Search Results - "Yue, Xianlin"
-
1
mtDNA release promotes cGAS-STING activation and accelerated aging of postmitotic muscle cells
Published in Cell death & disease (23-07-2024)“…The mechanism regulating cellular senescence of postmitotic muscle cells is still unknown. cGAS-STING innate immune signaling was found to mediate cellular…”
Get full text
Journal Article -
2
Reduction of senescent fibro‐adipogenic progenitors in progeria‐aged muscle by senolytics rescues the function of muscle stem cells
Published in Journal of cachexia, sarcopenia and muscle (01-12-2022)“…Background Fibro‐adipogenic progenitors (FAPs) in the muscles have been found to interact closely with muscle progenitor/stem cells (MPCs) and facilitate…”
Get full text
Journal Article -
3
Nuclear softening mediated by Sun2 suppression delays mechanical stress-induced cellular senescence
Published in Cell death discovery (17-05-2023)“…Nuclear decoupling and softening are the main cellular mechanisms to resist mechanical stress-induced nuclear/DNA damage, however, its molecular mechanisms…”
Get full text
Journal Article -
4
Dimethoxytolyl propylresorcinol induces apoptosis and mitophagy in human leukemia cells through the PI3K/AKT pathway
Published in Journal of Cancer (2024)“…Dimethoxytolyl propylresorcinol (UP302), a natural compound extracted from owing to its tyrosinase inhibitory and strong antioxidant properties, is used in…”
Get full text
Journal Article -
5
Senolytic elimination of senescent macrophages restores muscle stem cell function in severely dystrophic muscle
Published in Aging (Albany, NY.) (15-10-2022)“…The aging of the immune system, or immunosenescence, was recently verified to have a causal role in driving the aging of solid organs, while the senolytic…”
Get full text
Journal Article -
6
Bioprinted Notch ligand to function as stem cell niche improves muscle regeneration in dystrophic muscle
Published in International journal of bioprinting (01-01-2023)“…299In Duchenne muscular dystrophy, dystrophic muscle phenotypes are closely associated with the exhaustion of muscle stem cells. Transplantation of muscle stem…”
Get full text
Journal Article