Search Results - "Yun, Yaejin"

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    Cryo-EM structure of human class C orphan GPCR GPR179 involved in visual processing by Yun, Yaejin, Jeong, Hyeongseop, Laboute, Thibaut, Martemyanov, Kirill A., Lee, Hyung Ho

    Published in Nature communications (27-09-2024)
    “…GPR179, an orphan class C GPCR, is expressed at the dendritic tips of ON-bipolar cells in the retina. It plays a pivotal role in the initial synaptic…”
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    Journal Article
  3. 3

    Biochemical Characterization of the Num1-Mdm36 Complex at the Mitochondria-Plasma Membrane Contact Site by Won, Jongdae, Choi, Yuri, Yun, Yaejin, Lee, Hyung Ho

    Published in Molecules and cells (30-04-2021)
    “…that tethers mitochondria to the plasma membrane and plays a key role in mitochondrial fission. The main components of MECA are Num1 and Mdm36, and it is known…”
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    Identifying a key spot for electron mediator-interaction to tailor CO dehydrogenase’s affinity by Kim, Suk Min, Kang, Sung Heuck, Lee, Jinhee, Heo, Yoonyoung, Poloniataki, Eleni G., Kang, Jingu, Yoon, Hye-Jin, Kong, So Yeon, Yun, Yaejin, Kim, Hyunwoo, Ryu, Jungki, Lee, Hyung Ho, Kim, Yong Hwan

    Published in Nature communications (28-03-2024)
    “…Fe‒S cluster-harboring enzymes, such as carbon monoxide dehydrogenases (CODH), employ sophisticated artificial electron mediators like viologens to serve as…”
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    Biochemical Characterization of the Num1-Mdm36 Complex at the Mitochondria-Plasma Membrane Contact Site by Won, Jongdae, Choi, Yuri, Yun, Yaejin, Lee, Hyung Ho

    Published in Molecules and cells (2021)
    “…In eukaryotic cells, organelles are distributed and positioned in proximity to each other through molecular tether proteins. Among these, the…”
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    Dissecting the structural features of β-arrestins as multifunctional proteins by Yun, Yaejin, Ji, Jeongseok, Lee, Hyung Ho

    “…β-arrestins bind active G protein-coupled receptors (GPCRs) and play a crucial role in receptor desensitization and internalization. The classical paradigm of…”
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  7. 7

    GPCR targeting of E3 ubiquitin ligase MDM2 by inactive β-arrestin by Yun, Yaejin, Yoon, Hye-Jin, Jeong, Yejin, Choi, Yuri, Jang, Soonmin, Chung, Ka Young, Lee, Hyung Ho

    “…E3 ubiquitin ligase Mdm2 facilitates β-arrestin ubiquitination, leading to the internalization of G protein-coupled receptors (GPCRs). In this process,…”
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  8. 8

    Reversible Protein Conjugation on Live Cell Surfaces by Specific Recognition between Coiled-Coil Motifs of Natural Amino Acid Sequences by Ahn, Joon Hyung, Kang, Sunah, Park, Sohyun, Song, Hojoon, Yun, Yaejin, Choi, Sejong, Chong, Seung-Eun, Cheon, Dae Hee, Chun, Dahyun, Oh, Jae Hoon, Nam, Sohee, Lee, Yan

    Published in Biomacromolecules (14-09-2020)
    “…In this study, we propose a reversible covalent conjugation method for peptides, proteins, and even live cells based on specific recognition between natural…”
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    Journal Article