Search Results - "Yuan, Shaopeng"

Inflammatory memory sensitizes skin epithelial stem cells to tissue damage by Naik, Shruti, Larsen, Samantha B., Gomez, Nicholas C., Alaverdyan, Kirill, Sendoel, Ataman, Yuan, Shaopeng, Polak, Lisa, Kulukian, Anita, Chai, Sophia, Fuchs, Elaine

“…The skin barrier is the body’s first line of defence against environmental assaults, and is maintained by epithelial stem cells (EpSCs). Despite the…”
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Comprehensive assessment of miniature CRISPR-Cas12f nucleases for gene disruption by Xin, Changchang, Yin, Jianhang, Yuan, Shaopeng, Ou, Liqiong, Liu, Mengzhu, Zhang, Weiwei, Hu, Jiazhi

“…Because of their small size, the recently developed CRISPR-Cas12f nucleases can be effectively packaged into adeno-associated viruses for gene therapy…”
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Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma by Lachowicz-Scroggins, Marrah E, Yuan, Shaopeng, Kerr, Sheena C, Dunican, Eleanor M, Yu, Michelle, Carrington, Stephen D, Fahy, John V

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Roles of epithelial cell-derived periostin in TGF-β activation, collagen production, and collagen gel elasticity in asthma by Sidhu, Sukhvinder S., Yuan, Shaopeng, Innes, Anh L., Kerr, Sheena, Woodruff, Prescott G., Hou, Lydia, Muller, Susan J., Fahy, John V., Yamamoto, Keith R.

“…Periostin is considered to be a matricellular protein with expression typically confined to cells of mesenchymal origin. Here, by using in situ hybridization,…”
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Stem cells repurpose proliferation to contain a breach in their niche barrier by Lay, Kenneth, Yuan, Shaopeng, Gur-Cohen, Shiri, Miao, Yuxuan, Han, Tianxiao, Naik, Shruti, Pasolli, H Amalia, Larsen, Samantha B, Fuchs, Elaine

“…Adult stem cells are responsible for life-long tissue maintenance. They reside in and interact with specialized tissue microenvironments (niches). Using murine…”
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Oxidation increases mucin polymer cross-links to stiffen airway mucus gels by Yuan, Shaopeng, Hollinger, Martin, Lachowicz-Scroggins, Marrah E, Kerr, Sheena C, Dunican, Eleanor M, Daniel, Brian M, Ghosh, Sudakshina, Erzurum, Serpel C, Willard, Belinda, Hazen, Stanley L, Huang, Xiaozhu, Carrington, Stephen D, Oscarson, Stefan, Fahy, John V

“…Airway mucus in cystic fibrosis (CF) is highly elastic, but the mechanism behind this pathology is unclear. We hypothesized that the biophysical properties of…”
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Pulmonary Vascular Destabilization in the Premetastatic Phase Facilitates Lung Metastasis by Huang, Yujie, Song, Nan, Ding, Yanping, Yuan, Shaopeng, Li, Xuhui, Cai, Hongchen, Shi, Hubing, Luo, Yongzhang

“…Before metastasis, certain organs have already been influenced by primary tumors. However, the exact alterations and regulatory mechanisms of the premetastatic…”
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Alternative splicing of interleukin-33 and type 2 inflammation in asthma by Gordon, Erin D., Simpson, Laura J., Rios, Cydney L., Ringel, Lando, Lachowicz-Scroggins, Marrah E., Peters, Michael C., Wesolowska-Andersen, Agata, Gonzalez, Jeanmarie R., MacLeod, Hannah J., Christian, Laura S., Yuan, Shaopeng, Barry, Liam, Woodruff, Prescott G., Ansel, K. Mark, Nocka, Karl, Seibold, Max A., Fahy, John V.

“…Type 2 inflammation occurs in a large subgroup of asthmatics, and novel cytokine-directed therapies are being developed to treat this population. In mouse…”
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Novel Nitric Oxide-Releasing Derivatives of Brusatol as Anti-Inflammatory Agents: Design, Synthesis, Biological Evaluation, and Nitric Oxide Release Studies by Tang, Weibin, Xie, Jianlin, Xu, Song, Lv, Haining, Lin, Mingbao, Yuan, Shaopeng, Bai, Jinye, Hou, Qi, Yu, Shishan

“…Brusatol, a biologically active natural product, was modified in four distinct positions through the covalent attachment of a furoxan moiety, which acts as a…”
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Transfer of mitochondrial DNA into the nuclear genome during induced DNA breaks by Wu, Jinchun, Liu, Yang, Ou, Liqiong, Gan, Tingting, Zhangding, Zhengrong, Yuan, Shaopeng, Liu, Xinyi, Liu, Mengzhu, Li, Jiasheng, Yin, Jianhang, Xin, Changchang, Tian, Ye, Hu, Jiazhi

