranial mesenchyme (CM) above the eye is integral to calvarial growth and enclosure of the brain…”
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Multifaceted Control of Pancreatic Development by Mesenchymal Regulators of Hedgehog Signaling by Yung, Theodora

“…Pancreatic development is coordinated by signaling pathways through dynamic epithelial-mesenchymal interactions that remain poorly understood. My work…”
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IRX3/5 regulate mitotic chromatid segregation and limb bud shape by Tao, Hirotaka, Lambert, Jean-Philippe, Yung, Theodora M, Zhu, Min, Hahn, Noah A, Li, Danyi, Lau, Kimberly, Sturgeon, Kendra, Puviindran, Vijitha, Zhang, Xiaoyun, Gong, Wuming, Chen, Xiao Xiao, Anderson, Gregory, Garry, Daniel J, Henkelman, R Mark, Sun, Yu, Iulianella, Angelo, Kawakami, Yasuhiko, Gingras, Anne-Claude, Hui, Chi-Chung, Hopyan, Sevan

“…Pattern formation is influenced by transcriptional regulation as well as by morphogenetic mechanisms that shape organ primordia, although factors that link…”
Get full text