Search Results - "Yuanqing Lu"

Potential Significance of Circular RNA in Human Placental Tissue for Patients with Preeclampsia by Qian, Yating, Lu, Yuanqing, Rui, Can, Qian, Yujia, Cai, Manhong, Jia, Ruizhe

“…Aims: This study aimed to identify the different expression of circular RNAs (circRNAs) in the placental tissues of pregnant women with preeclampsia (PE) and…”
Get full text

Distinct immune responses to transgene products from rAAV1 and rAAV8 vectors by Lu, Yuanqing, Song, Sihong

“…Recently developed serotypes of recombinant adeno-associated virus (rAAV) vectors have significantly enhanced the use of rAAV vectors for gene therapy…”
Get full text

Alpha-defensins inhibit ERK/STAT3 signaling during monocyte-macrophage differentiation and impede macrophage function by Lee, Jungnam, Mohammad, Naweed, Lu, Yuanqing, Oshins, Regina, Aranyos, Alek, Brantly, Mark

“…Alpha-1-antitrypsin deficiency (AATD) is a genetic disorder associated with a 5-tenfold decrease in lung levels of alpha-1-antitrypsin (AAT) and an increased…”
Get full text

Berberine potentiates liver inflammation and fibrosis in the PIZ hAAT transgenic murine model by Lu, Yuanqing, Mohammad, Naweed S, Lee, Jungnam, Aranyos, Alek M, Serban, Karina A, Brantly, Mark L

“…Alpha-1 antitrypsin deficiency (AATD) is an inherited disease, the common variant caused by a Pi*Z mutation in the SERPINA1 gene. Pi*Z AAT increases the risk…”
Get full text

High concentration of coagulase-negative staphylococci carriage among bioaerosols of henhouses in Central China by Lu, Yuanqing, Lu, Qin, Cheng, Yiluo, Wen, Guoyuan, Luo, Qingping, Shao, Huabin, Zhang, Tengfei

“…Coagulase-negative staphylococci (CoNS) are a group of opportunistic pathogens, which are widely spread in the environment. Animal breeding is an important…”
Get full text

Erdj3 Has an Essential Role for Z Variant Alpha‐1‐Antitrypsin Degradation by Khodayari, Nazli, Marek, George, Lu, Yuanqing, Krotova, Karina, Wang, Rejean Liqun, Brantly, Mark

“…ABSTRACT Alpha‐1‐antitrypsin deficiency (AATD) is an inherited disease characterized by emphysema and liver disease. AATD is most often caused by a single…”
Get full text

The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease by Khodayari, Nazli, Wang, Rejean L, Oshins, Regina, Lu, Yuanqing, Millett, Michael, Aranyos, Alek M, Mostofizadeh, Sayedamin, Scindia, Yogesh, Flagg, Tammy O, Brantly, Mark

“…Alpha-1 antitrypsin deficiency (AATD) is caused by a single mutation in the SERPINA1 gene, which culminates in the accumulation of misfolded alpha-1…”
Get full text

Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus by Elshikha, Ahmed S, Lu, Yuanqing, Chen, Mong-Jen, Akbar, Mohammad, Zeumer, Leilani, Ritter, Andrea, Elghamry, Hanaa, Mahdi, Mahmoud A, Morel, Laurence, Song, Sihong

“…Systemic lupus erythematosus (SLE) is an autoimmune disorder with a worldwide distribution and considerable mortality and morbidity. Although the pathogenesis…”
Get full text

Comparative Proteomic Profile of the Human Umbilical Cord Blood Exosomes between Normal and Preeclampsia Pregnancies with High-Resolution Mass Spectrometry by Jia, Ruizhe, Li, Jingyun, Rui, Can, Ji, Hui, Ding, Hongjuan, Lu, Yuanqing, De, Wei, Sun, Lizhou

“…Background/Aims: Exosomes are extracellular vesicles that are involved in several biological processes. The roles of proteins from human umbilical cord blood…”
Get full text

Alpha 1 Antitrypsin-Deficient Macrophages Have Impaired Efferocytosis of Apoptotic Neutrophils by Lee, Jungnam, Lu, Yuanqing, Oshins, Regina, West, Jesse, Moneypenny, Craig G, Han, Kyudong, Brantly, Mark L

“…Alpha 1 antitrypsin deficiency (AATD) is an autosomal co-dominant disorder characterized by a low level of circulating AAT, which significantly reduces…”
Get full text

α1-Antitrypsin Protects β-Cells From Apoptosis by BIN ZHANG, YUANQING LU, CAMPBELL-THOMPSON, Martha, SPENCER, Terry, WASSERFALL, Clive, ATKINSON, Mark, SIHONG SONG

