Search Results - "Yung, Amanda W.Y."

Platelets Play Differential Role During the Initiation and Progression of Autoimmune Neuroinflammation by Starossom, Sarah C, Veremeyko, Tatyana, Yung, Amanda W.Y, Dukhinova, Marina, Au, Cheryl, Lau, Alexander Y, Weiner, Howard L, Ponomarev, Eugene D

“…RATIONALE:Platelets are known to participate in vascular pathologies; however, their role in neuroinflammatory diseases, such as multiple sclerosis (MS), is…”
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ASD-like behaviors, a dysregulated inflammatory response and decreased expression of PLP1 characterize mice deficient for sialyltransferase ST3GAL5 by Strekalova, Tatyana, Svirin, Evgeniy, Veniaminova, Ekaterina, Kopeikina, Ekaterina, Veremeyko, Tatyana, Yung, Amanda W.Y., Proshin, Andrey, Walitza, Susanne, Anthony, Daniel C., Lim, Lee Wei, Lesch, Klaus-Peter, Ponomarev, Eugene D.

“…Gangliosides are glycosphingolipids, which are abundant in brain, are known to modulate ion channels and cell-to-cell communication. Deficiencies can result in…”
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Expression of cAMP-responsive element binding proteins (CREBs) in fast- and slow-twitch muscles: A signaling pathway to account for the synaptic expression of collagen-tailed subunit (ColQ) of acetylcholinesterase at the rat neuromuscular junction by Choi, Roy C.Y., Chen, Vicky P., Luk, Wilson K.W., Yung, Amanda W.Y., Ng, Alice H.M., Dong, Tina T.X., Tsim, Karl W.K.

“…► ColQ-1 and ColQ-1a mRNAs are differentially expressed in fast- and slow-twitch muscles. ► In slow-twitch muscles phosphorylated CREB (P-CREB) is abundant. ►…”
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Early Growth Response Gene-2 Is Essential for M1 and M2 Macrophage Activation and Plasticity by Modulation of the Transcription Factor CEBPβ by Veremeyko, Tatyana, Yung, Amanda W Y, Anthony, Daniel C, Strekalova, Tatyana, Ponomarev, Eugene D

“…The process of macrophage polarization is involved in many pathologies such as anti-cancer immunity and autoimmune diseases. Polarized macrophages exhibit…”
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Platelets promote epileptic seizures by modulating brain serotonin level, enhancing neuronal electric activity, and contributing to neuroinflammation and oxidative stress by Kopeikina, Ekaterina, Dukhinova, Marina, Yung, Amanda W.Y., Veremeyko, Tatyana, Kuznetsova, Inna S., Lau, Thomas Y.B., Levchuk, Kseniia, Ponomarev, Eugene D.

“…[Display omitted] •Platelets substantially contribute to the severity of epileptic seizures.•During epileptic seizures, platelets enter CNS and secrete…”
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Fresh evidence for major brain gangliosides as a target for the treatment of Alzheimer's disease by Dukhinova, Marina, Veremeyko, Tatyana, Yung, Amanda W.Y., Kuznetsova, Inna S., Lau, Thomas Y.B., Kopeikina, Ekaterina, Chan, Andrew M.L., Ponomarev, Eugene D.

“…Although it was suggested that gangliosides play an important role in the binding of amyloid fragments to neuronal cells, the exact role of gangliosides in…”
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Cyclic AMP Pathway Suppress Autoimmune Neuroinflammation by Inhibiting Functions of Encephalitogenic CD4 T Cells and Enhancing M2 Macrophage Polarization at the Site of Inflammation by Veremeyko, Tatyana, Yung, Amanda W Y, Dukhinova, Marina, Kuznetsova, Inna S, Pomytkin, Igor, Lyundup, Alexey, Strekalova, Tatyana, Barteneva, Natasha S, Ponomarev, Eugene D

“…Although it has been demonstrated that cAMP pathway affect both adaptive and innate cell functions, the role of this pathway in the regulation of…”
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Platelets mediate protective neuroinflammation and promote neuronal plasticity at the site of neuronal injury by Dukhinova, Marina, Kuznetsova, Inna, Kopeikina, Ekaterina, Veniaminova, Ekaterina, Yung, Amanda W.Y., Veremeyko, Tatyana, Levchuk, Kseniia, Barteneva, Natasha S., Wing-Ho, Kenny Kam, Yung, Wing-Ho, Liu, Julia Y.H., Rudd, John, Yau, Sonata S.Y., Anthony, Daniel C., Strekalova, Tatyana, Ponomarev, Eugene D.

“…•Glycolipid-deficient mice exhibit deficits in neuronal function after injury.•Brain glycolipids induce platelet activation after traumatic brain…”
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The Role of Neuronal Factors in the Epigenetic Reprogramming of Microglia in the Normal and Diseased Central Nervous System by Veremeyko, Tatyana, Yung, Amanda W. Y., Dukhinova, Marina, Strekalova, Tatyana, Ponomarev, Eugene D.

“…Twenty years ago, the scientific community exhibited relatively little interest in the study of microglial cells. However, recent technical and conceptual…”
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Glatiramer acetate (copaxone) modulates platelet activation and inhibits thrombin-induced calcium influx: possible role of copaxone in targeting platelets during autoimmune neuroinflammation by Starossom, Sarah C, Veremeyko, Tatyana, Dukhinova, Marina, Yung, Amanda W Y, Ponomarev, Eugene D

“…Glatiramer acetate (GA, Copaxone, Copolymer-1) is an FDA approved drug for the treatment of MS and it is very effective in suppressing neuroinflammation in…”
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Sex-Specific ADHD-like Behaviour, Altered Metabolic Functions, and Altered EEG Activity in Sialyltransferase ST3GAL5-Deficient Mice by Strekalova, Tatyana, Veniaminova, Ekaterina, Svirin, Evgeniy, Kopeikina, Ekaterina, Veremeyko, Tatyana, Yung, Amanda W Y, Proshin, Andrey, Tan, Shawn Zheng Kai, Khairuddin, Sharafuddin, Lim, Lee Wei, Lesch, Klaus-Peter, Walitza, Susanne, Anthony, Daniel C, Ponomarev, Eugene D

“…A deficiency in GM3-derived gangliosides, resulting from a lack of lactosylceramide-alpha-2,3-sialyltransferase (ST3GAL5), leads to severe neuropathology,…”
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Synergistic Action of Flavonoids, Baicalein, and Daidzein in Estrogenic and Neuroprotective Effects : A Development of Potential Health Products and Therapeutic Drugs against Alzheimer’s Disease by Choi, Roy Chi-Yan, Zhu, Judy T. T., Yung, Amanda W. Y., Lee, Pinky S. C., Xu, Sherry Li, Guo, Ava J. Y., Zhu, Kevin Y., Dong, Tina Ting-Xia, Tsim, Karl Wah-Keung

“…Despite the classical hormonal effect, estrogen has been reported to mediate neuroprotection in the brain, which leads to the searching of estrogen-like…”
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