Search Results - "Yui, Naofumi"

Ser-261 phospho-regulation is involved in pS256 and pS269-mediated aquaporin-2 apical translocation by Yui, Naofumi, Ando, Fumiaki, Sasaki, Sei, Uchida, Shinichi

“…Vasopressin catalyzes aquaporin-2 phosphorylation at several serine sites in the C-terminal region. Compared with Ser-256 and Ser-269 phosphorylation, the role…”
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Noncanonical Control of Vasopressin Receptor Type 2 Signaling by Retromer and Arrestin by Feinstein, Timothy N., Yui, Naofumi, Webber, Matthew J., Wehbi, Vanessa L., Stevenson, Hilary P., King, J. Darwin, Hallows, Kenneth R., Brown, Dennis, Bouley, Richard, Vilardaga, Jean-Pierre

“…The vasopressin type 2 receptor (V2R) is a critical G protein-coupled receptor (GPCR) for vertebrate physiology, including the balance of water and sodium…”
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Wnt5a induces renal AQP2 expression by activating calcineurin signalling pathway by Ando, Fumiaki, Sohara, Eisei, Morimoto, Tetsuji, Yui, Naofumi, Nomura, Naohiro, Kikuchi, Eriko, Takahashi, Daiei, Mori, Takayasu, Vandewalle, Alain, Rai, Tatemitsu, Sasaki, Sei, Kondo, Yoshiaki, Uchida, Shinichi

“…Heritable nephrogenic diabetes insipidus (NDI) is characterized by defective urine concentration mechanisms in the kidney, which are mainly caused by…”
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AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus by Ando, Fumiaki, Mori, Shuichi, Yui, Naofumi, Morimoto, Tetsuji, Nomura, Naohiro, Sohara, Eisei, Rai, Tatemitsu, Sasaki, Sei, Kondo, Yoshiaki, Kagechika, Hiroyuki, Uchida, Shinichi

“…Congenital nephrogenic diabetes insipidus (NDI) is characterized by the inability of the kidney to concentrate urine. Congenital NDI is mainly caused by…”
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The proteasome inhibitor bortezomib attenuates renal fibrosis in mice via the suppression of TGF-β1 by Zeniya, Moko, Mori, Takayasu, Yui, Naofumi, Nomura, Naohiro, Mandai, Shintaro, Isobe, Kiyoshi, Chiga, Motoko, Sohara, Eisei, Rai, Tatemitsu, Uchida, Shinichi

“…Kidney fibrosis and fibrogenesis significantly exacerbate chronic kidney disease (CKD) progression and are essential therapeutic targets. Bortezomib (BZM) is a…”
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LRBA is essential for urinary concentration and body water homeostasis by Hara, Yu, Ando, Fumiaki, Oikawa, Daisuke, Ichimura, Koichiro, Yanagawa, Hideki, Sakamaki, Yuriko, Nanamatsu, Azuma, Fujiki, Tamami, Mori, Shuichi, Suzuki, Soichiro, Yui, Naofumi, Mandai, Shintaro, Susa, Koichiro, Mori, Takayasu, Sohara, Eisei, Rai, Tatemitsu, Takahashi, Mikiko, Sasaki, Sei, Kagechika, Hiroyuki, Tokunaga, Fuminori, Uchida, Shinichi

“…Protein kinase A (PKA) directly phosphorylates aquaporin-2 (AQP2) water channels in renal collecting ducts to reabsorb water from urine for the maintenance of…”
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Ezrin directly interacts with AQP2 and promotes its endocytosis by Li, Wei, Jin, William W, Tsuji, Kenji, Chen, Ying, Nomura, Naohiro, Su, Limin, Yui, Naofumi, Arthur, Julian, Cotecchia, Susanna, Paunescu, Teodor G, Brown, Dennis, Lu, Hua A J

“…The water channel aquaporin-2 (AQP2) is a major regulator of water homeostasis in response to vasopressin (VP). Dynamic trafficking of AQP2 relies on its close…”
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Basolateral targeting and microtubule-dependent transcytosis of the aquaporin-2 water channel by Yui, Naofumi, Lu, Hua A J, Chen, Ying, Nomura, Naohiro, Bouley, Richard, Brown, Dennis

“…The aquaporin-2 (AQP2) water channel relocates mainly to the apical plasma membrane of collecting duct principal cells after vasopressin (VP) stimulation. AQP2…”
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Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure by Ohta, Akihito, Rai, Tatemitsu, Yui, Naofumi, Chiga, Motoko, Yang, Sung-Sen, Lin, Shih-Hua, Sohara, Eisei, Sasaki, Sei, Uchida, Shinichi

“…We recently generated Wnk4D561A/+ knockin mice and found that a major pathogenesis of pseudohypoaldosteronism type II was the activation of the OSR1/SPAK…”
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Chlorpromazine Induces Basolateral Aquaporin-2 Accumulation via F-Actin Depolymerization and Blockade of Endocytosis in Renal Epithelial Cells by Bouley, Richard, Yui, Naofumi, Terlouw, Abby, Cheung, Pui W, Brown, Dennis

