Search Results - "Yuan, Jingsong"

A new modified Weibull distribution by Almalki, Saad J., Yuan, Jingsong

“…We introduce a new lifetime distribution by considering a serial system with one component following a Weibull distribution and another following a modified…”
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FIGNL1-containing protein complex is required for efficient homologous recombination repair by Yuan, Jingsong, Chen, Junjie

“…The RAD51 recombinase plays a central role in homologous recombination (HR), which is critical for repair of DNA double-strand breaks, maintenance of genomic…”
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The annealing helicase HARP protects stalled replication forks by Yuan, Jingsong, Ghosal, Gargi, Chen, Junjie

“…Mutations in HepA-related protein (HARP) are the only identified causes of Schimke immunoosseous dysplasia (SIOD). HARP has a unique annealing helicase…”
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The HARP-like Domain-Containing Protein AH2/ZRANB3 Binds to PCNA and Participates in Cellular Response to Replication Stress by Yuan, Jingsong, Ghosal, Gargi, Chen, Junjie

“…Proteins with annealing activity are newly identified ATP-dependent motors that can rewind RPA-coated complementary single-stranded DNA bubbles. AH2 (annealing…”
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Geared Toward Applications: A Perspective on Functional Sequence-Controlled Polymers by Yang, Cangjie, Wu, Kevin B, Deng, Yu, Yuan, Jingsong, Niu, Jia

“…Sequence-controlled polymers are an emerging class of synthetic polymers with a regulated sequence of monomers. In the past decade, tremendous progress has…”
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FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair by Liu, Ting, Ghosal, Gargi, Yuan, Jingsong, Chen, Junjie, Huang, Jun

“…Fanconi anemia (FA) is caused by mutations in 13 Fanc genes and renders cells hypersensitive to DNA interstrand cross-linking (ICL) agents. A central event in…”
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MRE11-RAD50-NBS1 Complex Dictates DNA Repair Independent of H2AX by Yuan, Jingsong, Chen, Junjie

“…DNA double-strand breaks (DSBs) represent one of the most serious forms of DNA damage that can occur in the genome. Here, we show that the DSB-induced…”
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ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1 by Zhang, Peijing, Wei, Yongkun, Wang, Li, Debeb, Bisrat G., Yuan, Yuan, Zhang, Jinsong, Yuan, Jingsong, Wang, Min, Chen, Dahu, Sun, Yutong, Woodward, Wendy A., Liu, Yongqing, Dean, Douglas C., Liang, Han, Hu, Ye, Ang, K. Kian, Hung, Mien-Chie, Chen, Junjie, Ma, Li

“…Epithelial–mesenchymal transition (EMT) is associated with characteristics of breast cancer stem cells, including chemoresistance and radioresistance. However,…”
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REV7 counteracts DNA double-strand break resection and affects PARP inhibition by Xu, Guotai, Chapman, J. Ross, Brandsma, Inger, Yuan, Jingsong, Mistrik, Martin, Bouwman, Peter, Bartkova, Jirina, Gogola, Ewa, Warmerdam, Daniël, Barazas, Marco, Jaspers, Janneke E., Watanabe, Kenji, Pieterse, Mark, Kersbergen, Ariena, Sol, Wendy, Celie, Patrick H. N., Schouten, Philip C., van den Broek, Bram, Salman, Ahmed, Nieuwland, Marja, de Rink, Iris, de Ronde, Jorma, Jalink, Kees, Boulton, Simon J., Chen, Junjie, van Gent, Dik C., Bartek, Jiri, Jonkers, Jos, Borst, Piet, Rottenberg, Sven

“…Loss of REV7 is shown to regulate end resection of double-stranded DNA breaks in BRCA1-deficient cells, leading to PARP inhibitor resistance and restoration of…”
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PTPN14 is required for the density-dependent control of YAP1 by Wang, Wenqi, Huang, Jun, Wang, Xin, Yuan, Jingsong, Li, Xu, Feng, Lin, Park, Jae-Il, Chen, Junjie

“…Through an shRNA-mediated loss-of-function screen, we identified PTPN14 as a potential tumor suppressor. PTPN14 interacts with yes-associated protein 1 (YAP1),…”
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N Terminus of CtIP Is Critical for Homologous Recombination-mediated Double-strand Break Repair by Yuan, Jingsong, Chen, Junjie

