Search Results - "Yuan, Liyun"

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos by Zuo, Erwei, Sun, Yidi, Wei, Wu, Yuan, Tanglong, Ying, Wenqin, Sun, Hao, Yuan, Liyun, Steinmetz, Lars M, Li, Yixue, Yang, Hui

“…Genome editing holds promise for correcting pathogenic mutations. However, it is difficult to determine off-target effects of editing due to single-nucleotide…”
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Glutathione in liver diseases and hepatotoxicity by Yuan, Liyun, Kaplowitz, Neil

“…Glutathione (GSH) is a major antioxidant as well as redox and cell signaling regulator. GSH guards cells against oxidative injury by reducing H 2O 2 and…”
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Bile acid receptors and nonalcoholic fatty liver disease by Yuan, Liyun, Bambha, Kiran

“…With the high prevalence of obesity, diabetes, and otherfeatures of the metabolic syndrome in United States,nonalcoholic fatty liver disease （NAFLD） has…”
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Mechanisms of Drug-induced Liver Injury by Yuan, Liyun, MD, PhD, Kaplowitz, Neil, MD

“…Drug-induced liver injury (DILI) represents a broad spectrum of liver manifestations. However, the most common manifestation is hepatocyte death following drug…”
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S3085 Recurrent Gastrointestinal Bleeding From an Isolated Ectopic Ileal Varix by Tien, Christine, Rajaratnam, Matthew, Tonthat, Alexander, Salamo, Russell, Yuan, Liyun

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S1910 Differential Effect of Cardiometabolic Risk Factors on Mortality in US Adults With Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) by Dukewich, Matthew, Dodge, Jennifer L., Yuan, Liyun, Terrault, Norah A.

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Portrait of Regional Trends in Liver Transplantation for Nonalcoholic Steatohepatitis in the United States by Yuan, Liyun, Hanlon, Courtney L., Terrault, Norah, Alqahtani, Saleh, Tamim, Hani, Lai, Michelle, Saberi, Behnam

“…Nonalcoholic steatohepatitis (NASH) is one of the most common etiologies of liver transplantation (LT) in the United States. We investigated regional trends in…”
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S1268 Association of Obesity and Metabolic Determinants with Colonic Neoplasia in Latinx Populations: A Highlight of Sex-Based Differences by Tamai, Robert, Dawit, Lillian, Lee, Patrick, Simmons, Okeefe, Ding, Li, Yuan, Liyun

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GOTI, a method to identify genome-wide off-target effects of genome editing in mouse embryos by Zuo, Erwei, Sun, Yidi, Wei, Wu, Yuan, Tanglong, Ying, Wenqin, Sun, Hao, Yuan, Liyun, Steinmetz, Lars M., Li, Yixue, Yang, Hui

“…Genome editing holds great potential for correcting pathogenic mutations. We developed a method called GOTI (genome-wide off-target analysis by two-cell embryo…”
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Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria by Han, Derick, Dara, Lily, Win, Sanda, Than, Tin Aung, Yuan, Liyun, Abbasi, Sadeea Q, Liu, Zhang-Xu, Kaplowitz, Neil

“…Drugs that cause liver injury often ‘stress’ mitochondria and activate signal transduction pathways important in determining cell survival or death. In most…”
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S2098 AI Assisted Colonoscopy Improves Polyp Detection in Obese Patients by Wang, Sarah J., Wang, Daniel, Chang, Patrick, Bakr, Omar, Sharma, Nisha, Nguyen, Denis, Kong, Niwen, Amini, Maziar, Ong, Justin, Bruce, Dara, Lee, Helen, Phan, Jennifer, Yuan, Liyun, Sahakian, Ara, Buxbaum, James

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Comparison of the accuracy of 9 intraocular lens power calculation formulas after SMILE in Chinese myopic eyes by Li, Liangpin, Yuan, Liyun, Yang, Kun, Wu, Yanan, Alafati, Simayilijiang, Hua, Xia, Wang, Yan, Yuan, Xiaoyong

