Search Results - "Yunchao, Huang"
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High-resolution metabolomic biomarkers for lung cancer diagnosis and prognosis
Published in Scientific reports (03-06-2021)“…Lung cancer is the leading cause of human cancer mortality due to the lack of early diagnosis technology. The low-dose computed tomography scan (LDCT) is one…”
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Clinical and biomarker analyses of sintilimab versus chemotherapy as second-line therapy for advanced or metastatic esophageal squamous cell carcinoma: a randomized, open-label phase 2 study (ORIENT-2)
Published in Nature communications (14-02-2022)“…This randomized, open-label, multi-center phase 2 study (NCT03116152) assessed sintilimab, a PD-1 inhibitor, versus chemotherapy in patients with esophageal…”
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YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression
Published in Nature communications (25-10-2019)“…Hypoxia occurs naturally at high-altitudes and pathologically in hypoxic solid tumors. Here, we report that genes involved in various human cancers evolved…”
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Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (LUX-Lung 6): an open-label, randomised phase 3 trial
Published in The lancet oncology (01-02-2014)“…Summary Background Afatinib—an oral irreversible ErbB family blocker—improves progression-free survival compared with pemetrexed and cisplatin for first-line…”
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EphA2: A promising therapeutic target in breast cancer
Published in Journal of genetics and genomics (20-04-2021)“…Ephrin type-A receptor 2 (EphA2), a receptor tyrosine kinase, is overexpressed in human breast cancers often linked to poor patient prognosis. Accumulating…”
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Biodegradable Nanofibrillated Cellulose/Poly-(butylene adipate-co-terephthalate) Composite Film with Enhanced Barrier Properties for Food Packaging
Published in Molecules (Basel, Switzerland) (16-03-2023)“…Biodegradable composites consisting of Poly-(butylene adipate-co-terephthalate) (PBAT), thermoplastic starch, hydrophobically modified nanofibrillated…”
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Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials
Published in The lancet oncology (01-02-2015)“…Summary Background We aimed to assess the effect of afatinib on overall survival of patients with EGFR mutation-positive lung adenocarcinoma through an…”
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FAPI-PET/CT in Cancer Imaging: A Potential Novel Molecule of the Century
Published in Frontiers in oncology (25-05-2022)“…Fibroblast activation protein (FAP), a type II transmembrane serine protease, is highly expressed in more than 90% of epithelial tumors and is closely…”
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9
Overexpression of lncRNA IGFBP4-1 reprograms energy metabolism to promote lung cancer progression
Published in Molecular cancer (25-09-2017)“…Reprogrammed energy metabolism as an emerging hallmark of cancer has recently drawn special attention since it facilitate cell growth and proliferation…”
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MicroRNA-195 inhibits non-small cell lung cancer cell proliferation, migration and invasion by targeting MYB
Published in Cancer letters (28-05-2014)“…Abstract MicroRNA-195 (miR-195) has been implicated in several other cancers; however, its role in non-small cell lung cancer (NSCLC) remains unclear. In this…”
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Effects of lipid emulsions on the formation of Escherichia coli–Candida albicans mixed-species biofilms on PVC
Published in Scientific reports (19-08-2021)“…Patients receiving lipid emulsions are at increased risk of contracting catheter-related bloodstream infections (CRBSIs) in the clinic. More than 15% of CRBSIs…”
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Influence of pre-transplant minimal residual disease on prognosis after Allo-SCT for patients with acute lymphoblastic leukemia: systematic review and meta-analysis
Published in BMC cancer (23-07-2018)“…This meta-analysis was performed to explore the impact of minimal residual disease (MRD) prior to transplantation on the prognosis for patients with acute…”
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Mxi1 participates in the progression of lung cancer via the microRNA-300/KLF9/GADD34 Axis
Published in Cell death & disease (02-05-2022)“…The purpose of the current study was to define the role of MAX interactor 1 (Mxi1) in the pathogenesis of lung cancer and its underlying molecular mechanism…”
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Inhibitory effect of Disulfiram/copper complex on non-small cell lung cancer cells
Published in Biochemical and biophysical research communications (18-04-2014)“…•Disulfiram and copper synergistically inhibit lung cancer cell proliferation.•Lung cancer cell colony formation ability is inhibited by…”
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15
The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry
Published in Signal transduction and targeted therapy (03-11-2021)“…The scope and variety of the metabolic intermediates from the mitochondrial tricarboxylic acid (TCA) cycle that are engaged in epigenetic regulation of the…”
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Constituents of Household Air Pollution and Risk of Lung Cancer among Never-Smoking Women in Xuanwei and Fuyuan, China
Published in Environmental health perspectives (01-09-2019)“…Lung cancer rates among never-smoking women in Xuanwei and Fuyuan in China are among the highest in the world and have been attributed to the domestic use of…”
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EGFR mutation detection in circulating cell-free DNA of lung adenocarcinoma patients: analysis of LUX-Lung 3 and 6
Published in British journal of cancer (17-01-2017)“…Background: In the Phase III LUX-Lung 3/6 (LL3/LL6) trials in epidermal growth factor receptor ( EGFR ) mutation-positive lung adenocarcinoma patients, we…”
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The D-dimer level predicts the prognosis in patients with lung cancer: a systematic review and meta-analysis
Published in Journal of cardiothoracic surgery (28-08-2021)“…Abstract Objective Although the significance of increased plasma D-dimer levels in activating coagulation and fibrinolysis has been reported, it is still…”
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Serum cholinesterase may independently predict prognosis in non-small-cell lung cancer
Published in BMC cancer (21-01-2022)“…Serum cholinesterase (ChE) was found to be involved in cancer initiation and progression. However, the survival association between serum ChE and non-small…”
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CAR‐T cell therapy for lung cancer: Potential and perspective
Published in Thoracic cancer (01-04-2022)“…Lung cancer is the highest incidence and mortality of all cancers around the world. In the present immunotherapy era, an increasing number of immunotherapeutic…”
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