Search Results - "Yun, Hyeong Rok"

Evogliptin, a DPP-4 inhibitor, prevents diabetic cardiomyopathy by alleviating cardiac lipotoxicity in db/db mice by Pham, Trong Kha, Nguyen, To Hoai T., Yi, Joo Mi, Kim, Gwang Sil, Yun, Hyeong Rok, Kim, Hyoung Kyu, Won, Jong Chul

“…Dipeptidyl peptidase-4 (DPP-4) inhibitors are glucose-lowering drugs for type 2 diabetes mellitus (T2DM). We investigated whether evogliptin® (EVO), a DPP-4…”
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Roles of Autophagy in Oxidative Stress by Yun, Hyeong Rok, Jo, Yong Hwa, Kim, Jieun, Shin, Yoonhwa, Kim, Sung Soo, Choi, Tae Gyu

“…Autophagy is a catabolic process for unnecessary or dysfunctional cytoplasmic contents by lysosomal degradation pathways. Autophagy is implicated in various…”
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Effects of cisplatin on mitochondrial function and autophagy-related proteins in skeletal muscle of rats by Seo, Dae Yun, Bae, Jun Hyun, Zhang, Didi, Song, Wook, Kwak, Hyo-Bum, Heo, Jun-Won, Jung, Su-Jeen, Yun, Hyeong Rok, Kim, Tae Nyun, Lee, Sang Ho, Kim, Amy Hyein, Jeong, Dae Hoon, Kim, Hyoung Kyu, Han, Jin

“…Cisplatin is widely known as an anti-cancer drug. However, the effects of cisplatin on mitochondrial function and autophagy-related proteins levels in the…”
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Echinochrome A Treatment Alleviates Atopic Dermatitis-like Skin Lesions in NC/Nga Mice via IL-4 and IL-13 Suppression by Yun, Hyeong Rok, Ahn, Sang Woo, Seol, Bomin, Vasileva, Elena A, Mishchenko, Natalia P, Fedoreyev, Sergey A, Stonik, Valentin A, Han, Jin, Ko, Kyung Soo, Rhee, Byoung Doo, Seol, Jung Eun, Kim, Hyoung Kyu

“…Atopic dermatitis (AD) is a chronic inflammatory skin disease in which skin barrier dysfunction leads to dryness, pruritus, and erythematous lesions. AD is…”
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Echinochrome A Protects against Ultraviolet B-induced Photoaging by Lowering Collagen Degradation and Inflammatory Cell Infiltration in Hairless Mice by Seol, Jung Eun, Ahn, Sang Woo, Seol, Bomin, Yun, Hyeong Rok, Park, Nammi, Kim, Hyoung Kyu, Vasileva, Elena A, Mishchenko, Natalia P, Fedoreyev, Sergey A, Stonik, Valentin A, Han, Jin

“…Echinochrome A (Ech A, 7-ethyl-2,3,5,6,8-pentahydroxy-1,4-naphthoquinone) has been known to exhibit anti-oxidative and anti-inflammatory effects. However, no…”
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Echinochrome A Prevents Diabetic Nephropathy by Inhibiting the PKC-Iota Pathway and Enhancing Renal Mitochondrial Function in db/db Mice by Pham, Trong Kha, Nguyen, To Hoai T, Yun, Hyeong Rok, Vasileva, Elena A, Mishchenko, Natalia P, Fedoreyev, Sergey A, Stonik, Valentin A, Vu, Thu Thi, Nguyen, Huy Quang, Cho, Sung Woo, Kim, Hyoung Kyu, Han, Jin

“…Echinochrome A (EchA) is a natural bioproduct extracted from sea urchins, and is an active component of the clinical drug, Histochrome . EchA has antioxidant,…”
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Palmitoyl Protein Thioesterase 1 Is Essential for Myogenic Autophagy of C2C12 Skeletal Myoblast by Yun, Hyeong Rok, Jo, Yong Hwa, Kim, Jieun, Nguyen, Ngoc Ngo Yen, Shin, Yoonhwa, Kim, Sung Soo, Choi, Tae Gyu