“…DNA double-strand breaks (DSBs) represent one of the most lethal types of DNA damage cells encounter. CtIP (also known as RBBP8) acts together with the MRN…”
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The Role of the Human SWI5-MEI5 Complex in Homologous Recombination Repair by Yuan, Jingsong, Chen, Junjie

“…The Swi5-Mei5 complex and its homologues are involved in specialized recombination pathways in budding and fission yeasts. Although the fission yeast homologue…”
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Relatlimab: a novel drug targeting immune checkpoint LAG-3 in melanoma therapy by Su, Jingjing, Fu, Yiting, Cui, Zitong, Abidin, Zain, Yuan, Jingsong, Zhang, Xinmiao, Li, Runmin, Zhao, Chunzhen

“…Relatlimab is a type of human immunoglobulin G4 monoclonal blocking antibody. It is the world's first Lymphocyte-Activation Gene-3 (LAG-3) inhibitor and the…”
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Mitosis-specific MRN complex promotes a mitotic signaling cascade to regulate spindle dynamics and chromosome segregation by Xu, Ran, Xu, Yixi, Huo, Wei, Lv, Zhicong, Yuan, Jingsong, Ning, Shaokai, Wang, Qingsong, Hou, Mei, Gao, Ge, 高歌, Ji, Jianguo, Chen, Junjie, Guo, Rong, Xu, Dongyi

“…The MRE11–RAD50–NBS1 (MRN) complex is well known for participating in DNA damage response pathways in all phases of cell cycle. Here, we show that MRN…”
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Antibiotic use in pig farming and its associated factors in L County in Yunnan, China by Fang, Jing, Gong, Guodong, Yuan, Jingsong, Sun, Xiao

“…China has a long history of pig rearing, and it currently raises and consumes approximately half of the pigs in the world. Major improvements have been made in…”
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Therapeutic Protein PEPylation: The Helix of Nonfouling Synthetic Polypeptides Minimizes Antidrug Antibody Generation by Hou, Yingqin, Zhou, Yu, Wang, Hao, Sun, Jialing, Wang, Ruijue, Sheng, Kai, Yuan, Jingsong, Hu, Yali, Chao, Yu, Liu, Zhuang, Lu, Hua

“…Polymer conjugation is a clinically proven approach to generate long acting protein drugs with decreased immune responses. Although poly­(ethylene glycol)…”
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Clustered, Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9-coupled Affinity Purification/Mass Spectrometry Analysis Revealed a Novel Role of Neurofibromin in mTOR Signaling by Li, Xu, Gao, Min, Choi, Jong Min, Kim, Beom-Jun, Zhou, Mao-Tian, Chen, Zhen, Jain, Antrix N., Jung, Sung Yun, Yuan, Jingsong, Wang, Wenqi, Wang, Yi, Chen, Junjie

“…Neurofibromin (NF1) is a well known tumor suppressor that is commonly mutated in cancer patients. It physically interacts with RAS and negatively regulates RAS…”
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Tooth loss and osteoporosis: the osteodent study by Nicopoulou-Karayianni, Kety, Tzoutzoukos, Panagiotis, Mitsea, Anastasia, Karayiannis, Athanasios, Tsiklakis, Kostas, Jacobs, Reinhilde, Lindh, Christina, Van Der Stelt, Paul, Allen, Philip, Graham, Jim, Horner, Keith, Devlin, Hugh, Pavitt, Susan, Yuan, Jingsong

“…Aim: To determine the cross‐sectional association of the osteoporotic status of patients with the number of their teeth, with and without taking into account…”
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A climatologic investigation of the SARS-CoV outbreak in Beijing, China by Yuan, Jingsong, Yun, Hongmin, Lan, Wei, Wang, Wei, Sullivan, Sheena G., Jia, Shaowei, Bittles, Alan H.

“…The first cases of severe acute respiratory syndrome (SARS) were identified in November 2002, in Guangdong Province, China. The epidemic spread rapidly within…”
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Overexpression of Osteopontin Is Associated with More Aggressive Phenotypes in Human Non–Small Cell Lung Cancer by Hu, Zhi, Lin, Dongmei, Yuan, Jingsong, Xiao, Ting, Zhang, Husheng, Sun, Wenyue, Han, Naijun, Ma, Ying, Di, Xuebing, Gao, Meixia, Ma, Jinfang, Zhang, Junhang, Cheng, Shujun, Gao, Yanning

“…Purpose: The extracellular matrix (ECM) molecule osteopontin is implicated in many pathologic processes, including inflammation, cell proliferation, ECM…”
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