Search Results - "Yuimi Koyama"
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Novel Keap1-Nrf2 Protein-Protein Interaction Inhibitor UBE-1099 Ameliorates Progressive Phenotype in Alport Syndrome Mouse Model
Published in Kidney360 (28-04-2022)“…Background Bardoxolone methyl activates nuclear factor erythroid 2–related factor 2 (Nrf2) via covalent binding and irreversible inhibition of Kelch-like…”
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Efficacy of Keap1-Nrf2 protein-protein interaction inhibitor for progressive phenotype in Alport syndrome mouse model
Published in Japanese Journal of Pediatric Nephrology (15-11-2022)Get full text
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Trimerization profile of type IV collagen COL4A5 exon deletion in X-linked Alport syndrome
Published in Clinical and experimental nephrology (01-09-2024)“…Background Alport syndrome (AS) is a genetic kidney disease caused by a mutation in type IV collagen α3, α4, and α5, which are normally secreted as…”
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CyclosporinA Derivative as Therapeutic Candidate for Alport Syndrome by Inducing Mutant Type IV Collagen Secretion
Published in Kidney360 (01-07-2023)“…Background Type IV collagen α3,4,5 (α345(IV)) is an obligate trimer that is secreted to form a collagen network, which is the structural foundation of basement…”
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