Search Results - "Yuan, Menglang"

A therapeutically targetable positive feedback loop between lnc-HLX-2-7, HLX, and MYC that promotes group 3 medulloblastoma by Katsushima, Keisuke, Joshi, Kandarp, Yuan, Menglang, Romero, Brigette, Batish, Mona, Stapleton, Stacie, Jallo, George, Kolanthai, Elayaraja, Seal, Sudipta, Saulnier, Olivier, Taylor, Michael D., Wechsler-Reya, Robert J., Eberhart, Charles G., Perera, Ranjan J.

“…Recent studies suggest that long non-coding RNAs (lncRNAs) contribute to medulloblastoma (MB) formation and progression. We have identified an lncRNA,…”
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Medulloblastoma cerebrospinal fluid reveals metabolites and lipids indicative of hypoxia and cancer-specific RNAs by Lee, Bongyong, Mahmud, Iqbal, Pokhrel, Rudramani, Murad, Rabi, Yuan, Menglang, Stapleton, Stacie, Bettegowda, Chetan, Jallo, George, Eberhart, Charles G, Garrett, Timothy, Perera, Ranjan J

“…Medulloblastoma (MB) is the most common malignant brain tumor in children. There remains an unmet need for diagnostics to sensitively detect the disease,…”
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DC - SIGNR by influencing the lncRNA HNRNPKP2 upregulates the expression of CXCR4 in gastric cancer liver metastasis by Zhang, Yu, Zhang, Qianshi, Zhang, Mengyang, Yuan, Menglang, Wang, Zhaohui, Zhang, Jingbo, Zhou, Xu, Zhang, Yinan, Lin, Fang, Na, Heya, Ren, Shuangyi, Zuo, Yunfei

“…Profiling evidences of selectin demonstrate that they play an crucial role in cancer progression and metastasis. However, DC-SIGNR as a family member of…”
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Novel roles of DC-SIGNR in colon cancer cell adhesion, migration, invasion, and liver metastasis by Na, Heya, Liu, Xiaoli, Li, Xiaomeng, Zhang, Xinsheng, Wang, Yu, Wang, Zhaohui, Yuan, Menglang, Zhang, Yu, Ren, Shuangyi, Zuo, Yunfei

“…Tumor metastasis is an essential cause of the poor prognosis of colon cancer. DC-SIGNR is a C-type lectin that is frequently found on human liver sinusoidal…”
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Novel roles of LSECtin in gastric cancer cell adhesion, migration, invasion, and lymphatic metastasis by Zhang, Yinan, Feng, Zhen, Xu, Yue, Jiang, Sufen, Zhang, Qianshi, Zhang, Zhenyu, Wang, Keyong, Li, Xiaomeng, Xu, Lijie, Yuan, Menglang, Chen, Zihao, Cui, Jingyi, Wu, Han, Gao, Yina, Wei, Wei, Wang, Bo, Zuo, Yunfei, Ren, Shuangyi

“…Liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin) plays an important regulatory role in a variety of diseases, including tumors…”
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Systematic transcriptomic analysis of childhood medulloblastoma identifies N6-methyladenosine-dependent lncRNA signatures associated with molecular subtype, immune cell infiltration, and prognosis by Joshi, Kandarp, Yuan, Menglang, Katsushima, Keisuke, Saulnier, Olivier, Ray, Animesh, Amankwah, Ernest, Stapleton, Stacie, Jallo, George, Taylor, Michael D, Eberhart, Charles G, Perera, Ranjan J

“…Medulloblastoma, the most common malignant pediatric brain tumor, is classified into four main molecular subgroups, but group 3 and group 4 tumors are…”
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TIGAR Promotes Tumorigenesis and Protects Tumor Cells From Oxidative and Metabolic Stresses in Gastric Cancer by Liu, Zhenhua, Wu, Yue, Zhang, Yingqiu, Yuan, Menglang, Li, Xuelu, Gao, Jiyue, Zhang, Shanni, Xing, Chengjuan, Qin, Huamin, Zhao, Hongbo, Zhao, Zuowei

