Search Results - "Yuan, Menglan"

Proteolytic Release and Nuclear Translocation of Notch-1 Are Induced by Presenilin-1 and Impaired by Pathogenic Presenilin-1 Mutations by Song, Weihong, Nadeau, Philip, Yuan, Menglan, Yang, Xudong, Shen, Jie, Yankner, Bruce A.

“…The Notch family of proteins consists of transmembrane receptors that play a critical role in the determination of cell fate. Genetic studies in Caenorhabditis…”
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Apoptosis Induced by Infection of Primary Brain Cultures with Diverse Human Immunodeficiency Virus Type 1 Isolates: Evidence for a Role of the Envelope by Ohagen, A, Ghosh, S, He, J, Huang, K, Chen, Y, Yuan, M, Osathanondh, R, Gartner, S, Shi, B, Shaw, G, Gabuzda, D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Regulation of CC Chemokine Receptor 5 and CD4 Expression and Human Immunodeficiency Virus Type 1 Replication in Human Macrophages and Microglia by T Helper Type 2 Cytokines by Wang, Jianbin, Crawford, Keith, Yuan, Menglan, Wang, Hui, Gorry, Paul R., Gabuzda, Dana

“…Macrophages, microglia, and other mononuclear phagocytes serve as cellular reservoirs for viral persistence in patients with acquired immunodeficiency…”
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Acceleration of Amyloid β-Peptide Aggregation by Physiological Concentrations of Calcium by Isaacs, Adrian M., Senn, David B., Yuan, Menglan, Shine, James P., Yankner, Bruce A.

“…Alzheimer disease is characterized by the accumulation of aggregated amyloid β-peptide (Aβ) in the brain. The physiological mechanisms and factors that…”
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Altered Metabolism of the Amyloid β Precursor Protein Is Associated with Mitochondrial Dysfunction in Down's Syndrome by Busciglio, Jorge, Pelsman, Alejandra, Wong, Caine, Pigino, Gustavo, Yuan, Menglan, Mori, Hiroshi, Yankner, Bruce A.

“…Most Down's syndrome (DS) patients develop Alzheimer's disease (AD) neuropathology. Astrocyte and neuronal cultures derived from fetal DS brain show…”
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Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1 by Zhang, Z, Nadeau, P, Song, W, Donoviel, D, Yuan, M, Bernstein, A, Yankner, B A

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Aging renders the brain vulnerable to amyloid β-protein neurotoxicity by Guela, Changiz, Wu, Chuang-Kuo, Saroff, Daniel, Lorenzo, Alfredo, Yuan, Menglan, Yankner, Bruce A

“…The formation of fibrillar deposits of amyloid beta protein (Abeta) in the brain is a pathological hallmark of Alzheimer's disease (AD). A central question is…”
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Amyloid β interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease by Yankner, Bruce A, Lorenzo, Alfredo, Yuan, Menglan, Zhang, Zhuohua, Paganetti, Paolo A, Sturchler-Pierrat, Christine, Staufenbiel, Matthias, Mautino, Jorge, Vigo, Francisco Sol, Sommer, Bernd

“…Amyloid beta protein (Abeta) deposition in the brain is a hallmark of Alzheimer's disease (AD). The fibrillar form of Abeta is neurotoxic, although the…”
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Acceleration of Amyloid β-Peptide Aggregation by Physiological Concentrations of Calcium by Adrian M. Isaacs, David B. Senn, Menglan Yuan, James P. Shine, Bruce A. Yankner

“…Alzheimer disease is characterized by the accumulation of aggregated amyloid β-peptide (Aβ) in the brain. The physiological mechanisms and factors that…”
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P4-351 Transthyretin expression in the aging brain and modulation of Aβ deposition by Isaacs, Adrian M., Yuan, Menglan, Yankner, Bruce A.

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Altered Metabolism of the Amyloid [beta] Precursor Protein Is Associated with Mitochondrial Dysfunction in Down's Syndrome by Busciglio, Jorge, Pelsman, Alejandra, Wong, Caine, Pigino, Gustavo, Yuan, Menglan, Mori, Hiroshi, Yankner, Bruce A

“…Most Down's syndrome (DS) patients develop Alzheimer's disease (AD) neuropathology. Astrocyte and neuronal cultures derived from fetal DS brain show…”
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Presenilins are required for -secretase cleavage of -APP and transmembrane cleavage of Notch-1 by Yankner, Bruce A, Zhang, Zhuohua, Nadeau, Philip, Song, Weihong, Donoviel, Dorit, Yuan, Menglan, Bernstein, Alan

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Regulation of endogenous amyloid β-protein production by APOE in a human cortical culture model by Nadeau, Philip M., Yuan, Menglan, Geula, Changiz, Weisgraber, Karl, Younkin, Steven G., Yankner, Bruce A.

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Regulation of notch-1 cleavage and signaling by presenilin-1 by Song, Weihong, Nadeau, Philip M., Yuan, Menglan, Yang, Xudong, Shen, Jie, Yankner, Bruce A.

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Amyloid b interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease by Lorenzo, Alfredo, Yuan, Menglan, Zhang, Zhuohua, Paganetti, Paolo A, Sturchler-Pierrat, Christine, Staufenbiel, Matthias, Mautino, Jorge, Vigo, Francisco Sol, Sommer, Bernd, Yankner, Bruce A

“…Amyloid b protein (Ab) deposition in the brain is a hallmark of Alzheimer's disease (AD). The fibrillar form of Ab is neurotoxic, although the mechanism of its…”
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Amyloid [beta] interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease by Lorenzo, Alfredo, Yuan, Menglan, Zhang, Zhuohua, Paganetti, Paolo A, Sturchler-Pierrat, Christine, Staufenbiel, Matthias, Mautino, Jorge, Francisco Sol Vigo, Sommer, Bernd, Yankner, Bruce A

“…Amyloid beta protein (Abeta) deposition in the brain is a hallmark of Alzheimer's disease (AD). The fibrillar form of Abeta is neurotoxic, although the…”
Get full text