“…As of 2021, over 2.8 million small-incision lenticule extraction (SMILE) procedures have been performed in China. However, knowledge regarding the selection of…”
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PGG.Han: the Han Chinese genome database and analysis platform by Gao, Yang, Zhang, Chao, Yuan, Liyun, Ling, YunChao, Wang, Xiaoji, Liu, Chang, Pan, Yuwen, Zhang, Xiaoxi, Ma, Xixian, Wang, Yuchen, Lu, Yan, Yuan, Kai, Ye, Wei, Qian, Jiaqiang, Chang, Huidan, Cao, Ruifang, Yang, Xiao, Ma, Ling, Ju, Yuanhu, Dai, Long, Tang, Yuanyuan, Zhang, Guoqing, Xu, Shuhua

“…Abstract As the largest ethnic group in the world, the Han Chinese population is nonetheless underrepresented in global efforts to catalogue the genomic…”
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Setd2 supports GATA3+ST2+ thymic-derived Treg cells and suppresses intestinal inflammation by Ding, Zhaoyun, Cai, Ting, Tang, Jupei, Sun, Hanxiao, Qi, Xinyi, Zhang, Yunpeng, Ji, Yan, Yuan, Liyun, Chang, Huidan, Ma, Yanhui, Zhou, Hong, Li, Li, Sheng, Huiming, Qiu, Ju

“…Treg cells acquire distinct transcriptional properties to suppress specific inflammatory responses. Transcription characteristics of Treg cells are regulated…”
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A Review of Research on Recyclable Polymer Materials by Yuan, Liyun, Shen, Yong

“…Polymer materials have been widely used in applications ranging from aerospace, automobile transportation, medical and health care due to their excellent…”
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Alterations in anterior lens capsule structure and LTBP-2 expression in primary angle-closure glaucoma by Tian, Xiaofeng, Yuan, Liyun, Li, Liangpin, Yuan, Xiaoyong

“…ObjectiveThis study investigated the role of latent-transforming growth factor β-binding protein 2 (LTBP-2) in primary angle-closure glaucoma (PACG) by…”
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Integrated co-expression network analysis uncovers novel tissue-specific genes in major depressive disorder and bipolar disorder by Han, Mengyao, Yuan, Liyun, Huang, Yuwei, Wang, Guiying, Du, Changsheng, Wang, Qingzhong, Zhang, Guoqing

“…Tissue-specific gene expression has been found to be associated with multiple complex diseases including cancer, metabolic disease, aging, etc. However, few…”
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Comparative analysis of IOL power calculations in postoperative refractive surgery patients: a theoretical surgical model for FS-LASIK and SMILE procedures by Li, Liangpin, Yuan, Liyun, Yang, Kun, Wu, Yanan, Hua, Xia, Wang, Yan, Yuan, Xiaoyong

“…Abstract Background As the two most prevalent refractive surgeries in China, there is a substantial number of patients who have undergone Femtosecond…”
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Whole-genome sequencing of 128 camels across Asia reveals origin and migration of domestic Bactrian camels by Ming, Liang, Yuan, Liyun, Yi, Li, Ding, Guohui, Hasi, Surong, Chen, Gangliang, Jambl, Tuyatsetseg, Hedayat-Evright, Nemat, Batmunkh, Mijiddorj, Badmaevna, Garyaeva Khongr, Gan-Erdene, Tudeviin, Ts, Batsukh, Zhang, Wenbin, Zulipikaer, Azhati, Hosblig, Erdemt, Natyrov, Arkady, Mamay, Prmanshayev, Narenbatu, Meng, Gendalai, Narangerel, Choijilsuren, Khongorzul, Orgodol, He, Jing, Hai, Le, Lin, Weili, Sirendalai, Sarentuya, Aiyisi, Li, Yixue, Wang, Zhen, Jirimutu

“…The domestic Bactrian camels were treated as one of the principal means of locomotion between the eastern and western cultures in history. However, whether…”
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Effects of district parameters, green space and building density on thermal comfort- a case study of Badaguan District in Qingdao by Zhu, Ruirui, Liu, Yibin, Yan, Baowen, Zhang, Xiaotong, Yuan, Liyun, Wang, Yefan, Pan, Yanting

“…It is challenging for most Historical Preservation Areas (HPA) to improve thermal comfort, especially under the contradiction of urban preservation. The study…”
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