“…Cancer cells adopt glycolysis to facilitate the generation of biosynthetic substrates demanded by cell proliferation and growth, and to adapt to stress…”
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CircNOLC1 Promotes Colorectal Cancer Liver Metastasis by Interacting with AZGP1 and Sponging miR‐212‐5p to Regulate Reprogramming of the Oxidative Pentose Phosphate Pathway by Yuan, Menglang, Zhang, Xinsheng, Yue, Fangxia, Zhang, Feifan, Jiang, Sufen, Zhou, Xu, Lv, Jinjuan, Zhang, Zhenyu, Sun, Yuzhu, Chen, Zihao, Wu, Han, Liu, Xiaoqian, Yu, Xiaoqi, Wei, Bowen, Jiang, Kexin, Lin, Fang, Zuo, Yunfei, Ren, Shuangyi

“…Liver metastasis is a common cause of death in progressive colorectal cancer patients, but the molecular mechanisms remain unclear. Here, it is reported that a…”
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The oncogenic circular RNA circ_63706 is a potential therapeutic target in sonic hedgehog-subtype childhood medulloblastomas by Katsushima, Keisuke, Pokhrel, Rudramani, Mahmud, Iqbal, Yuan, Menglang, Murad, Rabi, Baral, Prabin, Zhou, Rui, Chapagain, Prem, Garrett, Timothy, Stapleton, Stacie, Jallo, George, Bettegowda, Chetan, Raabe, Eric, Wechsler-Reya, Robert J, Eberhart, Charles G, Perera, Ranjan J

“…Medulloblastoma (MB) develops through various genetic, epigenetic, and non-coding (nc) RNA-related mechanisms, but the roles played by ncRNAs, particularly…”
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MicroRNA-4316 inhibits gastric cancer proliferation and migration via directly targeting VEGF-A by Mousa, Haithm, Yuan, Menglang, Zhang, Xinsheng, Li, Xiaomeng, Shopit, Abdullah, Almoiliqy, Marwan, Alshwmi, Mohammed, Al-Dherasi, Aisha, Xu, Yue, Zuo, Yunfei

“…microRNAs (miRNAs) have been reported to regulate proliferation and migration by down-regulating the expression of target genes. The aims of this study were to…”
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Application of double layered end-to-end anastomosis with continuous manual suture for completing digestive tract reconstruction in totally laparoscopic distal gastrectomy by Zhang, XinSheng, Zhang, WeiBin, Yuan, MengLang, Shi, XiaoMeng, Chen, HongYi, Feng, Zhen, Chen, ZiHao, Liu, DunBo, Yan, EnJun, Ren, ShuangYi

“…We retrospectively reviewed and consecutively collected the clinical data of distal gastric cancer patients who received surgical treatment, and we discuss the…”
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Correction to: Medulloblastoma cerebrospinal fluid reveals metabolites and lipids indicative of hypoxia and cancer-specific RNAs by Lee, Bongyong, Mahmud, Iqbal, Pokhrel, Rudramani, Murad, Rabi, Yuan, Menglang, Stapleton, Stacie, Bettegowda, Chetan, Jallo, George, Eberhart, Charles G, Garrett, Timothy, Perera, Ranjan J

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miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4 by Yuan, Menglang, Mahmud, Iqbal, Katsushima, Keisuke, Joshi, Kandarp, Saulnier, Olivier, Pokhrel, Rudramani, Lee, Bongyong, Liyanage, Wathsala, Kunhiraman, Haritha, Stapleton, Stacie, Gonzalez-Gomez, Ignacio, Kannan, Rangaramanujam M, Eisemann, Tanja, Kolanthai, Elayaraja, Seal, Sudipta, Garrett, Timothy J, Abbasi, Saed, Bockley, Kimberly, Hanes, Justin, Chapagain, Prem, Jallo, George, Wechsler-Reya, Robert J, Taylor, Michael D, Eberhart, Charles G, Ray, Animesh, Perera, Ranjan J

“…The prognosis of childhood medulloblastoma (MB) is often poor, and it usually requires aggressive therapy that adversely affects quality of life. microRNA-211…”
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DC-SIGN–LEF1/TCF1–miR-185 feedback loop promotes colorectal cancer invasion and metastasis by Yuan, Menglang, Zhang, Xinsheng, Zhang, Jingbo, Wang, Keyong, Zhang, Yu, Shang, Wei, Zhang, Yinan, Cui, Jingyi, Shi, Xiaomeng, Na, Heya, Fang, Deyu, Zuo, Yunfei, Ren, Shuangyi