“…α1-Antitrypsin Protects β-Cells From Apoptosis Bin Zhang 1 , Yuanqing Lu 1 , Martha Campbell-Thompson 2 , Terry Spencer 3 , Clive Wasserfall 2 , Mark Atkinson…”
Get full text

Alu RNA induces NLRP3 expression through TLR7 activation in α-1-antitrypsin–deficient macrophages by Lee, Jungnam, Mohammad, Naweed, Lu, Yuanqing, Kang, Keunsoo, Han, Kyudong, Brantly, Mark

“…α-1 antitrypsin (AAT) is a serine protease inhibitor that plays a pivotal role in maintaining lung homeostasis. The most common AAT allele associated with AAT…”
Get full text

Peptidome Analysis of Human Serum From Normal and Preeclamptic Pregnancies by Dai, Xiaonan, Song, Xuejing, Rui, Can, Meng, Li, Xue, Xuan, Ding, Hongjuan, Shen, Rong, Li, Jun, Li, Jingyun, Lu, Yuanqing, Long, Wei

“…ABSTRACT Preeclampsia is a kind of disease that severely harms the health of pregnant women and infants. To better understand the molecular mechanisms involved…”
Get full text

Adipose tissue-derived mesenchymal stem cell-based liver gene delivery by Li, Hong, Zhang, Bin, Lu, Yuanqing, Jorgensen, Marda, Petersen, Bryon, Song, Sihong

“…Background & Aims The adipose tissue represents an accessible, abundant, and replenishable source of adult stem cells for potential applications in…”
Get full text

The unfolded protein response to PIZ alpha‐1 antitrypsin in human hepatocellular and murine models by Lu, Yuanqing, Wang, Liqun R., Lee, Jungnam, Mohammad, Naweed S., Aranyos, Alek M., Gould, Calvin, Khodayari, Nazli, Oshins, Regina A., Moneypenny, Craig G., Brantly, Mark L.

“…Alpha‐1 antitrypsin (AAT) deficiency (AATD) is an inherited disease caused by mutations in the serpin family A member 1 (SERPINA1, also known as AAT) gene. The…”
Get full text

In Situ Transplantation of Alginate Bioencapsulated Adipose Tissues Derived Stem Cells (ADSCs) via Hepatic Injection in a Mouse Model by Chen, Mong-Jen, Lu, Yuanqing, Simpson, Nicholas E, Beveridge, Mark J, Elshikha, Ahmed S, Akbar, Mohammad Ahsanul, Tsai, Hsin-Yin, Hinske, Stephanie, Qin, Junling, Grunwitz, Christian R, Chen, Tina, Brantly, Mark L, Song, Sihong

“…Adipose tissue derived stem cells (ADSCs) transplantation has recently gained widespread enthusiasm, particularly in the perspective to use them as potential…”
Get full text

Alpha 1 Antitrypsin Gene Therapy Extends the Lifespan of Lupus-Prone Mice by Elshikha, Ahmed Samir, Yuan, Ye, Lu, Yuanqing, Chen, Mong-Jen, Abboud, Georges, Akbar, Mohammad Ahsanul, Plate, Henrike, Wolney, Hedwig, Hoffmann, Tanja, Tagari, Eleni, Zeumer, Leilani, Morel, Laurence, Song, Sihong

“…Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by high levels of pathogenic autoantibodies and tissue damage. Multiple…”
Get full text

Research and Design of A Land Reclamation Supervisory Information System in A Mining Area by Guo, Xiaozhong, Jian Pan, Ganguo Wu, Fanxiu Xue, Yuanqing Lu

“…Using an overall document data comprehensive analysis system and a structure analysis, this study preliminarily classified technical indicators, structured the…”
Get full text

Alpha 1-Antitrypsin Therapy Mitigated Ischemic Stroke Damage in Rats by Moldthan, Huong L., PhD, Hirko, Aaron C., PhD, Thinschmidt, Jeffrey S., MSc, Grant, Maria B., MD, Li, Zhimin, PhD, Peris, Joanna, PhD, Lu, Yuanqing, MD, Elshikha, Ahmed S., MSc, King, Michael A., PhD, Hughes, Jeffrey A., PharmD, PhD, Song, Sihong, PhD

“…Our objective is to develop a new therapy for the treatment of stroke. Currently, the only effective therapy for acute ischemic stroke is the thrombolytic…”
Get full text

DNA-Dependent PK Inhibits Adeno-Associated Virus DNA Integration by Song, Sihong, Lu, Yuanqing, Choi, Young-Kook, Han, Yinong, Tang, Qiushi, Zhao, Ge, Berns, Kenneth I., Flotte, Terence R.

“…Recent studies have shown that recombinant adeno-associated virus (rAAV) can persist in episomal form; however, factors affecting rAAV persistence are poorly…”
Get full text