Search Results - "Yue, Kevin K.M"
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A delivery system specifically approaching bone resorption surfaces to facilitate therapeutic modulation of microRNAs in osteoclasts
Published in Biomaterials (01-06-2015)“…Abstract Dysregulated microRNAs in osteoclasts could cause many skeletal diseases. The therapeutic manipulation of these pathogenic microRNAs necessitates…”
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Therapeutic RNA interference targeting CKIP-1 with a cross-species sequence to stimulate bone formation
Published in Bone (New York, N.Y.) (01-02-2014)“…Abstract Objectives Casein kinase 2 interacting protein 1 (CKIP-1) is a newly discovered intracellular negative regulator of bone formation without affecting…”
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Altered expression of serum protein in ginsenoside Re-treated diabetic rats detected by SELDI-TOF MS
Published in Journal of ethnopharmacology (24-11-2006)“…Diabetes mellitus (DM) is now a global health problem, however, its pathogenesis has not yet been fully deciphered. Even though modern medicine has great…”
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Redox changes precede the occurrence of oxidative stress in eyes and aorta, but not in kidneys of diabetic rats
Published in Life sciences (1973) (03-10-2003)“…Almost all diabetic complications are known to be associated with vascular dysfunctions of different tissues. Oxidative stress, on the other hand, has been…”
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Glucose-induced oxidative stress in vascular contractile cells: comparison of aortic smooth muscle cells and retinal pericytes
Published in Diabetes (New York, N.Y.) (01-05-1998)“…Glucose-induced oxidative stress in vascular contractile cells: comparison of aortic smooth muscle cells and retinal pericytes. P C Sharpe , W H Liu , K K Yue…”
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Ginsenoside Re of Panax ginseng possesses significant antioxidant and antihyperlipidemic efficacies in streptozotocin-induced diabetic rats
Published in European journal of pharmacology (21-11-2006)“…Diabetes mellitus is characterized by hyperglycemia and complications affecting the eye, kidney, nerve and blood vessel. We have previously demonstrated the…”
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Ginsenosides attenuate methylglyoxal-induced impairment of insulin signaling and subsequent apoptosis in primary astrocytes
Published in Neuropharmacology (01-10-2014)“…Diabetes mellitus (DM), which is characterized by chronic hyperglycemia, is known to increase the risk of neurodegeneration. In type 2 diabetes, hyperglycemia…”
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Methylglyoxal-induced neuroinflammatory response in in vitro astrocytic cultures and hippocampus of experimental animals
Published in Metabolic brain disease (01-10-2016)“…Diabetes mellitus is characterized by chronic hyperglycemia and its diverse complications. Hyperglycemia is associated with inflammatory responses in different…”
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Modulation of endoplasmic reticulum chaperone GRP78 by high glucose in hippocampus of streptozotocin-induced diabetic mice and C6 astrocytic cells
Published in Neurochemistry international (01-11-2013)“…•STZ-type 1 diabetic mice showed astrocytic activation and GRP78 reduction in hippocampus.•High glucose induced astrocytic activation in C6 cells.•High glucose…”
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Photodynamic effect of curcumin on NPC/CNE2 cells
Published in Journal of environmental pathology, toxicology and oncology (2006)“…Nasopharyngeal carcinoma (NPC) is highly prevalent in Southern China. Radiotherapy is the primary treatment of NPC, but the rate of tumor recurrence is…”
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Danshen prevents the occurrence of oxidative stress in the eye and aorta of diabetic rats without affecting the hyperglycemic state
Published in Journal of ethnopharmacology (15-06-2006)“…Oxidative stress has been implicated in the pathogenesis of diabetic complications. We have previously demonstrated the occurrence of oxidative stress in the…”
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Alterations in antioxidant enzyme activities in the eyes, aorta and kidneys of diabetic rats relevant to the onset of oxidative stress
Published in Life sciences (1973) (01-07-2005)“…Profound changes in antioxidant enzyme activities were observed in a number of vascular tissues during the development of streptozotocin-induced diabetes in…”
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Potential biomarkers found by protein profiling may provide insight for the macrovascular pathogenesis of diabetes mellitus
Published in Disease markers (2006)“…Diabetes mellitus (DM) is an alarming threat to health of mankind, yet its pathogenesis is unclear. The purpose of this study was to find potential biomarkers…”
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Changing pattern of desmocollin 3 expression accompanies epidermal organisation during skin development
Published in Developmental dynamics (01-11-1997)“…The adhesive core of the desmosome is composed of cadherin‐like glycoproteins of 2 families, desmocollins and desmogleins. The desmosomal cadherins show…”
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A Case of Pemphigus Vulgaris Showing Reactivity with Pemphigus Antigens (Dsg1 and Dsg3) and Desmocollins
Published in Journal of investigative dermatology (01-04-1995)“…Both pemphigus vulgaris antigen (PVA; Dsg3) and pemphigus foliaceus antigen (PFA; Dsg1) are members of the desmoglein subfamily of the cadherin supergene…”
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