Search Results - "Yuan, Renyikun"
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Natural products to prevent drug resistance in cancer chemotherapy: a review
Published in Annals of the New York Academy of Sciences (01-08-2017)“…Chemotherapy is the standard internal medical treatment for cancer. However, the resistance of cancer cells to nearly all kinds of chemotherapeutic drugs and…”
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Fe-Curcumin Nanozyme-Mediated Reactive Oxygen Species Scavenging and Anti-Inflammation for Acute Lung Injury
Published in ACS central science (26-01-2022)“…Pneumonia, such as acute lung injury (ALI), has been a type of lethal disease that is generally caused by uncontrolled inflammatory response and excessive…”
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Procyanidin A2, a polyphenolic compound, exerts anti-inflammatory and anti-oxidative activity in lipopolysaccharide-stimulated RAW264.7 cells
Published in PloS one (05-08-2020)“…Procyandin A2 (PCA2) is a polyphenolic compound which is isolated from grape seeds. It has been reported that PCA2 exhibits antioxidative and anti-inflammatory…”
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Abrine, an IDO1 inhibitor, suppresses the immune escape and enhances the immunotherapy of anti-PD-1 antibody in hepatocellular carcinoma
Published in Frontiers in immunology (24-05-2023)“…Indoleamine-2,3-dioxygenase 1 (IDO1) is responsible for tumor immune escape by regulating T cell-associated immune responses and promoting the activation of…”
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Cucurbitacin B inhibits TGF-β1-induced epithelial-mesenchymal transition (EMT) in NSCLC through regulating ROS and PI3K/Akt/mTOR pathways
Published in Chinese medicine (19-02-2022)“…Lung cancer is the leading cause of cancer mortality worldwide, and most of the patients after treatment with EGF-TKIs develop drug resistance, which is…”
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Hederasaponin C Alleviates Lipopolysaccharide-Induced Acute Lung Injury In Vivo and In Vitro Through the PIP2/NF-κB/NLRP3 Signaling Pathway
Published in Frontiers in immunology (25-02-2022)“…Gene transcription is governed by epigenetic regulation that is essential for the pro-inflammatory mediators surge following pathological triggers. Acute lung…”
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Discovery of New Heterocyclic/Benzofuran Hybrids as Potential Anti-Inflammatory Agents: Design, Synthesis, and Evaluation of the Inhibitory Activity of Their Related Inflammatory Factors Based on NF-κB and MAPK Signaling Pathways
Published in International journal of molecular sciences (01-02-2023)“…NF-κB and MAPK are classic inflammation signaling pathways which regulate inflammation signal transmission and induce the expression of many inflammatory…”
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Dihydrotanshinone Triggers Porimin-Dependent Oncosis by ROS-Mediated Mitochondrial Dysfunction in Non-Small-Cell Lung Cancer
Published in International journal of molecular sciences (26-07-2023)“…Lung cancer is one of the leading causes of cancer death. Non-small-cell lung cancer (NSCLC) accounts for the majority of lung cancer diagnoses…”
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Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway
Published in Chinese medicine (28-06-2021)“…Abstract Background Tanshinone I (TI) is a primary component of Salvia miltiorrhiza Bunge (Danshen), which confers a favorable role in a variety of…”
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Ginsenoside Rb1 exerts therapeutic effects on ulcerative colitis through regulating the Nrf2/PIP2/NLRP3 inflammasome signaling pathway
Published in Journal of functional foods (01-03-2023)“…[Display omitted] •GRb1 has a therapeutic effect on UC.•GRb1 plays a therapeutic role in UC by targeting Nrf2 and regulating the Nrf2/PIP2/NLRP3 pathway.•GRb1…”
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Prenylated chromones and flavonoids isolated from the roots of Flemingia macrophylla and their anti-lung cancer activity
Published in Chinese medicine (23-11-2023)“…Abstract Background The successful launch of icaritin, a therapeutic drug for liver cancer derived from Epimedium brevicornu , has provided new impetus for the…”
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Anemoside B4 Protects against Acute Lung Injury by Attenuating Inflammation through Blocking NLRP3 Inflammasome Activation and TLR4 Dimerization
Published in Journal of immunology research (2020)“…Acute lung injury (ALI) is an acute inflammatory process in the lung parenchyma. Anemoside B4 (B4) was isolated from Pulsatilla, a plant-based drug against…”
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Oleuropein Attenuates Lipopolysaccharide-Induced Acute Kidney Injury In Vitro and In Vivo by Regulating Toll-Like Receptor 4 Dimerization
Published in Frontiers in pharmacology (24-03-2021)“…Acute kidney injury (AKI) is a common critical illness that involves multiple systems and multiple organs with a rapid decline in kidney function over short…”
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Anemoside B4 protects against Klebsiella pneumoniae - and influenza virus FM1-induced pneumonia via the TLR4/Myd88 signaling pathway in mice
Published in Chinese medicine (02-07-2020)“…Pneumonia refers to the inflammation of the terminal airway, alveoli and pulmonary interstitium, which can be caused by pathogenic microorganisms, physical and…”
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Novel compounds in fruits of coriander (Coşkuner & Karababa) with anti-inflammatory activity
Published in Journal of functional foods (01-10-2020)“…[Display omitted] •Four new compounds were identified in Coriander (Coriandrum Sativum L.).•Compound 3 exhibited a significant anti-inflammatory…”
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Sugarcane leaf polysaccharide exerts a therapeutic effect on cardiovascular diseases through necroptosis
Published in Heliyon (01-11-2023)“…Necroptosis, a novel form of programmed cell death wherein the necrotic morphology is characterized by swelling of the cells, rupture of the plasma membrane,…”
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Nuezhenide Exerts Anti-Inflammatory Activity through the NF-κB Pathway
Published in Current molecular pharmacology (01-01-2021)“…Nuezhenide (NZD), an iridoid glycoside isolated from Ilex pubescens Hook. & Arn. var. kwangsiensis Hand.-Mazz., used as a traditional Chinese medicine for…”
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2-Methoxy-6-Acetyl-7-Methyljuglone (MAM) Induces iNOS/NO-mediated DNA Damage Response through Activation of MAPKs Pathways
Published in Anti-cancer agents in medicinal chemistry (01-01-2018)“…Background:There are inconsistent reports about the role of Nitric Oxide (NO) in cancer progression and prevention. Quinones demonstrate significant…”
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Rapid Identification of the Chemical Components of Ilex rotunda Thunb Using UPLC-Q-TOF-MS/MS
Published in Journal of chemistry (30-09-2021)“…Ilicis Rotundae Cortex (IRC) consists of the bark of Ilex rotunda Thunb, and its chemical constituents mainly include flavonoid glycosides, phenols, and…”
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