Search Results - "Yue, Jessica"

Insulin Signals Through the Dorsal Vagal Complex to Regulate Energy Balance by FILIPPI, Beatrice M, BASSIRI, Aria, ABRAHAM, Mona A, DUCA, Frank A, YUE, Jessica T. Y, LAM, Tony K. T

“…Insulin signaling in the hypothalamus regulates food intake and hepatic glucose production in rodents. Although it is known that insulin also activates insulin…”
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Silencing gut CCK cells alters gut reaction to sugar by Yue, Jessica T. Y., Duca, Frank A., Lam, Tony K. T.

“…The duodenum distinguishes between sugar and sweeteners, but the cells involved in this process remain elusive. Buchanan and colleagues engineered a flexible…”
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Fatty acid sensing in the gut and the hypothalamus: In vivo and in vitro perspectives by Duca, Frank A., Yue, Jessica T.Y.

“…•Fatty acid sensing in the gut and brain regulates energy and glucose homeostasis.•Lipids activate a gut–brain axis to lower food intake and glucose…”
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Glycine Normalizes Hepatic Triglyceride-Rich VLDL Secretion by Triggering the CNS in High-Fat Fed Rats by Yue, Jessica T.Y, Mighiu, Patricia I, Naples, Mark, Adeli, Khosrow, Lam, Tony K.T

“…RATIONALE:Dysregulation of hepatic triglyceride (TG)-rich very low-density lipoproteins (VLDL-TG) in obesity and type 2 diabetes contributes to the…”
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Lipid Sensing and Insulin Resistance in the Brain by Yue, Jessica T.Y., Lam, Tony K.T.

“…Lipid sensing and insulin signaling in the brain independently triggers a negative feedback system to lower glucose production and food intake. Here, we…”
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Somatostatin Receptor Type 2 Antagonism Improves Glucagon and Corticosterone Counterregulatory Responses to Hypoglycemia in Streptozotocin-Induced Diabetic Rats by YUE, Jessica T. Y, BURDETT, Elena, COY, David H, GIACCA, Adria, EFENDIC, Suad, VRANIC, Mladen

“…Diminished responsiveness to hypoglycemia contributes to defective counterregulation in diabetes. Pancreatic and/or circulating somatostatin are elevated in…”
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Antiobesogenic effects of central GIPR antagonism by Yue, Jessica T Y, Lam, Tony K T

“…Developing effective treatments for obesity and related metabolic disease remains a challenge. One logical strategy targets the appetite-regulating actions of…”
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246-LB: Stimulation of Hepatic Lipid Secretion by Glucocorticoid Action in the Nucleus of the Solitary Tract by VASILEV, BOYAN, GREWAL, MANTASH S., LUM, BRYAN, YUE, JESSICA T.

“…Dysregulated lipid metabolism is a characteristic of diabetes, insulin resistance, and obesity. Increased glucocorticoid (GC) levels and/or action is…”
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A glucose-sensing mechanism with glucose transporter 1 and pyruvate kinase in the area postrema regulates hepatic glucose production in rats by Li, Rosa J.W., Chiu, Jennifer F.M., Bruce, Kyla, Zhang, Song-Yang, Barros, Daniel R., Yue, Jessica T.Y., Lam, Tony K.T.

“…The area postrema (AP) of the brain is exposed to circulating metabolites and hormones. However, whether AP detects glucose changes to exert biological…”
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Hypothalamic glucagon signaling inhibits hepatic glucose production by Mighiu, Patricia I, Yue, Jessica T Y, Filippi, Beatrice M, Abraham, Mona A, Chari, Madhu, Lam, Carol K L, Yang, Clair S, Christian, Nikita R, Charron, Maureen J, Lam, Tony K T

“…Glucagon has traditionally been thought to act exclusively on the liver to promote endogenous glucose production in that organ. Tony Lam and his colleagues now…”
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245-LB: Glucagon Infusion into the Mediobasal Hypothalamus Lowers Hepatic Triglyceride Secretion by GREWAL, MANTASH S., VASILEV, BOYAN, SOLTYS, CARRIE-LYNN M., LUM, BRYAN, YUE, JESSICA T.

