Search Results - "Yuichi Hiyama"

Pexidartinib and Immune Checkpoint Inhibitors Combine to Activate Tumor Immunity in a Murine Colorectal Cancer Model by Depleting M2 Macrophages Differentiated by Cancer-Associated Fibroblasts by Shimizu, Daisuke, Yuge, Ryo, Kitadai, Yuki, Ariyoshi, Misa, Miyamoto, Ryo, Hiyama, Yuichi, Takigawa, Hidehiko, Urabe, Yuji, Oka, Shiro

“…Tumor-associated macrophages (TAMs) and cancer-associated fibroblasts (CAFs) are known to play supportive roles in tumor development and progression, but their…”
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Anti-tumor necrosis factor-alpha monoclonal antibody suppresses colorectal cancer growth in an orthotopic transplant mouse model by Takasago, Takeshi, Hayashi, Ryohei, Ueno, Yoshitaka, Ariyoshi, Misa, Onishi, Kana, Yamashita, Ken, Hiyama, Yuichi, Takigawa, Hidehiko, Yuge, Ryo, Urabe, Yuji, Oka, Shiro, Kitadai, Yasuhiko, Tanaka, Shinji

“…The risk of malignant tumor progression has been a concern associated with the use of anti-tumor necrosis factor-alpha monoclonal antibody (anti-TNFα mAb). On…”
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Characteristics and Treatment Outcomes of Small-bowel Angioectasia in Systemic Sclerosis Patients: A Retrospective Observational Study by Iio, Sumio, Oka, Shiro, Sumioka, Akihiko, Tsuboi, Akiyoshi, Tanaka, Hidenori, Yamashita, Ken, Hiyama, Yuichi, Kotachi, Takahiro, Takigawa, Hidehiko, Hayashi, Ryohei, Yuge, Ryo, Urabe, Yuji, Tanaka, Shinji

“…Objective Systemic sclerosis (SSc) is defined as an autoimmune disease presenting with fibrosis of various organs and vascular endothelial damage. Vascular…”
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Predictive factors of portal hypertensive enteropathy exacerbations based on long-term outcomes by Matsubara, Yuka, Tsuboi, Akiyoshi, Hirata, Issei, Sumioka, Akihiko, Takasago, Takeshi, Tanaka, Hidenori, Yamashita, Ken, Hiyama, Yuichi, Takigawa, Hidehiko, Murakami, Eisuke, Tsuge, Masataka, Urabe, Yuji, Oka, Shiro

“…Portal hypertensive enteropathy (PHE) is a small-bowel lesion observed in patients with portal hypertension. The clinical significance of endoscopic findings…”
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Long-term prognosis after endoscopic submucosal dissection for esophageal cancer in older adult patients by Konishi, Hirona, Urabe, Yuji, Nakamura, Takeo, Ishibashi, Kazuki, Mizuno, Junichi, Fukuhara, Motomitsu, Takasago, Takeshi, Tanaka, Hidenori, Tsuboi, Akiyoshi, Yamashita, Ken, Hiyama, Yuichi, Takigawa, Hidehiko, Kotachi, Takahiro, Yuge, Ryo, Ishikawa, Akira, Oka, Shiro

“…The validity of endoscopic submucosal dissection (ESD) for esophageal squamous cell carcinoma (ESCC) in older individuals with comorbidities remains unclear…”
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Predictive factors for esophageal stenosis in patients receiving prophylactic steroid therapy after endoscopic submucosal dissection for esophageal squamous cell carcinoma by Mizuno, Junichi, Urabe, Yuji, Oka, Shiro, Konishi, Hirona, Ishibashi, Kazuki, Fukuhara, Motomitsu, Tanaka, Hidenori, Tsuboi, Akiyoshi, Yamashita, Ken, Hiyama, Yuichi, Kotachi, Takahiro, Takigawa, Hidehiko, Yuge, Ryo, Hiyama, Toru, Tanaka, Shinji

“…Methods to prevent esophageal stenosis (ES) after endoscopic submucosal dissection (ESD) for superficial esophageal squamous cell carcinoma (ESCC) have…”
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Diagnostic Yield of Colon Capsule Endoscopy in Detection of Superficial Colorectal Lesions by Otani, Ichiro, Oka, Shiro, Tanaka, Shinji, Iio, Sumio, Tsuboi, Akiyoshi, Kunihara, Sayoko, Hiyama, Yuichi, Chayama, Kazuaki

