Search Results - "Yun, M.R."

Co-clinical trials demonstrate predictive biomarkers for dovitinib, an FGFR inhibitor, in lung squamous cell carcinoma by Kim, H.R., Kang, H.N., Shim, H.S., Kim, E.Y., Kim, J., Kim, D.J., Lee, J.G., Lee, C.Y., Hong, M.H., Kim, S.-M., Kim, H., Pyo, K.-H., Yun, M.R., Park, H.J., Han, J.Y., Youn, H.A., Ahn, M.-J., Paik, S., Kim, T.-M., Cho, B.C.

“…We conducted co-clinical trials in patient-derived xenograft (PDX) models to identify predictive biomarkers for the multikinase inhibitor dovitinib in lung…”
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999P JIN-A02, a fourth-generation, highly effective tyrosine kinase inhibitor with intracranial activity, targeting EGFR C797S mutations in NSCLC by Yun, M.R., Yu, M.R., Duggirala, K.B., Lee, K., Lim, S.M., Jo, A., Seah, E., Kim, C., Cho, B.C.

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1174P The MET inhibitor ABN401 in combination with the third-generation EGFR-TKI is effective MET-amplified and EGFR-mutant NSCLC with acquired resistance to third-generation EGFR-TKI in preclinical models by Yu, M.R., Yun, M.R., Lee, S., Rajasekaran, N., Park, K.E., Kim, N.Y., Hong, S., Oh, S.Y., Lee, Y.W., Lee, E.J., Kim, C.G., Lim, S.M., Choi, J., Cho, B.C.

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Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK by Lee, Y-h, Yun, M R, Kim, H M, Jeon, B H, Park, B-C, Lee, B-W, Kang, E S, Lee, H C, Park, Y W, Cha, B-S

“…Background/Objectives: Activation of Notch signaling pathologically enhances lipogenesis and gluconeogenesis in the liver causing non-alcoholic fatty liver…”
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MS444 5-LIPOXYGENASE-DERIVED LEUKOTRIENE B4 MEDIATES HNE-ENHANCED ROS PRODUCTION IN MURINE MACROPHAGES VIA ACTIVATION OF NADPH OXIDASE by Kim, C.D., Yun, M.R., Park, H.M., Seo, K.W., Lee, S.J., Park, S.Y., Bae, S.S.

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MS444 5-LIPOXYGENASE-DERIVED LEUKOTRIENE B 4 MEDIATES HNE-ENHANCED ROS PRODUCTION IN MURINE MACROPHAGES VIA ACTIVATION OF NADPH OXIDASE by Kim, C.D., Yun, M.R., Park, H.M., Seo, K.W., Lee, S.J., Park, S.Y., Bae, S.S.

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