Search Results - "Yue, Xinping"

Epithelial Deletion of Sulf2 Exacerbates Bleomycin-Induced Lung Injury, Inflammation, and Mortality by Yue, Xinping

“…Epithelial injury has been proposed to be the initiating factor in the pathogenesis of idiopathic pulmonary fibrosis (IPF). We have shown previously that…”
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ACE2 mouse models: a toolbox for cardiovascular and pulmonary research by Jia, Hongpeng, Yue, Xinping, Lazartigues, Eric

“…Angiotensin-converting enzyme 2 (ACE2) has been identified as the host entry receptor for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
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Nicotine and the renin-angiotensin system by Oakes, Joshua M, Fuchs, Robert M, Gardner, Jason D, Lazartigues, Eric, Yue, Xinping

“…Cigarette smoking is the single most important risk factor for the development of cardiovascular and pulmonary diseases (CVPD). Although cigarette smoking has…”
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Differential Protein Expression Profiles of Bronchoalveolar Lavage Fluid Following Lipopolysaccharide-Induced Direct and Indirect Lung Injury in Mice by Yue, Xinping, Guidry, Jessie J

“…The pathogenic mechanisms of acute lung injury due to direct and indirect pulmonary insults are incompletely understood. Using an unbiased, discovery and…”
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Effects of Chronic Nicotine Inhalation on Systemic and Pulmonary Blood Pressure and Right Ventricular Remodeling in Mice by Oakes, Joshua M., Xu, Jiaxi, Morris, Tamara M., Fried, Nicholas D., Pearson, Charlotte S., Lobell, Thomas D., Gilpin, Nicholas W., Lazartigues, Eric, Gardner, Jason D., Yue, Xinping

“…Cigarette smoking is the single most important risk factor for the development of cardiovascular and pulmonary diseases; however, the role of nicotine in the…”
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Up-regulation of heparan sulfate 6-O-sulfation in idiopathic pulmonary fibrosis by Lu, Jingning, Auduong, Linda, White, Eric S, Yue, Xinping

“…Heparan sulfate proteoglycans (HSPGs) are integral components of the lung. Changes in HSPGs have been documented in idiopathic pulmonary fibrosis (IPF). Many…”
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Angiotensin-Converting Enzyme 2 Overexpression in the Subfornical Organ Prevents the Angiotensin II–Mediated Pressor and Drinking Responses and Is Associated With Angiotensin II Type 1 Receptor Downregulation by Feng, Yumei, Yue, Xinping, Xia, Huijing, Bindom, Sharell M, Hickman, Peter J, Filipeanu, Catalin M, Wu, Guangyu, Lazartigues, Eric

“…We recently reported the presence of angiotensin-converting enzyme (ACE)2 in brain regions controlling cardiovascular function; however, the role of ACE2 in…”
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Nicotine Downregulates the Compensatory Angiotensin-Converting Enzyme 2/Angiotensin Type 2 Receptor of the Renin-Angiotensin System by Yue, Xinping, Basting, Tyler M, Flanagan, Thomas W, Xu, Jiaxi, Lobell, Thomas D, Gilpin, Nicholas W, Gardner, Jason D, Lazartigues, Eric

“…Smoking is a major risk factor for the development of cardiovascular and pulmonary diseases. The importance of the renin-angiotensin system in the development…”
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Overexpression of Sulf2 in idiopathic pulmonary fibrosis by Yue, Xinping, Lu, Jingning, Auduong, Linda, Sides, Mark D, Lasky, Joseph A

“…Previously, we have shown that heparan sulfate (HS) 6-O-endosulfatase 1 (Sulf1) is a transforming growth factor-β1 (TGF-β1)-responsive gene in normal human…”
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Nicotine and novel tobacco products drive adverse cardiac remodeling and dysfunction in preclinical studies by Fried, Nicholas D, Oakes, Joshua M, Whitehead, Anna K, Lazartigues, Eric, Yue, Xinping, Gardner, Jason D

“…The heart undergoes structural and functional changes in response to injury and hemodynamic stress known as cardiac remodeling. Cardiac remodeling often…”
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HSulf-1 and HSulf-2 Are Potent Inhibitors of Myeloma Tumor Growth in Vivo by Dai, Yuemeng, Yang, Yang, MacLeod, Veronica, Yue, Xinping, Rapraeger, Alan C., Shriver, Zachary, Venkataraman, Ganesh, Sasisekharan, Ram, Sanderson, Ralph D.

“…To participate as co-receptor in growth factor signaling, heparan sulfate must have specific structural features. Recent studies show that when the levels of…”
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Transforming Growth Factor-β1 Induces Heparan Sulfate 6-O-Endosulfatase 1 Expression in Vitro and in Vivo by Yue, Xinping, Li, Xian, Nguyen, Hong T., Chin, Dawn R., Sullivan, Deborah E., Lasky, Joseph A.

“…Transforming growth factor (TGF)-β1 plays an important role in the development of pulmonary fibrosis. In this study we examined the relationship between TGF-β1…”
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Role of Heparan Sulfate 6-O-Endosulfatases in Hematopoiesis by Whitehead, Anna K, Yue, Xinping

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Abstract P159: Conditional deletion of ADAM17 (A disintegrin and metalloprotease 17) in microglia attenuates hypertension and associated inflammation by Mohan, Uma Priya, Dinh, Paula, Yue, Xinping, Lazartigues, Eric

“…Abstract only Microglia, the resident immune cell in the brain, contributes to neuroinflammation and neurogenic hypertension by secreting various cytokines and…”
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Nicotine and vascular dysfunction by Whitehead, Anna K., Erwin, Abigail P., Yue, Xinping

“…Cigarette smoking is the single most important risk factor for the development of cardiovascular diseases (CVDs). However, the role of nicotine, the addictive…”
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Myeloid Sulf Deletion and Immune Dysfunction in Multiple Sulfatase Deficiency by Whitehead, Anna K., Yue, Xinping

“…Introduction Multiple sulfatase deficiency (MSD) is a rare autosomal recessive disease due to pathogenic mutations in the sulfatase‐modifying factor 1 (SUMF1)…”
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Obesity exacerbates SARS‐CoV‐2 infection in K18‐hACE2 mice by Berdasco, Clara, Whitehead, Anna, Qin, Xuebin, Yue, Xinping, Lazartigues, Eric

“…Hypertension and obesity are considered risk factors for severe coronavirus disease 2019 (COVID‐19), caused by the severe acute respiratory syndrome…”
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Abstract 058: ACE2 Ubiquitination Regulates Neuronal Activity In Hypertension by Mohammed, Mazher, Elgazzaz, Mona, Yue, Xinping, Filipeanu, Catalin, Lazartigues, Eric D

“…Abstract only ACE2 expression on GABAergic neurons could maintain the inhibitory tone over pre-sympathetic neurons in the paraventricular nucleus (PVN) and…”
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Cardiovascular dysfunction induced by combined exposure to nicotine inhalation and high fat diet by Whitehead, Anna, Li, Zhen, LaPenna, Kyle, Sharp, Thomas, Lefer, David, Lazartigues, Eric, Yue, Xinping

“…Abstract only Cardiovascular diseases (CVD) are the leading cause of death worldwide, and smoking remains the most significant preventable risk factor. The…”
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The Effects of Nicotine on Cardiac Function and Structure by Oakes, Joshua, Knowling, Joselyn, Lazartigues, Eric, Yue, Xinping, Gardner, Jason

“…Nicotine is the addictive chemical in tobacco‐related products, such as cigarettes, water pipes, e‐cigs, and chewing tobacco. While the effects of smoke from…”
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