Search Results - "Yuan, Qiuyue"

Integration of single-cell multi-omics data by regression analysis on unpaired observations by Yuan, Qiuyue, Duren, Zhana

“…Despite recent developments, it is hard to profile all multi-omics single-cell data modalities on the same cell. Thus, huge amounts of single-cell genomics…”
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Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity by Shi, Xiaohan, Li, Yunguang, Yuan, Qiuyue, Tang, Shijie, Guo, Shiwei, Zhang, Yehan, He, Juan, Zhang, Xiaoyu, Han, Ming, Liu, Zhuang, Zhu, Yiqin, Gao, Suizhi, Wang, Huan, Xu, Xiongfei, Zheng, Kailian, Jing, Wei, Chen, Luonan, Wang, Yong, Jin, Gang, Gao, Dong

“…Chromatin accessibility plays an essential role in controlling cellular identity and the therapeutic response of human cancers. However, the chromatin…”
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Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation by Xin, Jingxue, Zhang, Hui, He, Yaoxi, Duren, Zhana, Bai, Caijuan, Chen, Lang, Luo, Xin, Yan, Dong-Sheng, Zhang, Chaoyu, Zhu, Xiang, Yuan, Qiuyue, Feng, Zhanying, Cui, Chaoying, Qi, Xuebin, Ouzhuluobu, Wong, Wing Hung, Wang, Yong, Su, Bing

“…High-altitude adaptation of Tibetans represents a remarkable case of natural selection during recent human evolution. Previous genome-wide scans found many…”
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Heritability enrichment in context-specific regulatory networks improves phenotype-relevant tissue identification by Feng, Zhanying, Duren, Zhana, Xin, Jingxue, Yuan, Qiuyue, He, Yaoxi, Su, Bing, Wong, Wing Hung, Wang, Yong

“…Systems genetics holds the promise to decipher complex traits by interpreting their associated SNPs through gene regulatory networks derived from comprehensive…”
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Aberrant Expression of Long Non-coding RNAs in Exosomes in Follicle Fluid From PCOS Patients by Wang, Liping, Fan, Hairui, Zou, Yinggang, Yuan, Qiuyue, Hu, Xuming, Chen, Xujing, Zhu, Chunhui, Zhang, Xiaomei, Cui, Hengmi

“…Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disease characterized by persistent anovulation and hyperandrogenism, affecting…”
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ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming by Li, Fei, Yuan, Qiuyue, Di, Wei, Xia, Xinyi, Liu, Zhuang, Mao, Ninghui, Li, Lin, Li, Chunfeng, He, Juan, Li, Yunguang, Guo, Wangxin, Zhang, Xiaoyu, Zhu, Yiqin, Aji, Rebiguli, Wang, Shangqian, Tong, Xinyuan, Ji, Hongbin, Chi, Ping, Carver, Brett, Wang, Yong, Chen, Yu, Gao, Dong

“…Although cancer is commonly perceived as a disease of dedifferentiation, the hallmark of early-stage prostate cancer is paradoxically the loss of more plastic…”
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Structure-property relationship of polyetheramines as clay-swelling inhibitors in water-based drilling fluids by Peng, Bo, Luo, Ping-Ya, Guo, Wen-Yu, Yuan, Qiuyue

“…The influences of structure parameters of polyetheramines as clay‐swelling inhibitors in water‐based drilling fluids on the application performances were…”
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3Scover: Identifying Safeguard TF from Cell Type-TF Specificity Network by an Extended Minimum Set Cover Model by Yuan, Qiuyue, Wang, Yong

“…Transcription factors (TFs) define cellular identity either by activating target cell program or by silencing donor program as demonstrated by intensive cell…”
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Multiple-Tissue and Multilevel Analysis on Differentially Expressed Genes and Differentially Correlated Gene Pairs for HFpEF by Zhou, Guofeng, Sun, Shaoyan, Yuan, Qiuyue, Zhang, Run, Jiang, Ping, Li, Guangyu, Wang, Yong, Li, Xiao

“…Heart failure with preserved ejection fraction (HFpEF) is a complex disease characterized by dysfunctions in the heart, adipose tissue, and cerebral arteries…”
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Inferring gene regulatory networks from single-cell multiome data using atlas-scale external data by Yuan, Qiuyue, Duren, Zhana

“…Existing methods for gene regulatory network (GRN) inference rely on gene expression data alone or on lower resolution bulk data. Despite the recent…”
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MIMIC: an optimization method to identify cell type-specific marker panel for cell sorting by Zou, Meng, Duren, Zhana, Yuan, Qiuyue, Li, Henry, Hutchins, Andrew Paul, Wong, Wing Hung, Wang, Yong

“…Multi-omics data allow us to select a small set of informative markers for the discrimination of specific cell types and study of cellular heterogeneity…”
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MicroRNA-124-3p affects proliferation, migration and apoptosis of bladder cancer cells through targeting AURKA by Yuan, Qiuyue, Sun, Tingge, Ye, Feng, Kong, Weisheng, Jin, Haofan

“…The aim of this study was to establish the relationship between miR-124-3p and Aurora A kinase (AURKA) in bladder cancer (BC). The expressions of miR-124-3p…”
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Identification of a three-gene signature in the triple-negative breast cancer by WANG, LIPING, LUO, ZHOU, SUN, MINMIN, YUAN, QIUYUE, ZOU, YINGGANG, FU, DEYUAN

“…This work aimed to improve current prognostic signatures based on clinical stages in identifying high-risk patients of triple-negative breast cancer (TNBC), to…”
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ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming by Li, Fei, Yuan, Qiuyue, Di, Wei, Xia, Xinyi, Liu, Zhuang, Mao, Ninghui, Li, Lin, Li, Chunfeng, He, Juan, Li, Yunguang, Guo, Wangxin, Zhang, Xiaoyu, Zhu, Yiqin, Aji, Rebiguli, Wang, Shangqian, Tong, Xinyuan, Ji, Hongbin, Chi, Ping, Carver, Brett, Wang, Yong, Chen, Yu, Gao, Dong

“…Although cancer is commonly perceived as a disease of dedifferentiation, the hallmark of early-stage prostate cancer is paradoxically the loss of more plastic…”
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Integrated characterization of hepatobiliary tumor organoids provides a potential landscape of pharmacogenomic interactions by Zhu, Yanjing, Tang, Shijie, Yuan, Qiuyue, Fu, Jing, He, Juan, Liu, Zhuang, Zhao, Xiaofang, Li, Yunguang, Zhao, Yan, Zhang, Yani, Zhang, Xiaoyu, Zhang, Yangqianwen, Zhu, Yiqin, Wang, Wenwen, Zheng, Bo, Wu, Rui, Wu, Tong, Yang, Shuai, Qiu, Xinyao, Shen, Siyun, Hu, Ji, Chen, Luonan, Wang, Yong, Wang, Hongyang, Gao, Dong, Chen, Lei

“…Despite considerable efforts to identify human liver cancer genomic alterations that might unveil druggable targets, the systematic translation of multiomics…”
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