Search Results - "Yumikura‐Futatsugi, Shizue"

A critical role of IL-33 in experimental allergic rhinitis by Haenuki, Yoko, MD, Matsushita, Kazufumi, PhD, Futatsugi-Yumikura, Shizue, BPharm, Ishii, Ken J., MD, PhD, Kawagoe, Tatsukata, MD, PhD, Imoto, Yoshimasa, MD, PhD, Fujieda, Shigeharu, MD, PhD, Yasuda, Makoto, MD, PhD, Hisa, Yasuo, MD, PhD, Akira, Shizuo, MD, PhD, Nakanishi, Kenji, MD, PhD, Yoshimoto, Tomohiro, MD, PhD

“…Background We reported previously that serum levels of IL-33 are significantly increased in patients with allergic rhinitis (AR). However, very little is known…”
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Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system by Kondo, Yuichi, Yoshimoto, Tomohiro, Yasuda, Koubun, Futatsugi-Yumikura, Shizue, Morimoto, Mai, Hayashi, Nobuki, Hoshino, Tomoaki, Fujimoto, Jiro, Nakanishi, Kenji

“…Systemic administration of IL-18 induces polyclonal IgE responses by causing NKT cells to express CD40 ligand and to produce IL-4. Administration of IL-33 also…”
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Contribution of IL-33 to induction and augmentation of experimental allergic conjunctivitis by Matsuba-Kitamura, Saori, Yoshimoto, Tomohiro, Yasuda, Koubun, Futatsugi-Yumikura, Shizue, Taki, Yuuko, Muto, Taichiro, Ikeda, Tomohiro, Mimura, Osamu, Nakanishi, Kenji

“…IL-33, a member of the IL-1 family of cytokines, is the ligand for ST2 (IL-33Rα chain). IL-33 has the capacity to induce Th2 cytokine production from Th2…”
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Immediate-type contact hypersensitivity is reduced in interleukin-33 knockout mice by Imai, Yasutomo, Yasuda, Koubun, Sakaguchi, Yoshiko, Futatsugi-Yumikura, Shizue, Yoshimoto, Tomohiro, Nakanishi, Kenji, Yamanishi, Kiyofumi

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YKL-40 (chitinase 3-like-1) as a biomarker for psoriasis vulgaris and pustular psoriasis by Imai, Yasutomo, Tsuda, Tatsuya, Aochi, Seiko, Futatsugi-Yumikura, Shizue, Sakaguchi, Yoshiko, Nakagawa, Noboru, Iwatsuki, Keiji, Yamanishi, Kiyofumi

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Contribution of IL-33–activated type II innate lymphoid cells to pulmonary eosinophilia in intestinal nematode-infected mice by Yasuda, Koubun, Muto, Taichiro, Kawagoe, Tatsukata, Matsumoto, Makoto, Sasaki, Yuki, Matsushita, Kazufumi, Taki, Yuko, Futatsugi-Yumikura, Shizue, Tsutsui, Hiroko, Ishii, Ken J, Yoshimoto, Tomohiro, Akira, Shizuo, Nakanishi, Kenji

“…When animals are infected with helminthic parasites, resistant hosts show type II helper T immune responses to expel worms. Recently, natural helper (NH) cells…”
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Crucial role of impaired Kupffer cell phagocytosis on the decreased Sonazoid-enhanced echogenicity in a liver of a nonalchoholic steatohepatitis rat model by Yoshikawa, Shohei, Iijima, Hiroko, Saito, Masaki, Tanaka, Hironori, Imanishi, Hiroyasu, Yoshimoto, Naoki, Yoshimoto, Tomohiro, Futatsugi-Yumikura, Shizue, Nakanishi, Kenji, Tsujimura, Tohru, Nishigami, Takashi, Kudo, Atsushi, Arii, Shigeki, Nishiguchi, Shuhei