“…Skeletal muscle differentiation is an essential process for the maintenance of muscle development and homeostasis. Reactive oxygen species (ROS) are critical…”
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Mitochondrial ROS-derived PTEN oxidation activates PI3K pathway for mTOR-induced myogenic autophagy by Kim, Jin-Hwan, Choi, Tae Gyu, Park, Seolhui, Yun, Hyeong Rok, Nguyen, Ngoc Ngo Yen, Jo, Yong Hwa, Jang, Miran, Kim, Jieun, Kim, Joungmok, Kang, Insug, Ha, Joohun, Murphy, Michael P., Tang, Dean G., Kim, Sung Soo

“…Muscle differentiation is a crucial process controlling muscle development and homeostasis. Mitochondrial reactive oxygen species (mtROS) rapidly increase and…”
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Cyclophilin B induces chemoresistance by degrading wild‐type p53 via interaction with MDM2 in colorectal cancer by Choi, Tae Gyu, Nguyen, Minh Nam, Kim, Jieun, Jo, Yong Hwa, Jang, Miran, Nguyen, Ngoc Ngo Yen, Yun, Hyeong Rok, Choe, Wonchae, Kang, Insug, Ha, Joohun, Tang, Dean G, Kim, Sung Soo

“…Colorectal cancer (CRC) is one of the leading causes of cancer‐related deaths worldwide. Chemoresistance is a major problem for effective therapy in CRC. Here,…”
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PAC-5 Gene Expression Signature for Predicting Prognosis of Patients with Pancreatic Adenocarcinoma by Kim, Jieun, Jo, Yong Hwa, Jang, Miran, Nguyen, Ngoc Ngo Yen, Yun, Hyeong Rok, Ko, Seok Hoon, Shin, Yoonhwa, Lee, Ju-Seog, Kang, Insug, Ha, Joohun, Choi, Tae Gyu, Kim, Sung Soo

“…Pancreatic adenocarcinoma (PAC) is one of the most aggressive malignancies. Intratumoural molecular heterogeneity impedes improvement of the overall survival…”
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Effects of cisplatin on mitochondrial function and autophagy-related proteins in skeletal muscle of rats by Seo, Dae Yun, Bae, Jun Hyun, Zhang, Didi, Song, Wook, Kwak, Hyo-Bum, Heo, Jun-Won, Jung, Su-Jeen, Yun, Hyeong Rok, Kim, Tae Nyun, Lee, Sang Ho, Kim, Amy Hyein, Jeong, Dae Hoon, Kim, Hyoung Kyu, Han, Jin

“…Cisplatin is widely known as an anti-cancer drug. However, the effects of cisplatin on mitochondrial function and autophagyrelated proteins levels in the…”
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An 8-gene signature for prediction of prognosis and chemoresponse in non-small cell lung cancer by Shahid, Muhammad, Choi, Tae Gyu, Nguyen, Minh Nam, Matondo, Abel, Jo, Yong Hwa, Yoo, Ji Youn, Nguyen, Ngoc Ngo Yen, Yun, Hyeong Rok, Kim, Jieun, Akter, Salima, Kang, Insug, Ha, Joohun, Maeng, Chi Hoon, Kim, Si-Young, Lee, Ju-Seog, Kim, Jayoung, Kim, Sung Soo

“…Identification of a potential gene signature for improved diagnosis in non-small cell lung cancer (NSCLC) patient is necessary. Here, we aim to establish and…”
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Prognostic value and their clinical implication of 89-gene signature in glioma by Shahid, Muhammad, Cho, Kyoung Min, Nguyen, Minh Nam, Choi, Tae Gyu, Jo, Yong Hwa, Aryal, Saurav Nath, Yoo, Ji Youn, Yun, Hyeong Rok, Lee, Jae Woong, Eun, Young Gyu, Lee, Ju-Seog, Kang, Insug, Ha, Joohun, Yoon, Hwi-Joong, Kim, Si-Young, Kim, Sung Soo

“…Gliomas are the most common and aggressive primary tumors in adults. The current approaches, such as histological classification and molecular genetics, have…”
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