“…Mitochondria serve as the cellular powerhouse, and their distinct DNA makes them a prospective target for gene editing to treat genetic disorders. However, the…”
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Safeguarding genome integrity during gene-editing therapy in a mouse model of age-related macular degeneration by Yin, Jianhang, Fang, Kailun, Gao, Yanxia, Ou, Liqiong, Yuan, Shaopeng, Xin, Changchang, Wu, Weiwei, Wu, Wei-wei, Hong, Jiaxu, Yang, Hui, Hu, Jiazhi

“…Ensuring genome safety during gene editing is crucial for clinical translation of the high-efficient CRISPR-Cas9 toolbox. Therefore, the undesired events…”
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Lignans and Neolignans from Sinocalamus affinis and Their Absolute Configurations by Xiong, Liang, Zhu, Chenggeng, Li, Yanru, Tian, Ye, Lin, Sheng, Yuan, Shaopeng, Hu, Jinfeng, Hou, Qi, Chen, Naihong, Yang, Yongchun, Shi, Jiangong

“…Twenty-two new lignans and neolignans (1−22), together with 14 known analogues, have been isolated from an ethanolic extract of the stem (with skin removed) of…”
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Interleukin-17 Stimulates STAT3-Mediated Endothelial Cell Activation for Neutrophil Recruitment by Yuan, Shaopeng, Zhang, Shimeng, Zhuang, Yuanyuan, Zhang, He, Bai, Jinye, Hou, Qi

“…Background/Aims: Interleukin-17 (IL-17) is a major pro-inflammatory cytokine that initiates and maintains inflammation. However, the molecular mechanisms as to…”
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Overexpression of Platelet-Derived Growth Factor-BB Increases Tumor Pericyte Content via Stromal-Derived Factor-1 α/CXCR4 Axis by Song, Nan, Huang, Yujie, Shi, Hubing, Yuan, Shaopeng, Ding, Yanping, Song, Xiaomin, Fu, Yan, Luo, Yongzhang

“…Abstract Platelet-derived growth factor-BB (PDGF-BB) is a well-characterized growth factor displaying potent biological effects on angiogenesis. Recent studies…”
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Size-Dependent Toxicity of Nano-C60 Aggregates: More Sensitive Indication by Apoptosis-Related Bax Translocation in Cultured Human Cells by Song, Maoyong, Yuan, Shaopeng, Yin, Junfa, Wang, Xiaoli, Meng, Zihui, Wang, Hailin, Jiang, Guibin

“…The toxicity of NPs is not well characterized in terms of their size. In particular, the size-based toxicity of fullerene (C60) remains an issue because of a…”
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ITGB5 mutation discovered in a Chinese family with blepharophimosis-ptosis-epicanthus inversus syndrome by Cheng, Tianling, Yuan, Xiaobin, Yuan, Shaopeng, Zhu, Jianying, Tang, Shengjian, Zhang, Yujie

“…Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) is a rare autosomal-dominant genetic disorder, and mutations in the forkhead box L2 ( ) gene are…”
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The angiogenic function of nucleolin is mediated by vascular endothelial growth factor and nonmuscle myosin by Huang, Yujie, Shi, Hubing, Zhou, Hao, Song, Xiaomin, Yuan, Shaopeng, Luo, Yongzhang

“…Nucleolin, originally described as a nuclear protein, was recently found to be expressed on the surface of endothelial cells during angiogenic. However, the…”
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FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection by Kerr, Sheena C, Fischer, Gregory J, Sinha, Meenal, McCabe, Orla, Palmer, Jonathan M, Choera, Tsokyi, Lim, Fang Yun, Wimmerova, Michaela, Carrington, Stephen D, Yuan, Shaopeng, Lowell, Clifford A, Oscarson, Stefan, Keller, Nancy P, Fahy, John V

“…The immune mechanisms that recognize inhaled Aspergillus fumigatus conidia to promote their elimination from the lungs are incompletely understood. FleA is a…”
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Study of cytotoxic effects of single-walled carbon nanotubes functionalized with different chemical groups on human MCF7 cells by Song, Maoyong, Zeng, Luzhe, Yuan, Shaopeng, Yin, Junfa, Wang, Hailin, Jiang, Guibin

“…[Display omitted] •Different functionalized chemical groups affect the dispersibility of f-SWCNTs.•Insignificant effects on mitochondrial activity and ROS…”
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Author Correction: Inflammatory memory sensitizes skin epithelial stem cells to tissue damage by Naik, Shruti, Larsen, Samantha B., Gomez, Nicholas C., Alaverdyan, Kirill, Sendoel, Ataman, Yuan, Shaopeng, Polak, Lisa, Kulukian, Anita, Chai, Sophia, Fuchs, Elaine

“…In Fig. 2g of this Article, a panel was inadvertently duplicated. The ‘D30 IMQ’ image was a duplicate of the ‘D6 Ctrl’ image. Fig. 2g has been corrected online…”
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