Search Results - "Yue, Yale"
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Melanin-Like Nanomedicine in Photothermal Therapy Applications
Published in International journal of molecular sciences (01-01-2021)“…Photothermal therapy (PTT) mediated by nanomaterial has become an attractive tumor treatment method due to its obvious advantages. Among various nanomaterials,…”
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Modular-designed engineered bacteria for precision tumor immunotherapy via spatiotemporal manipulation by magnetic field
Published in Nature communications (23-03-2023)“…Micro-nano biorobots based on bacteria have demonstrated great potential for tumor diagnosis and treatment. The bacterial gene expression and drug release…”
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Functional Immune Cell‐Derived Exosomes Engineered for the Trilogy of Radiotherapy Sensitization
Published in Advanced science (01-08-2022)“…The limited efficacy of radiotherapy leads to radio‐resistance and high rates of tumor recurrence and metastasis, which is caused by tumor hypoxia, rapid DNA…”
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Author Correction: Modular-designed engineered bacteria for precision tumor immunotherapy via spatiotemporal manipulation by magnetic field
Published in Nature communications (10-07-2023)Get full text
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Personalized cancer vaccines from bacteria-derived outer membrane vesicles with antibody-mediated persistent uptake by dendritic cells
Published in Fundamental research (Beijing) (01-01-2022)“…Nanocarriers with intrinsic immune adjuvant properties can activate the innate immune system while delivering tumor antigen, thus efficiently facilitating…”
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Biomimetic Nanoparticles Carrying a Repolarization Agent of Tumor-Associated Macrophages for Remodeling of the Inflammatory Microenvironment Following Photothermal Therapy
Published in ACS nano (28-09-2021)“…The complete regression of residual tumors after photothermal therapy (PTT) depends on the activation and recognition of the immune system. However, the…”
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Engineered Bacterial Outer Membrane Vesicles as Controllable Two‐Way Adaptors to Activate Macrophage Phagocytosis for Improved Tumor Immunotherapy
Published in Advanced materials (Weinheim) (01-10-2022)“…The most immune cells infiltrating tumor microenvironment (TME), tumor‐associated macrophages (TAMs) closely resemble immunosuppressive M2‐polarized…”
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Antigen Capture and Immune Modulation by Bacterial Outer Membrane Vesicles as In Situ Vaccine for Cancer Immunotherapy Post‐Photothermal Therapy
Published in Small (Weinheim an der Bergstrasse, Germany) (01-04-2022)“…Tumor antigens released from tumor cells after local photothermal therapy (PTT) can activate the tumor‐specific immune responses, which are critical for…”
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Rapid Surface Display of mRNA Antigens by Bacteria‐Derived Outer Membrane Vesicles for a Personalized Tumor Vaccine
Published in Advanced materials (Weinheim) (01-05-2022)“…Therapeutic mRNA vaccination is an attractive approach to trigger antitumor immunity. However, the mRNA delivery technology for customized tumor vaccine is…”
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Rapid Capture and Nondestructive Release of Extracellular Vesicles Using Aptamer-Based Magnetic Isolation
Published in ACS sensors (24-05-2019)“…Extracellular vesicles (EVs) play important roles in cell–cell communication by transferring cargo proteins and nucleic acids between cells. Due to their small…”
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Self‐Oxygenated Biomimetic Nanozyme for Tumor Catalytic Immunotherapy
Published in Advanced functional materials (31-10-2024)“…Abstract The treatment of solid tumors remains a significant challenge due to the complex, immunosuppressive tumor microenvironment (TME). This manuscript…”
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Antigen-bearing outer membrane vesicles as tumour vaccines produced in situ by ingested genetically engineered bacteria
Published in Nature biomedical engineering (01-07-2022)“…The complex gastrointestinal environment and the intestinal epithelial barrier constrain the design and effectiveness of orally administered tumour vaccines…”
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Intelligent Responsive Nanoparticles with Multilevel Triggered Drug Penetration for Tumor Photochemotherapy
Published in ACS applied materials & interfaces (20-09-2023)“…Nanomedicines have contradictory size requirements to overcome systemic barriers and penetrate the tumor extracellular matrix (ECM). Larger-sized nanoparticles…”
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Bacteria-derived nanovesicles enhance tumour vaccination by trained immunity
Published in Nature nanotechnology (01-03-2024)“…Trained immunity enhances the responsiveness of immune cells to subsequent infections or vaccinations. Here we demonstrate that pre-vaccination with…”
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Restoration of Sinusoid Fenestrae Followed by Targeted Nanoassembly Delivery of an Anti‐Fibrotic Agent Improves Treatment Efficacy in Liver Fibrosis
Published in Advanced materials (Weinheim) (01-04-2023)“…During the onset of liver fibrosis, capillarized liver sinusoidal endothelial cells (LSECs) limit substance exchange between the blood and the Disse space,…”
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Immunogenic cell death effects induced by doxorubicin improved chemo-immunotherapy via restoration of granzyme B activity
Published in Nano research (01-12-2023)“…Chemotherapy remains one of the irreplaceable treatments for cancer therapy. The use of immunogenic cell death (ICD)-inducing chemotherapeutic drugs offers a…”
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Normalizing the Immune Macroenvironment via Debulking Surgery to Strengthen Tumor Nanovaccine Efficacy and Eliminate Metastasis
Published in ACS nano (10-01-2023)“…In tumor nanovaccines, nanocarriers enhance the delivery of tumor antigens to antigen-presenting cells (APCs), thereby ensuring the robust activation of tumor…”
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Modularly designed peptide-based nanomedicine inhibits angiogenesis to enhance chemotherapy for post-surgical recurrence of esophageal squamous cell carcinomas
Published in Nano research (01-05-2023)“…Traditional surgical treatment is difficult to thoroughly remove esophageal squamous cell carcinomas (ESCC), and postoperative recurrence caused by residual…”
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Restoration of Sinusoid Fenestrae Followed by Targeted Nanoassembly Delivery of an Anti‐Fibrotic Agent Improves Treatment Efficacy in Liver Fibrosis (Adv. Mater. 17/2023)
Published in Advanced materials (Weinheim) (01-04-2023)“…Drug Delivery In article number 2212206, Ying Zhao, Xiaolong Qi, Guangjun Nie, and co‐workers propose a liver sinusoid capillarization and hepatic stellate…”
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Publisher Erratum to: Mismatched graphic abstracts in previously 2 published articles
Published in Nano research (01-07-2023)“…The graphic abstracts have been mismatched for this two articles during production by vendor, and should have appeared as below…”
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