“…DC-SIGN is previously focused on its physiologic and pathophysiologic roles in immune cells. Little is known about whether DC-SIGN is expressed in malignant…”
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DDDR-31. THE THERAPEUTIC POTENTIAL OF THE LONG NON-CODING RNA LNC-HLX-2-7 IN GROUP 3 MEDULLOBLASTOMAS IN CHILDREN by Katsushima, Keisuke, Yuan, Menglang, Lee, Bongyong, Stapleton, Stacie, Jallo, George, Seal, Sudipta, Eberhart, Charles, Perera, Ranjan

“…Abstract Medulloblastoma (MB) is an aggressive brain tumor that predominantly affects children. Recent high-throughput sequencing studies suggest that the…”
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MP44-18 E3 UBIQUITIN-PROTEIN LIGASE, TETRATRICOPEPTIDE REPEAT DOMAIN 3 (TTC3), H4 CLUSTERED HISTONE 5 (H4C5), AND EPITHELIAL CELL ADHESION MOLECULE (EPCAM) ARE NOVEL URINE-ENRICHED LIQUID BIOPSY BIOMARKERS TO DETECT PROSTATE CANCER IN MEN by Yuan, Menglang, Moschovas, Marcio, Perera, Roshane, Lee, Bongyong, Miller, Alexandra, Amankwah, Ernest, Pokhrel, Rudramani, Pavlovich, Christian, Sonpavde, Guru, Patel, Vipul, Perera, Ranjan

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MDB-70. SYSTEMATIC TRANSCRIPTOMIC ANALYSIS OF CHILDHOOD MEDULLOBLASTOMA IDENTIFIES M6A-LNCRNA SIGNATURES ASSOCIATED WITH PROGNOSIS, MOLECULAR SUBTYPE, AND IMMUNE CELL INFILTRATION by Joshi, Kandarp, Yuan, Menglang, Katsushima, Keisuke, Saulnier, Olivier, Dean, Selah, Amankwah, Ernest, Stapleton, Stacie, Jallo, George, Taylor, Michael D, Eberhart, Charles G, Perera, Ranjan J

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MDB-01. A POSITIVE FEEDBACK LOOP BETWEENLNC-HLX-2-7, HLX, AND MYC STRONGLY PROMOTES GROUP 3 MEDULLOBLASTOMA by Katsushima, Keisuke, Joshi, Kandarp, Yuan, Menglang, Batish, Mona, Stapleton, Stacie, Jallo, George, Seal, Sudipta, Taylor, Michael D, Wechsler-Reya, Rober J, Eberhart, Charles G, Perera, Ranjan J

“…Recent studies suggest that long non-coding RNAs (lncRNAs) contribute to medulloblastoma formation and progression. We have identified a lncRNA, lnc-HLX-2-7 ,…”
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EXTH-80. THE MOLECULAR FUNCTION AND THE THERAPEUTIC POTENTIAL OF MICRORNA-211 IN GROUP 3 MEDULLOBLASTOMAS IN CHILDREN by Yuan, Menglang, Katsushima, Keisuke, Pokhrel, Rudramani, Lee, Bongyong, Stapleton, Stacie, Jallo, George, Raabe, Eric, Eberhart, Charles, Perera, Ranjan

“…Abstract Medulloblastoma is a central nervous system tumor that primarily affects children and requires aggressive therapy. Patients often suffer from…”
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CSIG-32. microRNA 211, A POTENTIAL THERAPEUTIC AGENT FOR GROUP 3 MEDULLOBLASTOMA IN CHILDREN by Katsushima, Keisuke, Lee, Bongyong, Yuan, Menglang, Kunhiraman, Haritha, Stapleton, Stacie, Jallo, George, Raabe, Eric, Eberhart, Charles, Perera, Ranjan

“…Abstract Medulloblastoma (MB) is a central nervous system (CNS) tumor that predominantly affects children and requires aggressive therapy. Affected individuals…”
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