“…We previously showed that in polarized Madin-Darby canine kidney (MDCK) cells, aquaporin-2 (AQP2) is continuously targeted to the basolateral plasma membrane…”
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Two Cases of Hemodialysis-associated Chronic Portal-systemic Shunt Encephalopathy (CPSE) with Opposite Changes in the Blood Ammonia Concentrations during Hemodialysis: A Case Report and Literature Review by Oi, Katsuyuki, Okado, Tomokazu, Togo, Hisako, Iimori, Soichiro, Yui, Naofumi, Sohara, Eisei, Kanda, Eiichiro, Rai, Tatemitsu, Sasaki, Sei, Uchida, Shinichi

“…The onset of hyperammonemia due to the flow of ammonia-rich portal vein blood through a portal-systemic shunt causes a type of encephalopathy known as chronic…”
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Bence-Jones Protein λ-type Multiple Myeloma Patient Withdrawn from Maintenance Hemodialysis after Long-term Bortezomib and Dexamethasone Therapy by Yamaguchi, Wakaba, Yui, Naofumi, Nagao, Toshikage, Oshikawa, Gaku, Negi, Mariko, Iimori, Soichiro, Okado, Tomokazu, Rai, Tatemitsu, Uchida, Shinichi

“…The effectiveness of bortezomib treatment for multiple myeloma (MM) is well established. However, the protocol by which maintenance therapy using bortezomib…”
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AQP2 is necessary for vasopressin- and forskolin-mediated filamentous actin depolymerization in renal epithelial cells by Yui, Naofumi, Lu, Hua Jenny, Bouley, Richard, Brown, Dennis

“…Remodeling of the actin cytoskeleton is required for vasopressin (VP)-induced aquaporin 2 (AQP2) trafficking. Here, we asked whether VP and forskolin…”
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FAPP2 is required for aquaporin-2 apical sorting at trans-Golgi network in polarized MDCK cells by Yui, Naofumi, Okutsu, Rie, Sohara, Eisei, Rai, Tatemitsu, Ohta, Akihito, Noda, Yumi, Sasaki, Sei, Uchida, Shinichi

“…FAPP2 is an adaptor protein of phosphatidylinositol-4-phosphate and is involved in the transport of some apical cargos from the trans-Golgi network (TGN). To…”
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Actin directly interacts with different membrane channel proteins and influences channel activities: AQP2 as a model by Sasaki, Sei, Yui, Naofumi, Noda, Yumi

“…The interplay between actin and 10 membrane channel proteins that have been shown to directly bind to actin are reviewed. The 10 membrane channel proteins…”
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Aquaporin-2 Ser-261 phosphorylation is regulated in combination with Ser-256 and Ser-269 phosphorylation by Yui, Naofumi, Sasaki, Sei, Uchida, Shinichi

“…Aquaporin-2 (AQP2) is a water channel in collecting duct principal cells in the kidney. Vasopressin catalyzes AQP2 phosphorylation at several serine sites in…”
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LRBA signalosomes activate vasopressin‐induced AQP2 trafficking at recycling endosomes by Yanagawa, Hideki, Hara, Yu, Ando, Fumiaki, Suzuki, Soichiro, Fujiki, Tamami, Oikawa, Daisuke, Yui, Naofumi, Mandai, Shintaro, Mori, Yutaro, Susa, Koichiro, Mori, Takayasu, Sohara, Eisei, Tokunaga, Fuminori, Uchida, Shinichi

“…Aquaporin‐2 (AQP2) water channels are proteins that are recycled between intracellular vesicles and the apical plasma membrane in renal collecting ducts…”
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Anaemia management and mortality risk in newly visiting patients with chronic kidney disease in Japan: The CKD-ROUTE study by Iimori, Soichiro, Naito, Shotaro, Noda, Yumi, Nishida, Hidenori, Kihira, Hiromi, Yui, Naofumi, Okado, Tomokazu, Sasaki, Sei, Uchida, Shinichi, Rai, Tatemitsu

“…Aim To investigate the association between iron deficiency anaemia and mortality risk and assess the changes in anaemia and iron status after primary…”
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Treatment with 17-allylamino-17-demethoxygeldanamycin ameliorated symptoms of Bartter syndrome type IV caused by mutated Bsnd in mice by Nomura, Naohiro, Kamiya, Kazusaku, Ikeda, Katsuhisa, Yui, Naofumi, Chiga, Motoko, Sohara, Eisei, Rai, Tatemitu, Sakaki, Sei, Uchida, Shinich

“…•R8L barttin knock-in mice exhibited sensorineural hearing impairment.•Plasma membrane expression of R8L barttin was impaired in marginal cells of the inner…”
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Retroperitoneal Fibrosis in Chronic Kidney Disease by Yoshizaki, Yuki, Yui, Naofumi, Okado, Tomokazu, Ishigami, Junichi, Iimori, Soichiro, Oi, Katusyuki, Sohara, Eisei, Sasaki, Sei, Rai, Tatemitsu, Uchida, Shinichi

“…We report two cases of retroperitoneal fibrosis that emerged during a clinical course of moderate chronic kidney disease. In both cases, we observed an…”
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