Search Results - "Yuen, P S T"

Exosomal Fetuin-A identified by proteomics: A novel urinary biomarker for detecting acute kidney injury by Zhou, H., Pisitkun, T., Aponte, A., Yuen, P.S.T., Hoffert, J.D., Yasuda, H., Hu, X., Chawla, L., Shen, R.-F., Knepper, M.A., Star, R.A.

“…Urinary exosomes containing apical membrane and intracellular fluid are normally secreted into the urine from all nephron segments, and may carry protein…”
Get full text

AP214, an analogue of α-melanocyte-stimulating hormone, ameliorates sepsis-induced acute kidney injury and mortality by Doi, K., Hu, X., Yuen, P.S.T., Leelahavanichkul, A., Yasuda, H., Kim, S.M., Schnermann, J., Jonassen, T.E.N., Frøkiær, J., Nielsen, S., Star, R.A.

“…Sepsis remains a serious problem in critically ill patients with the mortality increasing to over half when there is attendant acute kidney injury…”
Get full text

Connective Tissue Growth Factor is a Biomarker and Mediator of Kidney Allograft Fibrosis by Cheng, O., Thuillier, R., Sampson, E., Schultz, G., Ruiz, P., Zhang, X., Yuen, P.S.T., Mannon, R.B.

“…Chronic allograft nephropathy (CAN) is a leading cause of kidney graft failure following transplantation. Its causes are complex and include both immunological…”
Get full text

Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure by Holly, M.K., Dear, J.W., Hu, X., Schechter, A.N., Gladwin, M.T., Hewitt, S.M., Yuen, P.S.T., Star, R.A.

“…Sepsis is one of the common causes of acute renal failure (ARF). The objective of this study was to identify new biomarkers and therapeutic targets. We present…”
Get full text

Urine Exosomes: An Emerging Trove of Biomarkers by Street, J M, Koritzinsky, E H, Glispie, D M, Star, R A, Yuen, P S T

“…Exosomes are released by most cells and can be isolated from all biofluids including urine. Exosomes are small vesicles formed as part of the endosomal pathway…”
Get full text

Exosomes from human saliva as a source of microRNA biomarkers by Michael, A, Bajracharya, SD, Yuen, PST, Zhou, H, Star, RA, Illei, GG, Alevizos, I

“…Objective:  The aim of this study was to examine the presence of microRNAs (miRNAs) within exosomes isolated from human saliva and to optimize and test methods…”
Get full text

Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery by Zhou, H., Yuen, P.S.T., Pisitkun, T., Gonzales, P.A., Yasuda, H., Dear, J.W., Gross, P., Knepper, M.A., Star, R.A.

“…Urinary exosomes containing apical membrane and intracellular fluid are normally secreted into the urine from all nephron segments, and may carry protein…”
Get full text

Simvastatin improves sepsis-induced mortality and acute kidney injury via renal vascular effects by Yasuda, H., Yuen, P.S.T., Hu, X., Zhou, H., Star, R.A.

“…Acute kidney injury (AKI) occurs in about half of patients in septic shock and the mortality of AKI with sepsis is extremely high. An effective therapeutic…”
Get full text

Sepsis-induced organ failure is mediated by different pathways in the kidney and liver: Acute renal failure is dependent on MyD88 but not renal cell apoptosis by Dear, J.W., Yasuda, H., Hu, X., Hieny, S., Yuen, P.S.T., Hewitt, S.M., Sher, A., Star, R.A.

“…Toll-like receptors (TLRs) are important in sepsis. Myeloid differentiation factor 88 (MyD88) is a key molecule involved in signal transduction by multiple…”
Get full text

Setting the stage for acute-on-chronic kidney injury by Dear, J.W., Yuen, P.S.T.

“…Acute-on-chronic kidney disease will be familiar to many nephrologists. Hsu et al. quantify the risk of acute-on-chronic disease across the stages of…”
Get full text

Guanylyl cyclase-linked receptors by YUEN, P. S. T, GARBERS, D. L

Get full text

AP214, an analogue of [alpha]-melanocyte-stimulating hormone, ameliorates sepsis-induced acute kidney injury and mortality by Doi, K, Hu, X, Yuen, P S T, Leelahavanichkul, A, Yasuda, H, Kim, S M, Schnermann, J, Jonassen, T E N, Frøkiær, J, Nielsen, S, Star, R A

“…Sepsis remains a serious problem in critically ill patients with the mortality increasing to over half when there is attendant acute kidney injury…”
Get full text

The risk of acute renal failure in patients with chronic kidney disease. Commentary by DEAR, J. W, YUEN, P. S. T, HSU, C. Y, ORDONEZ, J. D, CHERTOW, G. M, FAN, D, MCCULLOCH, C. E, GO, A. S

Get full text

Guanylyl cyclase is a heat-stable enterotoxin receptor by Schulz, S, Green, C K, Yuen, P S, Garbers, D L

“…Plasma membrane forms of guanylyl cyclase have been shown to function as natriuretic peptide receptors. We describe a new clone (GC-C) encoding a guanylyl…”
Get more information

A new form of guanylyl cyclase is preferentially expressed in rat kidney by Yuen, Peter S. T, Potter, Lincoln R, Garbers, David L

“…On the basis of the conserved amino acid sequences of the catalytic domain of both soluble and plasma membrane forms of guanylyl cyclase, we have used the…”
Get full text

RNA: a method to specifically inhibit PCR amplification of known members of a multigene family by degenerate primers by Yuen, P S, Brooks, K M, Li, Y

“…The polymerase chain reaction (PCR) is a versatile method to amplify specific DNA with oligonucleotide primers. By designing degenerate PCR primers based on…”
Get full text

Dominant negative mutants of nitric oxide-sensitive guanylyl cyclase by YUEN, P. S. T, DOOLITTLE, L. K, GARBERS, D. L

“…Since a nitric oxide-sensitive form of guanylyl cyclase exists as a heterodimer, mutations disrupting catalysis but not heterodimer formation could serve as…”
Get full text

Differential expression of mRNA for guanylyl cyclase-linked endothelium-derived relaxing factor receptor subunits in rats kidney by UJIIE, K, DREWETT, J. G, YUEN, P. S. T, STAR, R. A

Get full text

Non-identity of cGMP as the guanine nucleotide stimulated to bind to ROS by light and ATP by Yuen, P S, Graeff, R M, Walseth, T F, Goldberg, N D

“…Light, in the presence of ATP, has been reported to stimulate cGMP binding to a 58 kDa protein in ROS (rod outer segments, Fesenko and Krapivinsky, 1986b,…”
Get more information