Search Results - "Yuen, S T"

Rapid isolation of urinary exosomal biomarkers using a nanomembrane ultrafiltration concentrator by Cheruvanky, Anita, Zhou, Hua, Pisitkun, Trairak, Kopp, Jeffrey B, Knepper, Mark A, Yuen, Peter S T, Star, Robert A

“…Urinary exosomes are excreted from all nephron segments and may serve as biomarkers for classifying renal diseases. Isolation of urinary exosomes by the…”
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The effect of continuous intravenous norepinephrine infusion on systemic hemodynamics in a telemetrically-monitored mouse model of sepsis by Yamashita, Tetsushi, Street, Jonathan M, Halasa, Brianna C, Naito, Yoshitaka, Tsuji, Takayuki, Tsuji, Naoko, Hayase, Naoki, Yuen, Peter S. T, Star, Robert A

“…Sepsis, a life-threatening organ dysfunction, results from dysregulated host responses to infection and still has a high incidence and mortality. Although…”
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IL-18 deficiency ameliorates the progression from AKI to CKD by Luan, Junjun, Fu, Jingqi, Jiao, Congcong, Hao, Xiangnan, Feng, Zixuan, Zhu, Lingzi, Zhang, Yixiao, Zhou, Guangyu, Li, Hongyu, Yang, Wei, Yuen, Peter S. T., Kopp, Jeffrey B., Pi, Jingbo, Zhou, Hua

“…Inflammation is an important factor in the progression from acute kidney injury (AKI) to chronic kidney disease (CKD). The role of interleukin (IL)-18 in this…”
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Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury by Yasuda, Hideo, Leelahavanichkul, Asada, Tsunoda, Shinichiro, Dear, James W, Takahashi, Yoshiyuki, Ito, Shuichi, Hu, Xuzhen, Zhou, Hua, Doi, Kent, Childs, Richard, Klinman, Dennis M, Yuen, Peter S T, Star, Robert A

“…Mortality from sepsis has remained high despite recent advances in supportive and targeted therapies. Toll-like receptors (TLRs) sense bacterial products and…”
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Calpastatin Controls Polymicrobial Sepsis by Limiting Procoagulant Microparticle Release by ZAFRANI, Lara, GEROTZIAFAS, Grigoris, ELALAMY, Ismail, MILLER, Jeffrey L, STAR, Robert A, YUEN, Peter S. T, BAUD, Laurent, BYRNES, Colleen, XUZHEN HU, PEREZ, Joelle, LEVI, Charlène, PLACIER, Sandrine, LETAVERNIER, Emmanuel, LEELAHAVANICHKUL, Asada, HAYMANN, Jean-Philippe

“…Sepsis, a leading cause of death worldwide, involves widespread activation of inflammation, massive activation of coagulation, and lymphocyte apoptosis…”
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Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice by Miyaji, Takehiko, Hu, Xuzhen, Yuen, Peter S.T., Muramatsu, Yasunari, Iyer, Swarnalatha, Hewitt, Stephen M., Star, Robert A.

“…Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice. Sepsis is a common cause of acute renal failure (ARF). The…”
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TLR4 mutant mice are protected from renal fibrosis and chronic kidney disease progression by Souza, Ana C. P., Tsuji, Takayuki, Baranova, Irina N., Bocharov, Alexander V., Wilkins, Kenneth J., Street, Jonathan M., Alvarez‐Prats, Alejandro, Hu, Xuzhen, Eggerman, Thomas, Yuen, Peter S. T., Star, Robert A.

“…Chronic kidney disease (CKD) is associated with persistent low‐grade inflammation and immunosuppression. In this study we tested the role of Toll‐like receptor…”
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Gut Leakage of Fungal-Derived Inflammatory Mediators: Part of a Gut-Liver-Kidney Axis in Bacterial Sepsis by Amornphimoltham, Panomwat, Yuen, Peter S. T., Star, Robert A., Leelahavanichkul, Asada

“…Sepsis is a life-threatening response to systemic infection. In addition to frank gastrointestinal (GI) rupture/puncture, sepsis can also be exacerbated by…”
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Methyl-2-acetamidoacrylate, an ethyl pyruvate analog, decreases sepsis-induced acute kidney injury in mice by Leelahavanichkul, Asada, Yasuda, Hideo, Doi, Kent, Hu, Xuzhen, Zhou, Hua, Yuen, Peter S T, Star, Robert A

“…We tested the anti-inflammatory agent methyl-2-acetamidoacrylate (M2AA), an ethyl pyruvate analog, in a cecal ligation-and-puncture (CLP) model of sepsis in…”
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Microparticles during sepsis: target, canary or cure? by Zafrani, Lara, Ince, Can, Yuen, Peter S. T.