“…Aims:  To evaluate the dynamics of Kupffer cell (KC) phagocytosis by performing both in vivo and in vitro studies using Sonazoid (GE Healthcare, Oslo) in a rat…”
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Contribution of IL-18 to eosinophilic airway inflammation induced by immunization and challenge with Staphylococcus aureus proteins by Kuroda-Morimoto, Mai, Tanaka, Hidehisa, Hayashi, Nobuki, Nakahira, Masakiyo, Imai, Yasutomo, Imamura, Michiko, Yasuda, Koubun, Yumikura-Futatsugi, Shizue, Matsui, Kiyoshi, Nakashima, Toshihiro, Sugimura, Kazuhisa, Tsutsui, Hiroko, Sano, Hajime, Nakanishi, Kenji

“…We previously reported that intranasal challenge with ovalbumin (OVA) plus IL-18 induces airway hyperresponsiveness (AHR) and eosinophilic airway inflammation…”
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Persistent secretion of IL‐18 in the skin contributes to IgE response in mice by Nakano, Hiroki, Tsutsui, Hiroko, Terada, Makoto, Yasuda, Koubun, Matsui, Kiyoshi, Yumikura‐Futatsugi, Shizue, Yamanaka, Kei‐ichi, Mizutani, Hitoshi, Yamamura, Takehira, Nakanishi, Kenji

“…After exposure of the skin to microbes, the host develops skin‐specific inflammation and an acquired immune response, in which keratinocytes (KC) and…”
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Identification of a novel type 2 innate immunocyte with the ability to enhance IgE production by Fukuoka, Ayumi, Futatsugi-Yumikura, Shizue, Takahashi, Suzuka, Kazama, Hirotaka, Iyoda, Tomonori, Yoshimoto, Tomohiro, Inaba, Kayo, Nakanishi, Kenji, Yonehara, Shin

“…Fas (CD95), a member of the tumor necrosis factor receptor superfamily, mediates apoptosis-inducing signals in its expressing cells, especially in…”
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IL-18 Contributes to the Spontaneous Development of Atopic Dermatitis-like Inflammatory Skin Lesion Independently of IgE/Stat6 under Specific Pathogen-Free Conditions by Konishi, Hiroshi, Tsutsui, Hiroko, Murakami, Takaaki, Yumikura-Futatsugi, Shizue, Yamanaka, Kei-ichi, Tanaka, Minoru, Iwakura, Yohichiro, Suzuki, Noboru, Takeda, Kiyoshi, Akira, Shizuo, Nakanishi, Kenji, Mizutani, Hitoshi

“…Atopic dermatitis (AD) is a pruritic inflammatory skin disease. Because IL-18 directly stimulates T cells and mast cells to release AD-associated molecules,…”
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Pathogenic Th2-type follicular helper T cells contribute to the development of lupus in Fas-deficient mice by Futatsugi-Yumikura, Shizue, Matsushita, Kazufumi, Fukuoka, Ayumi, Takahashi, Suzuka, Yamamoto, Nayu, Yonehara, Shin, Nakanishi, Kenji, Yoshimoto, Tomohiro

“…Pathogenic Th2-type Tfh cells contribute to diseases associated with Fas deficiency Fas mutant mice are well recognized as autoimmune mouse models, which…”
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Fas deficiency in mice with the Balb/c background induces blepharitis with allergic inflammation and hyper-IgE production in conjunction with severe autoimmune disease by Takahashi, Suzuka, Futatsugi-Yumikura, Shizue, Fukuoka, Ayumi, Yoshimoto, Tomohiro, Nakanishi, Kenji, Yonehara, Shin

“…Fas (CD95) is a cell surface death receptor belonging to the tumor necrosis factor receptor superfamily, which mediates apoptosis-inducing signaling when…”
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A regulatory role for suppressor of cytokine signaling‐1 in Th polarization in vivo by Fujimoto, Minoru, Tsutsui, Hiroko, Yumikura‐Futatsugi, Shizue, Ueda, Haruyasu, Xingshou, Ouyang, Abe, Tatsuo, Kawase, Ichiro, Nakanishi, Kenji, Kishimoto, Tadamitsu, Naka, Tetsuji

