Search Results - "Yuan, Weitang"
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Effect of exosomal miRNA on cancer biology and clinical applications
Published in Molecular cancer (11-10-2018)“…Exosomes, extracellular vesicles with diameters ranging from 30 to 150 nm, are widely present in various body fluids. Recently, microRNAs (miRNAs) have been…”
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Roles of RNA Methylation on Tumor Immunity and Clinical Implications
Published in Frontiers in immunology (10-03-2021)“…RNA methylation is a kind of RNA modification that exists widely in eukaryotes and prokaryotes. RNA methylation occurs not only in mRNA but also in ncRNA…”
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3
The interplay between m6A RNA methylation and noncoding RNA in cancer
Published in Journal of hematology and oncology (22-11-2019)“…N6-methyladenosine (m6A) methylation, one of the most common RNA modifications, has been reported to execute important functions that affect normal life…”
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The role of N6-methyladenosine (m6A) modification in the regulation of circRNAs
Published in Molecular cancer (10-06-2020)“…Abstract N 6 -methyladenosine (m 6 A), the most abundant modification in eukaryotic cells, regulates RNA transcription, processing, splicing, degradation, and…”
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Exosomal circRNAs: biogenesis, effect and application in human diseases
Published in Molecular cancer (05-07-2019)“…Exosomes have emerged as critical mediators of intercellular communication, both locally and systemically, by regulating a diverse range of biological…”
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Roles of circRNAs in the tumour microenvironment
Published in Molecular cancer (23-01-2020)“…The tumour microenvironment (TME) constitutes the area surrounding the tumour during its development and has been demonstrated to play roles in cancer-related…”
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Roles of tumor-associated macrophages in anti-PD-1/PD-L1 immunotherapy for solid cancers
Published in Molecular cancer (21-03-2023)“…In recent years, tumor immunotherapy has made significant progress. However, tumor immunotherapy, particularly immune checkpoint inhibitors (e.g., PD-1/PD-L1…”
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Effects of exosomes on pre-metastatic niche formation in tumors
Published in Molecular cancer (11-03-2019)“…A pre-metastatic niche is a microenvironment prepared for the colonization of circulating tumor cells in specific organs. Exosomes are extracellular vesicles…”
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Emerging role of exosome-derived long non-coding RNAs in tumor microenvironment
Published in Molecular cancer (20-04-2018)“…Exosomes are extracellular vesicles released by many cell types and have been attributed for their roles in many diseases including cancer. Exosomes secreted…”
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LncRna CPS1-IT1 Suppresses Cell Proliferation, Invasion and Metastasis in Colorectal Cancer
Published in Cellular physiology and biochemistry (01-12-2017)“…Background/Aims: Increasing evidence demonstrates that long non-coding RNAs (lncRNAs) regulate diverse cellular processes and cancer progression. Whether…”
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11
Oncogenic driver genes and tumor microenvironment determine the type of liver cancer
Published in Cell death & disease (04-05-2020)“…Primary liver cancer (PLC) may be mainly classified as the following four types: hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC),…”
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Effects of RNA methylation on Tumor angiogenesis and cancer progression
Published in Molecular cancer (06-12-2023)“…Tumor angiogenesis plays vital roles in the growth and metastasis of cancer. RNA methylation is one of the most common modifications and is widely observed in…”
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Exosomal Noncoding RNAs and Tumor Drug Resistance
Published in Cancer research (Chicago, Ill.) (15-10-2020)“…Tumor drug resistance is a major challenge in the treatment of cancer. Noncoding RNAs (ncRNA) play a role in the progression of drug resistance. Recent studies…”
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Roles of the Exosomes Derived From Myeloid-Derived Suppressor Cells in Tumor Immunity and Cancer Progression
Published in Frontiers in immunology (27-01-2022)“…Tumor immunity is involved in malignant tumor progression. Myeloid-derived suppressor cells (MDSCs) play an irreplaceable role in tumor immunity. MDSCs are…”
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Advances in Engineered Macrophages: A New Frontier in Cancer Immunotherapy
Published in Cell death & disease (01-04-2024)“…Macrophages, as pivotal cells within the tumour microenvironment, significantly influence the impact of and reactions to treatments for solid tumours. The…”
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MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis
Published in Journal of experimental & clinical cancer research (20-11-2020)“…Abstract Background Glycolysis plays an essential role in the growth and metastasis of solid cancer and has received increasing attention in recent years…”
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Colorectal cancer cell-derived CCL20 recruits regulatory T cells to promote chemoresistance via FOXO1/CEBPB/NF-κB signaling
Published in Journal for immunotherapy of cancer (08-08-2019)“…Colorectal cancer (CRC) is one of the most common forms of cancer worldwide. The tumor microenvironment plays a key role in promoting the occurrence of…”
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Exosome-derived noncoding RNAs: Function, mechanism, and application in tumor angiogenesis
Published in Molecular therapy. Nucleic acids (08-03-2022)“…Exosomes are extracellular vesicles released by various cell types that perform various biological functions, mainly mediating communication between different…”
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Pathogenesis and Mechanism of Gastrointestinal Infection With COVID-19
Published in Frontiers in immunology (10-11-2021)“…As a new infectious disease, COVID-19 is spread through the respiratory tract in most cases. Its source and pathological mechanism are not clear. The most…”
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Th17 cells inhibit CD8 + T cell migration by systematically downregulating CXCR3 expression via IL-17A/STAT3 in advanced-stage colorectal cancer patients
Published in Journal of hematology and oncology (05-06-2020)“…CD8 T cell trafficking to the tumor site is essential for effective colorectal cancer (CRC) immunotherapy. However, the mechanism underlying CD8 T cell…”
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