Search Results - "Yuill, Elizabeth M"

Electrochemical Aspects of Mass Spectrometry: Atmospheric Pressure Ionization and Ambient Ionization for Bioanalysis by Yuill, Elizabeth M., Baker, Lane A.

“…This MiniReview details the evolution and present state of combined electrochemical (EC) and atmospheric pressure sampling/ionization mass spectrometric (MS)…”
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Mechanistic studies to understand peak tailing due to sulfinic acid- and carboxylic acid-silanophilic interactions in reversed-phase liquid chromatography by Zhou, Yiyang, Ramirez, Antonio, Yuill, Elizabeth M., Wang, Qinggang

“…•Peak tailing of sulfinic acids and carboxylic acids investigated in acidic MP RPLC.•The neutral protonated form of the acids was found responsible for peak…”
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Circumventing glass vial and diluent effects on solution stability of small molecule analytes during analytical method development and validation by Huang, Yande, Hu, Yue, Yuill, Elizabeth M., Marriott, Andrew S., Chadwick, James, Li, Jieming, Zang, Jia, Miller, Scott A.

“…Solution stability of analytes plays an important part in qualitative analysis, especially in conducting accurate, quantitative analyses. Sample diluents and…”
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Electrospray Ionization from Nanopipette Emitters with Tip Diameters of Less than 100 nm by Yuill, Elizabeth M, Sa, Niya, Ray, Steven J, Hieftje, Gary M, Baker, Lane A

“…Work presented here demonstrates application of nanopipettes pulled to orifice diameters of less than 100 nm as electrospray ionization emitters for mass…”
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Ion concentration in micro and nanoscale electrospray emitters by Yuill, Elizabeth M., Baker, Lane A.

“…Solution-phase ion transport during electrospray has been characterized for nanopipettes, or glass capillaries pulled to nanoscale tip dimensions, and…”
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Leveraging AQbD Principles for Development of Challenging Drug Substance Stability-Indicating Methods by Yuill, Elizabeth M, Ileka, Kevin M, La Cruz, Thomas E, Li, Jieming, Shackman, Jonathan G, Tattersall, Peter I, Zang, Jia

“…Drug substance stability-indicating methods (SIMs) must undergo a litany of optimization and robustness stresses to ensure that the methods can be successfully…”
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Scanning Electrospray Microscopy with Nanopipets by Yuill, Elizabeth M, Shi, Wenqing, Poehlman, John, Baker, Lane A

“…Electrospray from nanopipets is used to realize scanning electrospray microscopy (SESM). This technique provides an ambient, noncontact method to investigate…”
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Probe-Substrate Distance Control in Desorption Electrospray Ionization by Yarger, Tyler J., Yuill, Elizabeth M., Baker, Lane A.

“…We introduce probe-substrate distance (D ps )-control to desorption electrospray ionization (DESI) and report a systematic investigation of key experimental…”
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Inside Back Cover: Electrochemical Aspects of Mass Spectrometry: Atmospheric Pressure Ionization and Ambient Ionization for Bioanalysis (ChemElectroChem 4/2017) by Yuill, Elizabeth M., Baker, Lane A.

“…The Inside Back Cover picture highlights how interesting opportunities for new analytical and physical measurements can arise through the combination (or…”
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Tracking the Isotopologues: Process Improvement for the Synthesis of a Deuterated Pyrazole by Garlets, Zachary J., Yuill, Elizabeth M., Yang, Alice, Ye, Qingmei, Ding, Wei, Wood, Christopher, Fan, Junying, Cuniere, Nicolas Lucien, Sfouggatakis, Chris

“…The use of deuterium in the pharmaceutical industry has expanded in recent years as medicinal chemists seek to design compounds with improved and favorable…”
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An azirine solid-state photodegradant of the CCR2/CCR5 dual antagonist BMS-813160 by Ayers, Sloan, La Cruz, Thomas, Park, Hyunsoo, Ramirez, Antonio, Hritzko, Benjamin, Sarjeant, Amy, Lin, Ziqing, Zaretsky, Serge, Huang, Yande, Zang, Jia, Yuill, Elizabeth M., Fenster, Michaël D.B.

“…[Display omitted] The synthesis of the CCR2/5 dual chemokine antagonist BMS-813160 (1) presented a number of interesting impurity and degradant structure…”
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Electrospray from Nanopipettes: Fundamentals and Applications by Yuill, Elizabeth M

“…Nanopipettes, or pulled glass capillaries with inner diameters that range from tens to hundreds of nanometers, have been recently developed and characterized…”
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