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Electrocatalytic activity of iridium oxide nanoparticles coated on carbon for oxygen reduction as cathode catalyst in polymer electrolyte fuel cell by Chang, C.H., Yuen, T.S., Nagao, Y., Yugami, H.

“…The iridium oxide nanoparticles supported on Vulcan XC-72 porous carbon were prepared for cathode catalyst in polymer electrolyte fuel cell (PEFC). The…”
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Urine Exosome Isolation and Characterization by Street, Jonathan M, Koritzinsky, Erik H, Glispie, Deonna M, Yuen, Peter S T

“…Exosomes are nanometer-scale, membrane-enclosed vesicles that can potentially be used to detect nephrotoxicity, and reveal the subsequent response of the…”
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BRAF and NRAS mutations are uncommon in melanomas arising in diverse internal organs by Wong, C W, Fan, Y S, Chan, T L, Chan, A S W, Ho, L C, Ma, T K F, Yuen, S T, Leung, S Y

“…Background: Malignant melanoma arising from different body compartments may be associated with differing aetiological factors and clinical behaviour, and may…”
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Municipal solid waste management in the Southern Province of Sri Lanka: Problems, issues and challenges by Vidanaarachchi, Chandana K., Yuen, Samuel T.S., Pilapitiya, Sumith

“…This paper describes the problems, issues and challenges faced by Sri Lanka based on the outcome of a recent study conducted in the country’s Southern…”
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A simplified method for HPLC determination of creatinine in mouse serum by Yuen, Peter S T, Dunn, Stephen R, Miyaji, Takehiko, Yasuda, Hideo, Sharma, Kumar, Star, Robert A

“…Mouse models are frequently used to study renal function. However, mouse serum contains chromagens that interfere with standard picric acid-based assays for…”
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Experimental models of acute kidney injury for translational research by Hukriede, Neil A., Soranno, Danielle E., Sander, Veronika, Perreau, Tayla, Starr, Michelle C., Yuen, Peter S. T., Siskind, Leah J., Hutchens, Michael P., Davidson, Alan J., Burmeister, David M., Faubel, Sarah, de Caestecker, Mark P.

“…Preclinical models of human disease provide powerful tools for therapeutic discovery but have limitations. This problem is especially apparent in the field of…”
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Human SR-BI and SR-BII Potentiate Lipopolysaccharide-Induced Inflammation and Acute Liver and Kidney Injury in Mice by Baranova, Irina N, Souza, Ana C P, Bocharov, Alexander V, Vishnyakova, Tatyana G, Hu, Xuzhen, Vaisman, Boris L, Amar, Marcelo J, Chen, Zhigang, Kost, Yana, Remaley, Alan T, Patterson, Amy P, Yuen, Peter S T, Star, Robert A, Eggerman, Thomas L

“…The class B scavenger receptors BI (SR-BI) and BII (SR-BII) are high-density lipoprotein receptors that recognize various pathogens, including bacteria and…”
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Reduced Production of Creatinine Limits Its Use as Marker of Kidney Injury in Sepsis by DOI, Kent, YUEN, Peter S. T, EISNER, Christoph, XUZHEN HU, LEELAHAVANICHKUL, Asada, SCHNERMANN, Jürgen, STAR, Robert A

“…Although diagnosis and staging of acute kidney injury uses serum creatinine, acute changes in creatinine lag behind both renal injury and recovery. The risk…”
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Quantification of Exosomes by Koritzinsky, Erik H., Street, Jonathan M., Star, Robert A., Yuen, Peter S.T.

“…Exosomes are released by cells as self‐contained vesicles with an intact lipid bilayer that encapsulates a small portion of the parent cell. Exosomes have been…”
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Comparison of serum creatinine and serum cystatin C as biomarkers to detect sepsis-induced acute kidney injury and to predict mortality in CD-1 mice by Leelahavanichkul, Asada, Souza, Ana Carolina P, Street, Jonathan M, Hsu, Victor, Tsuji, Takayuki, Doi, Kent, Li, Lingli, Hu, Xuzhen, Zhou, Hua, Kumar, Parag, Schnermann, Jürgen, Star, Robert A, Yuen, Peter S T

“…Acute kidney injury (AKI) dramatically increases sepsis mortality, but AKI diagnosis is delayed when based on serum creatinine (SCr) changes, due in part, to…”
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