“…Diabetes and obesity are associated with dysregulated liver lipid metabolism. Glucagon has an essential role in lipid metabolism, in addition to regulating…”
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1307-P: Leptin Action in the Nucleus of the Solitary Tract by BRUCE, KYLA, LI, ROSA J.W., LIM, YUMI, YUE, JESSICA T., LAM, TONY K.

“…Obesity and diabetes are characterized by a disruption in energy balance and glucose homeostasis in association with leptin resistance. Leptin action in the…”
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104-OR: Glucoregulatory Effects of Hypothalamic Glucocorticoid Action In Vivo by BEAULIEU-BAYNE, EMILIE, CARDOSO, MIGUEL, KIM, HYEJUN, YANG, SHULING, YUE, JESSICA T.

“…Diabetes is characterized by dysregulated glucose homeostasis that leads to hyperglycemia, due in part to increased hepatic glucose production (GP) and insulin…”
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Amelioration of Hypoglycemia Via Somatostatin Receptor Type 2 Antagonism in Recurrently Hypoglycemic Diabetic Rats by YUE, Jessica T. Y, RIDDELL, Michael C, BURDETT, Elena, COY, David H, EFENDIC, Suad, VRANIC, Mladen

“…Selective antagonism of somatostatin receptor type 2 (SSTR2) normalizes glucagon and corticosterone responses to hypoglycemic clamp in diabetic rats. The…”
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Inhibition of glycine transporter-1 in the dorsal vagal complex improves metabolic homeostasis in diabetes and obesity by Yue, Jessica T. Y., Abraham, Mona A., Bauer, Paige V., LaPierre, Mary P., Wang, Peili, Duca, Frank A., Filippi, Beatrice M., Chan, Owen, Lam, Tony K. T.

“…Impaired glucose homeostasis and energy balance are integral to the pathophysiology of diabetes and obesity. Here we show that administration of a glycine…”
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An Egg White-Derived Peptide Enhances Systemic Insulin Sensitivity and Modulates Markers of Non-Alcoholic Fatty Liver Disease in Obese, Insulin Resistant Mice by de Campos Zani, Stepheny C, Wang, Ren, Veida-Silva, Hellen, Clugston, Robin D, Yue, Jessica T Y, Mori, Marcelo A, Wu, Jianping, Chan, Catherine B

“…Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic syndrome, is a global health problem. Currently, no pharmacological…”
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Mental health and psychosocial support programmes for displaced populations in low- and middle-income countries (LMICs): A systematic review of process, perspectives and experiences by Dickson, Kelly, Ko, Sum Yue (Jessica), Nguyen, Celine, Minchenko, Dayana, Bangpan, Mukdarut

“…Displacement exerts an ongoing negative impact on people’s mental health. The majority of displaced populations are hosted in the global south, yet there is a…”
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44-LB: Hypothalamic Glucocorticoid Action Regulates Lipid Metabolism by CARDOSO, MIGUEL, WANG, MARK, LING, EMILY, LEE, HONGJU (JENNIFER), BEAULIEU-BAYNE, EMILIE, YUE, JESSICA T.

“…Aberrant lipid homeostasis is a feature of diabetes and obesity. This metabolic imbalance is associated with excessive levels and/or actions of glucocorticoids…”
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A fatty acid-dependent hypothalamic–DVC neurocircuitry that regulates hepatic secretion of triglyceride-rich lipoproteins by Yue, Jessica T. Y., Abraham, Mona A., LaPierre, Mary P., Mighiu, Patricia I., Light, Peter E., Filippi, Beatrice M., Lam, Tony K. T.

“…The brain emerges as a regulator of hepatic triglyceride-rich very-low-density lipoproteins (VLDL-TG). The neurocircuitry involved as well as the ability of…”
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Glucagon and lipid signaling in the hypothalamus by LaPierre, Mary P, Abraham, Mona A, Filippi, Beatrice M, Yue, Jessica T. Y, Lam, Tony K. T

“…Hyperglycemia, caused in part by elevated hepatic glucose production (GP), is a hallmark feature of diabetes and obesity. The hypothalamus responds to hormones…”
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