“…The efficacy of second-generation PillCam -COLON2 capsule endoscopy (CCE2) in detecting colorectal superficial lesions remains unclear. We sought to determine…”
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Diagnostic yield of proximal jejunal lesions with third‐generation capsule endoscopy by Hirata, Issei, Tsuboi, Akiyoshi, Oka, Shiro, Sumioka, Akihiko, Iio, Sumio, Hiyama, Yuichi, Kotachi, Takahiro, Yuge, Ryo, Hayashi, Ryohei, Urabe, Yuji, Tanaka, Shinji

“…Objectives Capsule endoscopy (CE) has been shown to have poor diagnostic performance when the capsule passes quickly through the small bowel, especially the…”
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Potential of Helicobacter pylori‐uninfected signet ring cell carcinoma to invade the submucosal layer by Yorita, Naoki, Ito, Masanori, Boda, Tomoyuki, Kotachi, Takahiro, Nagasaki, Naoko, Abuduwaili, Madina, Hata, Kosaku, Hiyama, Yuichi, Oka, Shiro, Yoshihara, Masaharu, Kitadai, Yasuhiko, Tanaka, Shinji, Chayama, Kazuaki

“…Background and Aim The typical histology of Helicobacter pylori‐uninfected gastric cancer is signet ring cell carcinoma (SRCC) localized in the mucosal layer,…”
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Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice by Tsushima, Ken, Tsuge, Masataka, Hiraga, Nobuhiko, Uchida, Takuro, Murakami, Eisuke, Makokha, Grace Naswa, Kurihara, Mio, Nomura, Motonobu, Hiyama, Yuichi, Fujino, Hatsue, Ono, Atsushi, Nakahara, Takashi, Yamauchi, Masami, Abe-Chayama, Hiromi, Kawaoka, Tomokazu, Miki, Daiki, Imamura, Michio, Aikata, Hiroshi, Hayes, Clair Nelson, Chayama, Kazuaki

“…Background and aims The clinical course and responsiveness to antiviral treatments differs among hepatitis B virus (HBV) genotypes. However, the cause of these…”
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The Anti-Tumor Effect of the Newly Developed LAT1 Inhibitor JPH203 in Colorectal Carcinoma, According to a Comprehensive Analysis by Otani, Rina, Takigawa, Hidehiko, Yuge, Ryo, Shimizu, Daisuke, Ariyoshi, Misa, Miyamoto, Ryo, Kadota, Hiroki, Hiyama, Yuichi, Hayashi, Ryohei, Urabe, Yuji, Ishikawa, Akira, Oue, Naohide, Kitadai, Yasuhiko, Oka, Shiro, Tanaka, Shinji

“…A novel large neutral amino acid transporter 1 (LAT1)-specific inhibitor, JPH203, is expected to cause cancer-specific starvation and possess anti-tumor…”
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The Evaluation of Esophageal Motility Using Infusion Manometry with a Trans-nasal Endoscope: A Preliminary Study by Hata, Kosaku, Ito, Masanori, Boda, Tomoyuki, Kotachi, Takahiro, Kiso, Mariko, Hiyama, Yuichi, Kuroki, Kazutaka, Yorita, Naoki, Nagasaki, Naoko, Abduwaili, Madina, Tanaka, Shinji, Chayama, Kazuaki

“…Objective The Chicago classification using high-resolution manometry (HRM) has been proposed for the diagnosis of esophageal motility disorders. However, HRM…”
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Comprehensive Analysis of Gene Expression Profiling to Explore Predictive Markers for Eradication Therapy Efficacy against Helicobacter pylori -Negative Gastric MALT Lymphoma by Takigawa, Hidehiko, Yuge, Ryo, Miyamoto, Ryo, Otani, Rina, Kadota, Hiroki, Hiyama, Yuichi, Hayashi, Ryohei, Urabe, Yuji, Sentani, Kazuhiro, Oue, Naohide, Kitadai, Yasuhiko, Oka, Shiro, Tanaka, Shinji

“…Although radiotherapy is the standard treatment for (Hp)-negative gastric mucosa-associated lymphoid tissue (MALT) lymphoma, eradication therapy using…”
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Outcomes of endoscopic submucosal dissection in patients who develop metachronous superficial esophageal squamous cell carcinoma close to a post-endoscopic submucosal dissection scar by Fukuhara, Motomitsu, Urabe, Yuji, Oka, Shiro, Mizuno, Jyunichi, Tanaka, Hidenori, Yamashita, Ken, Hiyama, Yuichi, Takigawa, Hidehiko, Kotachi, Takahiro, Yuge, Ryo, Arihiro, Koji, Tanaka, Shinji

