Search Results - "Yuan, Weien"
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An integrated multi-layer 3D-fabrication of PDA/RGD coated graphene loaded PCL nanoscaffold for peripheral nerve restoration
Published in Nature communications (22-01-2018)“…As a conductive nanomaterial, graphene has huge potentials in nerve function restoration by promoting electrical signal transduction and metabolic activities…”
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An Overview of Pickering Emulsions: Solid-Particle Materials, Classification, Morphology, and Applications
Published in Frontiers in pharmacology (23-05-2017)“…Pickering emulsion, a kind of emulsion stabilized only by solid particles locating at oil-water interface, has been discovered a century ago, while being…”
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Rationale and Application of PEGylated Lipid-Based System for Advanced Target Delivery of siRNA
Published in Frontiers in pharmacology (20-01-2021)“…RNA interference (RNAi) technology has become a powerful tool in application of unraveling the mechanism of disease and may hold the potential to be developed…”
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Potential Value of miR-221/222 as Diagnostic, Prognostic, and Therapeutic Biomarkers for Diseases
Published in Frontiers in immunology (16-02-2017)“…microRNAs (miRNAs) are short non-coding RNAs that regulate gene expression by base pairing with their target messenger RNAs. Dysregulation of miRNAs is…”
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Insights into medical humanities education in China and the West
Published in Journal of International Medical Research (01-09-2018)“…Medical humanity is the soul of health education. Beginning medical students are taught various aspects of basic medicine, such as biochemistry, anatomy, and…”
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Advances in Roles of miR-132 in the Nervous System
Published in Frontiers in pharmacology (25-10-2017)“…miR-132 is an endogenous small RNA and controls post-transcriptional regulation of gene expression via controlled degradation of mRNA or transcription…”
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Diclofenac Resensitizes Methicillin‐Resistant Staphylococcus aureus to β‐Lactams and Prevents Implant Infections
Published in Advanced science (01-07-2021)“…Implant infections caused by methicillin‐resistant Staphylococcus aureus (MRSA) can cause major complications during the perioperative period. Diclofenac, one…”
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Freeze-Drying Formulations Increased the Adenovirus and Poxvirus Vaccine Storage Times and Antigen Stabilities
Published in Virologica Sinica (01-06-2021)“…Successful vaccines induce specific immune responses and protect against various viral and bacterial infections. Noninactivated vaccines, especially viral…”
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Platelet-Rich Plasma Derived Growth Factors Contribute to Stem Cell Differentiation in Musculoskeletal Regeneration
Published in Frontiers in chemistry (31-10-2017)“…Stem cell treatment and platelet-rich plasma (PRP) therapy are two significant issues in regenerative medicine. Stem cells such as bone marrow mesenchymal stem…”
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Polyvinyl Alcohol/Chitosan/Polyhexamethylene Biguanide Phase Separation System: A Potential Topical Antibacterial Formulation with Enhanced Antimicrobial Effect
Published in Molecules (Basel, Switzerland) (15-03-2020)“…An aqueous polyvinyl alcohol (PVA)/chitosan (CHT)/polyhexamethylene biguanide (PHMB) blends (PVA/CHT/PHMB blends) has been developed as a potential low dose…”
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Biomaterial-based regenerative therapeutic strategies for spinal cord injury
Published in NPG Asia materials (19-01-2024)“…As one of the most intractable neurological diseases, spinal cord injury (SCI) often leads to permanent neurological impairment in patients. Unfortunately, due…”
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Lipopolyplex for Therapeutic Gene Delivery and Its Application for the Treatment of Parkinson's Disease
Published in Frontiers in aging neuroscience (05-04-2016)“…Lipopolyplex is a core-shell structure composed of nucleic acid, polycation and lipid. As a non-viral gene delivery vector, lipopolyplex combining the…”
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Progress of electrospun fibers as nerve conduits for neural tissue repair
Published in Nanomedicine (London, England) (01-08-2014)“…Nerve tissue regeneration approaches have gained much attention in recent years, and nerve conduits (NCs), which facilitate nerve tissue regeneration, have…”
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14
Polymersomes of asymmetric bilayer membrane formed by phase-guided assembly
Published in Journal of controlled release (01-11-2010)“…Encapsulating delicate biomolecules into submicron-sized polymer particulate systems with preserved native conformation and sufficient loading efficiency is of…”
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Polymerizing Pyrrole Coated Poly (l-lactic acid-co-ε-caprolactone) (PLCL) Conductive Nanofibrous Conduit Combined with Electric Stimulation for Long-Range Peripheral Nerve Regeneration
Published in Frontiers in molecular neuroscience (08-11-2016)“…Electrospinning and electric stimulation (ES) are both promising methods to support neuron adhesion and guide extension of neurons for nerve regeneration…”
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Autologous erythrocytes delivery of berberine hydrochloride with long-acting effect for hypolipidemia treatment
Published in Drug delivery (01-01-2020)“…Discovery of novel pharmacological effects of berberine hydrochloride (BH) has made its clinical application valuable. However, further development and…”
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Hydrogel Microneedle Arrays for Transdermal Drug Delivery
Published in Nano-micro letters (01-07-2014)“…Stratum corneum is the main obstacle for drugs to pass through the skin. Microneedles are composed of arrays of micro-projections formed with different…”
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Felodipine enhances aminoglycosides efficacy against implant infections caused by methicillin-resistant Staphylococcus aureus, persisters and biofilms
Published in Bioactive materials (01-08-2022)“…Methicillin-resistant Staphylococcus aureus (MRSA), biofilms, and persisters are three major factors leading to recurrent and recalcitrant implant infections…”
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Improving Bone Regeneration Using Chordin siRNA Delivered by pH-Responsive and Non-Toxic Polyspermine Imidazole-4,5-Imine
Published in Cellular physiology and biochemistry (01-04-2018)“…Background/Aims: Bone nonunion remains a challenge for orthopaedists. The technological advancements that have been made in precisely silencing target genes…”
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Osteoinductivity and Antibacterial Properties of Strontium Ranelate-Loaded Poly(Lactic-co-Glycolic Acid) Microspheres With Assembled Silver and Hydroxyapatite Nanoparticles
Published in Frontiers in pharmacology (18-04-2018)“…Bone-related infection rates are 4-64% in long open bone fractures and nearly 1% in joint-related surgeries. Treating bone infections and infection-related…”
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