“…Suppressor of cytokine signaling (SOCS)‐1 is an inhibitory molecule for JAK, and its deficiency in mice leads to lymphocyte‐dependent multi‐organ disease and…”
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Contribution of TIR domain-containing adapter inducing IFN-β-mediated IL-18 release to LPS-induced liver injury in mice by Imamura, Michiko, Tsutsui, Hiroko, Yasuda, Koubun, Uchiyama, Ryosuke, Yumikura-Futatsugi, Shizue, Mitani, Keiko, Hayashi, Shuhei, Akira, Shizuo, Taniguchi, Shun-ichiro, Rooijen, Nico Van, Tschopp, Jurg, Yamamoto, Tetsuya, Fujimoto, Jiro, Nakanishi, Kenji

“…Background/Aims After treatment with heat-killed Propionibacterium acnes mice show dense hepatic granuloma formation. Such mice develop liver injury in an…”
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Critical Roles of Myeloid Differentiation Factor 88-Dependent Proinflammatory Cytokine Release in Early Phase Clearance of Listeria monocytogenes in Mice by Seki, Ekihiro, Tsutsui, Hiroko, Tsuji, Noriko M, Hayashi, Nobuki, Adachi, Keishi, Nakano, Hiroki, Futatsugi-Yumikura, Shizue, Takeuchi, Osamu, Hoshino, Katsuaki, Akira, Shizuo, Fujimoto, Jiro, Nakanishi, Kenji

“…Listeria monocytogenes (LM), a facultative intracellular Gram-positive bacterium, often causes lethal infection of the host. In this study we investigated the…”
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Pathogenic T sub(h)2-type follicular helper T cells contribute to the development of lupus in Fas-deficient mice by Futatsugi-Yumikura, Shizue, Matsushita, Kazufumi, Fukuoka, Ayumi, Takahashi, Suzuka, Yamamoto, Nayu, Yonehara, Shin, Nakanishi, Kenji, Yoshimoto, Tomohiro

“…Pathogenic Th sub(2)-type T sub(fh) cells contribute to diseases associated with Fas deficiency Pathogenic Th sub(2)-type T sub(fh) cells contribute to…”
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Balb/c FasKO mice develop allergic blepharitis associated with hyper-production of IgE by Fukuoka, Ayumi, Yumikura-Futatsugi, Shizue, Takahashi, Suzuka, Kazama, Hirotaka, Nakanishi, Kenji, Yonehara, Shin

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A regulatory role for suppressor of cytokine signaling-1 in T(h) polarization in vivo by Fujimoto, Minoru, Tsutsui, Hiroko, Yumikura-Futatsugi, Shizue, Ueda, Haruyasu, Xingshou, Ouyang, Abe, Tatsuo, Kawase, Ichiro, Nakanishi, Kenji, Kishimoto, Tadamitsu, Naka, Tetsuji

“…Suppressor of cytokine signaling (SOCS)-1 is an inhibitory molecule for JAK, and its deficiency in mice leads to lymphocyte-dependent multi-organ disease and…”
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A regulatory role for suppressor of cytokine signaling-1 in T sub(h) polarization in vivo by Fujimoto, Minoru, Tsutsui, Hiroko, Yumikura-Futatsugi, Shizue, Ueda, Haruyasu, Xingshou, Ouyang, Abe, Tatsuo, Kawase, Ichiro, Nakanishi, Kenji, Kishimoto, Tadamitsu, Naka, Tetsuji

“…Suppressor of cytokine signaling (SOCS)-1 is an inhibitory molecule for JAK, and its deficiency in mice leads to lymphocyte-dependent multi-organ disease and…”
Get full text