“…Background The presence of post-endoscopic submucosal dissection (ESD) scars renders complete metachronous superficial esophageal squamous cell carcinoma…”
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Clinicopathological and genomic features of superficial esophageal squamous cell carcinomas in nondrinker, nonsmoker females by Fukuhara, Motomitsu, Urabe, Yuji, Nakahara, Hikaru, Ishikawa, Akira, Ishibashi, Kazuki, Konishi, Hirona, Mizuno, Junichi, Tanaka, Hidenori, Tsuboi, Akiyoshi, Yamashita, Ken, Hiyama, Yuichi, Takigawa, Hidehiko, Kotachi, Takahiro, Yuge, Ryo, Hayes, C. Nelson, Oka, Shiro

“…Background Esophageal squamous cell carcinoma (ESCC) is sometimes detected in non‐drinker and non‐smoker females who are considered to have very low risk of…”
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Endoscopic findings suggestive of a high risk of non-radical cure after definitive chemoradiotherapy for cT1bN0M0 esophageal squamous cell carcinoma by Fukuhara, Motomitsu, Urabe, Yuji, Oka, Shiro, Ishibashi, Kazuki, Konishi, Hirona, Mizuno, Junichi, Tanaka, Hidenori, Tsuboi, Akiyoshi, Yamashita, Ken, Hiyama, Yuichi, Takigawa, Hidehiko, Kotachi, Takahiro, Yuge, Ryo, Hayashi, Ryohei, Nishibuchi, Ikuno, Murakami, Yuji, Nagata, Yasushi, Tanaka, Shinji

“…Background Definitive chemoradiotherapy (DCRT) is a curative treatment option for cT1bN0M0 esophageal squamous cell carcinoma (ESCC); however, local residual…”
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Clinical usefulness of combination therapy with polidocanol injection and argon plasma coagulation for gastric antral vascular ectasia by Tamari, Hirosato, Oka, Shiro, Tanaka, Shinji, Hiyama, Yuichi, Ninomiya, Yuki, Kotachi, Takahiro, Boda, Tomoyuki, Yuge, Ryo, Urabe, Yuji, Kitadai, Yasuhiko, Chayama, Kazuaki

“…Background and Aim Gastric antral vascular ectasia (GAVE) causes gastrointestinal bleeding. The initial treatment for GAVE bleeding is endoscopic hemostasis,…”
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LONG-TERM PROGNOSIS AFTER ENDOSCOPIC SUBMUCOSAL DISSECTION FOR ESOPHAGEAL CANCER IN PATIENTS AGED OVER 65 YEARS by Konishi, Hirona, Urabe, Yuji, Nakamura, Takeo, Ishibashi, Kazuki, Mizuno, Junichi, Fukuhara, Motomitsu, Tanaka, Hidenori, Tsuboi, Akiyoshi, Yamashita, Ken, Hiyama, Yuichi, Takigawa, Hidehiko, Oka, Shiro

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LONG-TERM PROGNOSIS AFTER ENDOSCOPIC SUBMUCOSAL DISSECTION FOR ESOPHAGEAL CANCER IN PATIENTS AGED OVER 65 YEARS by Konishi, Hirona, Urabe, Yuji, Nakamura, Takeo, Ishibashi, Kazuki, Mizuno, Junichi, Fukuhara, Motomitsu, Tanaka, Hidenori, Tsuboi, Akiyoshi, Yamashita, Ken, Hiyama, Yuichi, Takigawa, Hidehiko, Oka, Shiro

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EP60 CLINICOPATHOLOGICAL FEATURES AND GENOMIC CHARACTERIZATION OF SUPERFICIAL ESOPHAGEAL SQUAMOUS CELL CARCINOMA IN NON DRINKER, NON SMOKER FEMALES by Fukuhara, Motomitsu, Urabe, Yuji, Oka, Shiro, Nakahara, Hikaru, Ishibashi, Kazuki, Konishi, Hirona, Mizuno, Junichi, Hiyama, Yuichi, Ishikawa, Akira, Hayes, C.N., Oue, Naohide, Tanaka, Shinji

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